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anti-Human SH3G2 Anticorps:
anti-Mouse (Murine) SH3G2 Anticorps:
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Rat (Rattus) Polyclonal SH3G2 Primary Antibody pour ICC, IHC - ABIN1742336
Wahl, Katiyar, Schmitz: A local, periactive zone endocytic machinery at photoreceptor synapses in close vicinity to synaptic ribbons. dans The Journal of neuroscience : the official journal of the Society for Neuroscience 2013
Show all 2 Pubmed References
Human Polyclonal SH3G2 Primary Antibody pour ELISA, IHC - ABIN4308123
Shang, Guo, Fu, Fu, Sun: SH3GL2 gene participates in MEK-ERK signal pathway partly by regulating EGFR in the laryngeal carcinoma cell line Hep2. dans Medical science monitor : international medical journal of experimental and clinical research 2010
Human Polyclonal SH3G2 Primary Antibody pour ICC, IF - ABIN4308121
Kannan, Wells, Sivakumar, Komatsu, Singh, Samten, Philley, Sauter, Ikebe, Idell, Gupta, Dasgupta: Mitochondrial Reprogramming Regulates Breast Cancer Progression. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2016
Human Monoclonal SH3G2 Primary Antibody pour IHC (p), ELISA - ABIN562863
Dasgupta, Jang, Shao, Mukhopadhyay, Sokhi, Das, Brait, Talbot, Yung, Begum, Westra, Hoque, Yang, Yi, Lam, Gazdar, Fisher, Jen, Sidransky: SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling. dans Journal of molecular medicine (Berlin, Germany) 2013
Endophilin-1 was a direct and functional downstream target of miR (Montrer MLXIP Anticorps)-107.
Methylation status of SH3GL2 gene was associated with the TNM (Montrer ODZ1 Anticorps) staging and HPV infection status of vulvar squamous cell carcinoma.
Endophilin-1 positively regulated blood-brain barrier permeability via the EGFR (Montrer EGFR Anticorps)-JNK (Montrer MAPK8 Anticorps) signaling pathway in hCMEC/D3 cells, which would provide an experimental basis for further research on endophilin-1 mediated the opening of blood-brain barrier .
these results reveal a novel function of postsynaptic endophilin A1 in spine morphogenesis, stabilization and synaptic function through the regulation of p140Cap (Montrer SRCIN1 Anticorps)
Data indicate that the presence of the susceptible G allele in SNP rs1049430 is associated with the inactivation of SH3-domain GRB2-like 2 protein (SH3GL2) and could be used as a prognostic marker of head and neck squamous cell carcinoma (HNSCC).
study described that endophilin-1 is expressed in hCMEC/D3 cells where it regulates the permeability of blood-brain barrier by altering the expression of ZO-1 (Montrer TJP1 Anticorps) and occludin (Montrer OCLN Anticorps) via the EGFR (Montrer EGFR Anticorps)-ERK1/2 (Montrer MAPK1/3 Anticorps) pathway
miR (Montrer MLXIP Anticorps)-330 negatively regulated the expression of SH3GL2 in GSCs, which promoted the oncogenic progression of GSCs through activating ERK (Montrer EPHB2 Anticorps) and PI3K (Montrer PIK3CA Anticorps)/AKT (Montrer AKT1 Anticorps) signaling pathways.
these findings identify loss of Sh3gl2 as a frequent event in Urothelial carcinoma (UC) development that promotes disease progression.
this study suggests a novel mechanism in which Lpd mediates EGFR endocytosis via Mena downstream of endophilin.
Overexpression of EGFR in head and neck squamous cell carcinoma is associated with inactivation of SH3GL2 and CDC25A genes.
Transcriptional analysis of endophilin-A mutant mice, complemented by proteomics, highlighted ataxia- and protein-homeostasis-related genes and revealed upregulation of the E3-ubiquitin ligase (Montrer MUL1 Anticorps) FBXO32/atrogin-1 (Montrer FBXO32 Anticorps) and its transcription factor FOXO3A (Montrer FOXO3 Anticorps).
retrolinkin is a binding partner of endophilin A1 and that both proteins are required for BDNF (Montrer BDNF Anticorps)-induced dendrite outgrowth
Data report that the parkin ubiquitin-like domain binds SH3 domains from endocytic BAR proteins such as endophilin-A with an affinity comparable to proline-rich domains from well-established SH3 partners.
Tip-to-tip interactions between the BAR domains in a trigonal crystal form of Snx9 (Montrer SNX9 Anticorps)(PX-BAR) reminiscent of functionally important interactions described for F-BAR domains.
Results sugest that reduced or defective OPHN1 (Montrer OPHN1 Anticorps) signaling impairs synaptic vesicle cycling at hippocampal synapses.
interacts with synaptojanin and dynamin I\; may be involved in synaptic vesicle recycling
Endophilin A1 BAR domain
, SH3 domain protein 2A
, SH3 domain-containing GRB2-like protein 2
, bA335L15.1 (SH3-domain GRB2-like 2)
, endophilin A1
, endophilin I
, SH3 domain-containing GRB2-like protein 1