Aperçu des produits pour Mediator Complex Subunit 25 Protéines (MED25)

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Mediator Complex Subunit 25 Protéines (MED25)
Chez www.anticorps-enligne.fr sont 3 Mediator Complex Subunit 25 (MED25) Protéines de 2 de différents fournisseurs disponibles. De plus, nous expédions Mediator Complex Subunit 25 Anticorps (25) et Mediator Complex Subunit 25 Kits (11) et beaucoup plus de produits pour cette protéine. Un total de 42 Mediator Complex Subunit 25 produits sont actuellement listés.
Synonymes:
2610034E13Rik, 2610529E18Rik, ACID1, ARC92, CG12254, CMT2B2, dARC92, dDrip97, Dmel\\CG12254, ESTM2, LD07688, med25, P78, PTOV2, RGD1305137, X83308, zgc:63555
afficher tous les protéines Gène GeneID UniProt
MED25 81857 Q71SY5
Rat MED25 MED25 292889  
MED25 75613 Q8VCB2

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Mediator Complex Subunit 25 Protéines (MED25) par origine

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Plus protéines pour Mediator Complex Subunit 25 partenaires d'interaction

Human Mediator Complex Subunit 25 (MED25) interaction partners

  1. FOS strongly binds to the same MED25 (Montrer MED9 Protéines) site as ETV4 (Montrer ETV4 Protéines) activation domain and JUN (Montrer JUN Protéines) interacts with the other two MED25 (Montrer MED9 Protéines) sites.

  2. Med25 (Montrer MED9 Protéines), a variable member of the Mediator complex, is a coactivator of ligand-activated ERalpha (Montrer ESR1 Protéines) that interacts with ERalpha (Montrer ESR1 Protéines) through its C-terminal LXXLL motif after BPA (Montrer DST Protéines) exposure, and is functionally involved in BPA (Montrer DST Protéines)-induced transcriptional regulation of CYP2C9 (Montrer CYP2C9 Protéines) expression and enzyme activity.

  3. the critical region of chromosome 19 a homozygous variant (c.418C>T, p.Arg140Trp) in Mediator complex subunit 25 predicted as deleterious.

  4. A model is proposed in which the N-terminal transactivation domain of ERM (Montrer ETV5 Protéines) binds the MED25 (Montrer MED9 Protéines) VP16 H1 binding pocket in a helical conformation.

  5. Homozygous MED25 (Montrer MED9 Protéines) mutation implicated in eye-intellectual disability syndrome.

  6. MED25 (Montrer MED9 Protéines) is important for regulating the epigenetic landscape resulting in transcriptional activation of a highly inducible gene, CYP2C9 (Montrer CYP2C9 Protéines)

  7. Med25 (Montrer MED9 Protéines) is identified as a new coactivator of ERalpha (Montrer ESR1 Protéines) that is required for ERalpha (Montrer ESR1 Protéines)-mediated regulation of CYP2C9 (Montrer CYP2C9 Protéines) expression

  8. Mediator subunit MED25 (Montrer MED9 Protéines) plays a critical role in this process and identify a MED25 (Montrer MED9 Protéines) domain that serves as a docking site on Mediator for the ATF6alpha (Montrer ATF6 Protéines) transcription activation domain.

  9. the identification of MED25 (Montrer MED9 Protéines) as one of the HNF4alpha (Montrer HNF4A Protéines) binding partners in pancreatic ss-cells leading to insulin (Montrer INS Protéines) secretion which is impaired in MODY (Montrer HNF4A Protéines) patients

  10. solution NMR structure of protein MED25 (Montrer MED9 Protéines)(391-543), comprising the activator interacting domain of subunit 25 of mediator, is presented with the measurement of polypeptide backbone heteronuclear 15N-{1H} NOEs to identify fast internal motional modes

Mouse (Murine) Mediator Complex Subunit 25 (MED25) interaction partners

  1. the identification of MED25 as one of the HNF4alpha (Montrer HNF4A Protéines) binding partners in pancreatic ss-cells leading to insulin (Montrer INS Protéines) secretion which is impaired in MODY (Montrer HNF4A Protéines) patients

  2. Data show that Med25 is coordinately expressed with Pmp22 (Montrer PMP22 Protéines) gene dosage and expression in transgenic mice and rats, and suggest a potential role of this protein in the molecular etiology of Charcot-Marie-Tooth disease.

Profil protéine Mediator Complex Subunit 25 (MED25)

Profil protéine

This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2.

Alternative names and synonyms associated with Mediator Complex Subunit 25 (MED25)

  • Mediator complex subunit 25 (MED25)
  • mediator complex subunit 25 (MED25)
  • mediator complex subunit 25 (med25)
  • mediator complex subunit 25 (LOC100343629)
  • mediator complex subunit 25 (Med25)
  • mediator of RNA polymerase II transcription, subunit 25 homolog (yeast) (Med25)
  • mediator of RNA polymerase II transcription, subunit 25 homolog (yeast) (med25)
  • 2610034E13Rik Protéine
  • 2610529E18Rik Protéine
  • ACID1 Protéine
  • ARC92 Protéine
  • CG12254 Protéine
  • CMT2B2 Protéine
  • dARC92 Protéine
  • dDrip97 Protéine
  • Dmel\\CG12254 Protéine
  • ESTM2 Protéine
  • LD07688 Protéine
  • med25 Protéine
  • P78 Protéine
  • PTOV2 Protéine
  • RGD1305137 Protéine
  • X83308 Protéine
  • zgc:63555 Protéine

Protein level used designations for MED25

mediator complex subunit 25 , CG12254-PA , MED25-PA , mediator of RNA polymerase II transcription, subunit 25 homolog , mediator of RNA polymerase II transcription subunit 25 , mediator of RNA polymerase II transcription subunit 25-like , ARC/mediator transcriptional coactivator subunit , activator interaction domain-containing protein 1 , activator-recruited cofactor 92 kDa component , prostate-derived protein 78 kDa , mMED25 , mediator of RNA polymerase II transcription, subunit 9 homolog

GENE ID SPECIES
42385 Drosophila melanogaster
484374 Canis lupus familiaris
719061 Macaca mulatta
100124831 Xenopus (Silurana) tropicalis
100343629 Oryctolagus cuniculus
100385076 Callithrix jacchus
100444927 Pongo abelii
81857 Homo sapiens
292889 Rattus norvegicus
533865 Bos taurus
444205 Xenopus laevis
75613 Mus musculus
406793 Danio rerio
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