Aperçu des produits pour anti-Dual Specificity Phosphatase 3 (DUSP3) Anticorps

Full name:
anti-Dual Specificity Phosphatase 3 Anticorps (DUSP3)
Chez www.anticorps-enligne.fr sont 81 Dual Specificity Phosphatase 3 (DUSP3) Anticorps de 17 de différents fournisseurs disponibles. De plus, nous expédions Dual Specificity Phosphatase 3 Protéines (15) et Dual Specificity Phosphatase 3 Kits (4) et beaucoup plus de produits pour cette protéine. Un total de 105 Dual Specificity Phosphatase 3 produits sont actuellement listés.
Synonymes:
2210015O03Rik, 5031436O03Rik, dusp3, RGD1560049, si:bz18k17.3, si:rp71-18k17.3, T-DSP11, VHR
afficher tous les anticorps Gène GeneID UniProt
DUSP3 1845 P51452
DUSP3 498003  
DUSP3 72349 Q9D7X3

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anti-Dual Specificity Phosphatase 3 Anticorps mieux référencés

  1. Human Polyclonal DUSP3 Primary Antibody pour EIA, IHC (p) - ABIN360840 : Alonso, Rahmouni, Williams, van Stipdonk, Jaroszewski, Godzik, Abraham, Schoenberger, Mustelin: Tyrosine phosphorylation of VHR phosphatase by ZAP-70. dans Nature immunology 2002 (PubMed)
    Show all 5 references for 360840

  2. Chicken Monoclonal DUSP3 Primary Antibody pour IF, IP - ABIN968030 : Alonso, Saxena, Williams, Mustelin: Inhibitory role for dual specificity phosphatase VHR in T cell antigen receptor and CD28-induced Erk and Jnk activation. dans The Journal of biological chemistry 2001 (PubMed)
    Show all 4 references for 968030

  3. Human Polyclonal DUSP3 Primary Antibody pour IHC (p), WB - ABIN392924 : Wang, Yeh, Chou, Yang, Fu, Chen, Cheng, Huang, Liu, Huang, Chen: Vaccinia H1-related phosphatase is a phosphatase of ErbB receptors and is down-regulated in non-small cell lung cancer. dans The Journal of biological chemistry 2011 (PubMed)

Plus d’anticorps contre Dual Specificity Phosphatase 3 partenaires d’interaction

Human Dual Specificity Phosphatase 3 (DUSP3) interaction partners

  1. In PTP1B (Montrer PTPN1 Anticorps) and VHR, two new allosteric clusters were identified in each enzyme.

  2. In the phosphatase-silenced cells, the normal bipolar spindle structure was restored by chemical inhibition of Erk1/2 (Montrer MAPK1/3 Anticorps) and ectopic overexpression of Dusp3. We propose that at M phase Dusp3 keeps Erk1/2 (Montrer MAPK1/3 Anticorps) activity in check to facilitate normal mitosis.

  3. Data suggest levels of gene expression of both DUSP3 (dual specificity phosphatase 3) and PSME3 (proteasome activator subunit 3 (Montrer PSME3 Anticorps)) are associated with susceptibility to Staphylococcus aureus infection/sepsis in humans and in mouse disease model.

  4. Our results demonstrate that DUSP3 plays a key and nonredundant role as a regulator of innate immune responses

  5. VHR can dimerize inside cells, and that VHR catalytic activity is reduced upon dimerization.

  6. DUSP3 is a pro-angiogenic atypical dual-specificity phosphatase.

  7. DUSP3 interacting partners are nucleolar proteins involved in processes related to DNA repair and senescence.

  8. we report the first successful site-specific incorporation of sulfotyrisine into VHR through the use of expanding genetic code

  9. Proteins containing the class II motifs are efficient VHR substrates in vitro, suggesting that VHR may act on a novel class of yet unidentified Tyr (Montrer TYR Anticorps)(P) proteins in vivo.

  10. VHR expression enhances the signaling of ErbB (Montrer EGFR Anticorps) receptors and may be involved in NSCLC pathogenesis.

Mouse (Murine) Dual Specificity Phosphatase 3 (DUSP3) interaction partners

  1. Data suggest levels of gene expression of both Dusp3 (dual specificity phosphatase 3) and Psme3 (proteasome activator subunit 3 (Montrer PSME3 Anticorps)) are associated with susceptibility to Staphylococcus aureus infection/sepsis in humans and in mouse disease model.

  2. Platelets from DUSP3-deficient mice displayed a selective impairment of aggregation and granule secretion.

  3. Our results demonstrate that DUSP3 plays a key and nonredundant role as a regulator of innate immune responses

  4. DUSP3 is a pro-angiogenic atypical dual-specificity phosphatase.

Dual Specificity Phosphatase 3 (DUSP3) profil antigène

Antigen Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.

Alternative names and synonyms associated with Dual Specificity Phosphatase 3 (DUSP3)

  • dual specificity phosphatase 3 (DUSP3) anticorps
  • dual specificity phosphatase 3b (dusp3b) anticorps
  • dual specificity phosphatase 3 (Dusp3) anticorps
  • dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) (Dusp3) anticorps
  • 2210015O03Rik anticorps
  • 5031436O03Rik anticorps
  • dusp3 anticorps
  • RGD1560049 anticorps
  • si:bz18k17.3 anticorps
  • si:rp71-18k17.3 anticorps
  • T-DSP11 anticorps
  • VHR anticorps

Protein level used designations for DUSP3

dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) , dual specificity phosphatase 3 , dual specificity protein phosphatase 3 , dual specificity protein phosphatase VHR , serine/threonine specific protein phosphatase , vaccinia H1-related phosphatase , vaccinia virus phosphatase VH1-related

GENE ID SPECIES
425527 Gallus gallus
468271 Pan troglodytes
568344 Danio rerio
713686 Macaca mulatta
1845 Homo sapiens
498003 Rattus norvegicus
480505 Canis lupus familiaris
615432 Bos taurus
72349 Mus musculus
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