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anti-Mouse (Murine) beta Endorphin Anticorps:
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Carp Polyclonal beta Endorphin Primary Antibody pour IEM, ICC - ABIN617878
Pinessi, Rainero, de Gennaro, Violante, Cassano, Matera, Cesano: Cerebrospinal fluid and plasma concentrations of POMC-related peptides in multiple sclerosis. dans Annals of the New York Academy of Sciences 1992
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Human Monoclonal beta Endorphin Primary Antibody pour IHC (f), IHC (p) - ABIN93907
Andjelkov, Elvenes, Figenschau, Bjorkoy, Knutsen, Seternes, Johansen: Detection of mRNA transcripts of truncated opiate precursor (POMC) in human cartilage. dans Cell biochemistry and function 2006
Human Monoclonal beta Endorphin Primary Antibody pour IHC (fro), IF - ABIN111318
Ubuka, Lai, Kitani, Suzuuchi, Pham, Cadigan, Wang, Chowdhury, Tsutsui, Bentley: Gonadotropin-inhibitory hormone identification, cDNA cloning, and distribution in rhesus macaque brain. dans The Journal of comparative neurology 2009
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Data indicate the regulation of energy balance in BMPR1A (Montrer BMPR1A Anticorps)-mediated appetite regulation in POMC (Montrer POMC Anticorps) neurons.
POMC (Montrer POMC Anticorps) and AgRP (Montrer AGRP Anticorps) neurons receive direct steroid- and frequency-dependent glutamatergic synaptic input from Kiss1 (Montrer KISS1 Anticorps)(ARC (Montrer NOL3 Anticorps)) neurons in male mice
Localization of the dopamine receptors of types 1 and 2 on the bodies of POMC (Montrer POMC Anticorps)-expressing neurons of the arcuate nucleus of the hypothalamus in mice and rats.(
disruption of this hippocampal POMC (Montrer POMC Anticorps)/MC4R (Montrer MC4R Anticorps) circuit might contribute to synaptic dysfunction observed in Alzheimer's disease.
The data show that somatic MORs in POMC (Montrer POMC Anticorps) neurons couple to multiple effectors that have differential sensitivity to desensitization of the receptor.
These findings indicate that the relevance of AgRP (Montrer AGRP Anticorps) to POMC (Montrer POMC Anticorps) neuron GABA connectivity depends on the state of AgRP (Montrer AGRP Anticorps) neuron activity and suggest that different types of transmitter release should be considered when circuit mapping.
these data unmasked a role for mitochondrial fission in leptin (Montrer LEP Anticorps) sensitivity and glucose sensing of POMC (Montrer POMC Anticorps) neurons.
it is suggested that the suppression of NeuroD1 (Montrer NEUROD1 Anticorps) expression and the inhibition of NeuroD1 (Montrer NEUROD1 Anticorps)/E-box interaction may play an important role in the Gc-mediated negative regulation of Pomc (Montrer POMC Anticorps).
To clarify the functional roles of the AKT (Montrer AKT1 Anticorps)-mTOR (Montrer FRAP1 Anticorps) pathway in the hippocampal neurons, we generated conditional knockout mice harboring the deletion of Pten (Pten (Montrer PTEN Anticorps)-cKO) in Proopiomelanocortin (Montrer POMC Anticorps)-expressing neurons.
Epo (Montrer EPO Anticorps) regulates hypothalamus POMC (Montrer POMC Anticorps) expression via STAT3 (Montrer STAT3 Anticorps) activation.
E2F1 (Montrer E2F1 Anticorps)-mediated hPOMC transcription is a potential target for suppressing ACTH (Montrer POMC Anticorps) production in ectopic Cushing's syndrome.
Elevated ACTH (Montrer POMC Anticorps) secretion is associated with Cushing's syndrome.
a novel p53 (Montrer TP53 Anticorps)/POMC (Montrer POMC Anticorps)/Galphas (Montrer GNAS Anticorps)/SASH1 (Montrer SASH1 Anticorps) autoregulatory positive feedback loop is regulated by SASH1 (Montrer SASH1 Anticorps) mutations to induce pathological hyperpigmentation phenotype.
Data suggest that alpha-MSH enhances cell adhesion to fibronectin (Montrer FN1 Anticorps) in primary mixed synoviocytes obtained from osteoarthritis patients; alpha-MSH reduces secretion of cytokines (TNF (Montrer TNF Anticorps), IL-6 (Montrer IL6 Anticorps) and IL-8 (Montrer IL8 Anticorps)) in such synoviocyte cultures.
Data suggest that the first screening step diagnosis for pituitary adenoma was determined based upon immunohistochemical (IHC) scores for Pit-1 (Montrer POU1F1 Anticorps), SF-1 (Montrer NR5A1 Anticorps), and ACTH (Montrer POMC Anticorps).
The aim of this survey is to evaluate the association of genetic variants of melanocortin-4-receptor (MC4R (Montrer MC4R Anticorps)), pro-opiomelanocortin (POMC (Montrer POMC Anticorps)), apolipoprotein E (APOE (Montrer APOE Anticorps)) and agouti-related protein (AGRP (Montrer AGRP Anticorps)) with obesity in the North Indian population.
The expression of Pomc (Montrer POMC Anticorps) mRNA was stimulated in the arcuate nucleus after skin exposure to UVB.
hsa (Montrer CD24 Anticorps)-miR (Montrer MLXIP Anticorps)-34a can regulate the CRH (Montrer CRH Anticorps)/CRHR1 (Montrer CRHR1 Anticorps)/POMC (Montrer POMC Anticorps) axis and may influence body mass index.
these common variants in PCSK1 (Montrer PCSK1 Anticorps) and POMC (Montrer POMC Anticorps) were not the major cause of obesity in the Thai subjects sampled. However, variants in PCSK1 (Montrer PCSK1 Anticorps) did affect cholesterol level, LDL-C level, and waist circumference.
ACTH (Montrer POMC Anticorps) was readily detected at significantly higher levels in regions of ACTH (Montrer POMC Anticorps)-secreting adenomas and in normal anterior adenohypophysis compared with non-secreting adenoma and neurohypophysis.
The association has been reported between polymorphisms of the CRH (Montrer CRH Anticorps) and POMC (Montrer POMC Anticorps) genes with economic traits in Korean cattle.
Expression of the hepatic endocannabinoid system and proopiomelanocortin (Montrer POMC Anticorps) was altered by plane of dietary energy prepartum particularly during the first 2-week postpartum.
Significant associations were observed between POMC (Montrer POMC Anticorps) c.288C>T with start-of-finishing weight (SOF (Montrer GJA1 Anticorps) WT; P = 0.04), hot carcass weight (HCW; P = 0.02), average fat and grade fat (both P = 0.05), carcass rib-eye area (REA (Montrer PHB2 Anticorps); P = 0.03) and marbling
The polymorphism of POMC (Montrer POMC Anticorps) gene is associated with the growth traits of Nanyang cattle.
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used\; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.
adrenal corticotropic hormone
, adrenocorticotropic hormone
, alpha-melanocyte stimulating hormone
, corticotropin-like intermediary peptide
, melanotropin gamma
, alpha-melanocyte-stimulating hormone
, beta-melanocyte-stimulating hormone
, lipotropin beta
, lipotropin gamma
, melanotropin alpha
, melanotropin beta
, opiomelanocortin prepropeptide
, proopiomelanocortin preproprotein
, beta-melanocyte stimulating hormone
, proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin)