Aperçu des produits pour anti-High Mobility Group AT-Hook 1 (HMGA1) Anticorps

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anti-High Mobility Group AT-Hook 1 Anticorps (HMGA1)
Chez www.anticorps-enligne.fr sont 133 High Mobility Group AT-Hook 1 (HMGA1) Anticorps de 22 de différents fournisseurs disponibles. De plus, nous expédions High Mobility Group AT-Hook 1 Protéines (20) et High Mobility Group AT-Hook 1 Kits (14) et beaucoup plus de produits pour cette protéine. Un total de 179 High Mobility Group AT-Hook 1 produits sont actuellement listés.
Synonymes:
AL023995, ENSMUSG00000041059, HMG-I(Y), HMG-R, HMG-Y, HMGA1, Hmga1a, Hmga1b, Hmgi, Hmgi-rs1, Hmgiy, Hmgy, wu:fb12b06, wu:fb18f11, wu:fc19f01, wu:fi38b05, zgc:85677

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anti-High Mobility Group AT-Hook 1 Anticorps mieux référencés

  1. Human Polyclonal HMGA1 Primary Antibody pour FACS, IF - ABIN653050 : Mu, Liu, Zhou, Xu, Jiang, Wang, Qu: Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation, invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. dans Human pathology 2010 (PubMed)
    Show all 2 references for 653050

  2. Human Polyclonal HMGA1 Primary Antibody pour IHC, ELISA - ABIN185443 : Chiappetta, Botti, Monaco, Pasquinelli, Pentimalli, Di Bonito, DAiuto, Fedele, Iuliano, Palmieri, Pierantoni, Giancotti, Fusco: HMGA1 protein overexpression in human breast carcinomas: correlation with ErbB2 expression. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2004 (PubMed)
    Show all 2 references for 185443

  3. Human Polyclonal HMGA1 Primary Antibody pour ELISA, WB - ABIN451785 : Liau, Rocha, Matros, Redston, Whang: High mobility group AT-hook 1 (HMGA1) is an independent prognostic factor and novel therapeutic target in pancreatic adenocarcinoma. dans Cancer 2008 (PubMed)

Plus d’anticorps contre High Mobility Group AT-Hook 1 partenaires d’interaction

Mouse (Murine) High Mobility Group AT-Hook 1 (HMGA1) interaction partners

  1. Studies define a novel HMGA1-MMP-2 (Montrer MMP2 Anticorps) pathway involved in a subset of human carcinosarcomas and tumor progression in murine models.

  2. Mouse embryonic fibroblasts null for the Hmga1 gene show downregulation of Bub1 (Montrer BUB1 Anticorps), Bub1b (Montrer BUB1B Anticorps), Mad2l1 (Montrer MAD2L1 Anticorps) and Ttk SAC (Montrer ADCY10 Anticorps) genes, and present several features of chromosomal instability, such as nuclear abnormalities, binucleation, micronuclei and karyotypic alterations.

  3. Taken together, our data demonstrate that miR (Montrer MLXIP Anticorps)-625 suppresses cell proliferation and migration by targeting HMGA1 and suggest miR (Montrer MLXIP Anticorps)-625 as a promising prognostic biomarker and a potential therapeutic target for breast cancer.

  4. Inactivation of the Cdkn2a (Montrer CDKN2A Anticorps) locus cooperates with HMGA1 to drive T-cell leukemogenesis.

  5. Increased HMGA1 expression is associated with pituitary and thyroid tumors.

  6. activated HMGA1 regulates cell proliferation through the Notch1 (Montrer NOTCH1 Anticorps) signaling pathway, which represents an important molecular pathway leading to leukemogenesis.

  7. Data propose that, by affecting the expression of both IGFBP protein species, HMGA1 can serve as a modulator of IGF-I (Montrer IGF1 Anticorps) activity, thus representing an important novel mediator of glucose disposal.

  8. HMGA1 contributes to the neurogenic potential of neural precursor cells in the early stages of neocortical development.

  9. Elevated expression of HMGA1 is associated with the transition of prostate cancer (PCa (Montrer ENPP1 Anticorps)) cells from androgen-sensitive to androgen-independent growth and plays a role in the cell growth of androgen-independent PCa (Montrer ENPP1 Anticorps) cells.

  10. The data in the present study reveal a role of Hmga1 in transcriptional silencing in T cell lineages and leukemic cells.

Human High Mobility Group AT-Hook 1 (HMGA1) interaction partners

  1. We show that the chromatin remodeling protein HMGA1 functions as a downstream effector of these biological responses to miR (Montrer MLXIP Anticorps)-296-5p and regulates Sox2 (Montrer SOX2 Anticorps) expression, a master driver of cell stemness, by modifying chromatin architecture at the Sox2 (Montrer SOX2 Anticorps) promoter

  2. tissue microarray revealed that HMGA1 was expressed in thyroid carcinoma more than that in normal thyroid tissues ; expression of HMGA1 and MMP-2 (Montrer MMP2 Anticorps) was identified to be positively correlated . The present study established the first link between HMGA1 and TGF-b1 in the regulation of thyroid cancer proliferation and invasion

  3. our research indicated an H19 (Montrer NCKAP1 Anticorps)-miR138-HMGA1 pathway in regulating the migration and invasion of colon cancer, providing new insight for treatment of colon cancer.

  4. The results reported here indicate a critical role of HMGA1 in the development of glioblastoma multiforme; its suppression impairs proliferation and self-renewal of brain tumor stem cells

  5. miR (Montrer MLXIP Anticorps)-214 expression was poor while that of HMGA1 was high in cervical and colorectal cancer tissues. miR (Montrer MLXIP Anticorps)-214-re-expression or HMGA1 downregulation inhibited proliferation, migration and invasion of cancer cells while miR (Montrer MLXIP Anticorps)-214 inhibition had opposite effects. miR (Montrer MLXIP Anticorps)-214 was demonstrated to bind to the wild-type 3' untranslated region of HMGA1 but not with its mutant.

  6. HMGA1 is frequently expressed in cirrhotic tissues and HCCs (Montrer HCCS Anticorps) and its expression is associated with high Edmondson grade and worse prognosis in HCC (Montrer FAM126A Anticorps).

  7. Studies define a novel HMGA1-MMP-2 (Montrer MMP2 Anticorps) pathway involved in a subset of human carcinosarcomas and tumor progression in murine models.

  8. HMGA1 may function as an oncogene (Montrer RAB1A Anticorps) and modulate endometrial cancer cell migration and invasion by activating Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) pathway.

  9. Increased HMGA1 in pulmonary arterial endothelial cells resulting from dysfunctional BMPr2 (Montrer BMPR2 Anticorps) signaling can transition endothelium to smooth muscle-like cells associated with pulmonary arterial hypertension.

  10. in splenic hemangioma with t(3;6)(q26;p21 (Montrer CDKN1A Anticorps)), the entire coding region of HMGA1 comes under the control of the TBL1XR1 (Montrer TBL1XR1 Anticorps) promoter, bringing about dysregulation of HMGA1

Pig (Porcine) High Mobility Group AT-Hook 1 (HMGA1) interaction partners

  1. distinct loci exist for growth and fatness in the two populations and identified HMGA1 and PLAG1 (Montrer PLAG1 Anticorps) as strong candidate genes on SSC7 and SSC4, respectively.

  2. Characterization of polymorphisms in the HMGA1 gene in relation to growth and fat deposition.

Cow (Bovine) High Mobility Group AT-Hook 1 (HMGA1) interaction partners

  1. HMGA1 likely regulates certain aspects of the BoHV-1 latency-reactivation cycle.

High Mobility Group AT-Hook 1 (HMGA1) profil antigène

Antigen Summary

This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with High Mobility Group AT-Hook 1 (HMGA1)

  • high mobility group AT-hook I, related sequence 1 (Hmga1-rs1) anticorps
  • high mobility group protein HMG-I/HMG-Y (TSC_c24220) anticorps
  • high mobility group AT-hook 1a (hmga1a) anticorps
  • high mobility group AT-hook 1 (HMGA1) anticorps
  • high mobility group AT-hook 1 (Hmga1) anticorps
  • high mobility group AT-hook 1 (Hmg-i) anticorps
  • AL023995 anticorps
  • ENSMUSG00000041059 anticorps
  • HMG-I(Y) anticorps
  • HMG-R anticorps
  • HMG-Y anticorps
  • HMGA1 anticorps
  • Hmga1a anticorps
  • Hmga1b anticorps
  • Hmgi anticorps
  • Hmgi-rs1 anticorps
  • Hmgiy anticorps
  • Hmgy anticorps
  • wu:fb12b06 anticorps
  • wu:fb18f11 anticorps
  • wu:fc19f01 anticorps
  • wu:fi38b05 anticorps
  • zgc:85677 anticorps

Protein level used designations for HMGA1

high mobility group protein HMG-I/HMG-Y , HMG-I(Y) , high mobility group protein A1 , high mobility group AT-hook protein 1 , high mobility group AT-hook 1 , high-mobility group (nonhistone chromosomal) protein isoforms I and Y , high mobility group protein R , nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y , high mobility group HMGA1A , high mobility group HMGA1B , non-histone protein , high-mobility group AT-hook 1 , high mobility group protein I , High mobility group AT-hook protein 1 , High mobility group protein A1 , high mobility group-I protein

GENE ID SPECIES
111241 Mus musculus
10178543 Thermus scotoductus SA-01
406447 Danio rerio
705105 Macaca mulatta
746594 Pan troglodytes
3159 Homo sapiens
442946 Canis lupus familiaris
100157848 Sus scrofa
618849 Bos taurus
15361 Mus musculus
117062 Rattus norvegicus
378795 Gallus gallus
100689040 Cricetulus griseus
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