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Aperçu des produits pour anti-F2R (F2R) Anticorps

Full name:
anti-Coagulation Factor II (thrombin) Receptor Anticorps (F2R)
Chez sont 181 Coagulation Factor II (thrombin) Receptor (F2R) Anticorps de 26 de différents fournisseurs disponibles. De plus, nous expédions F2R Kits (62) et F2R Protéines (5) et beaucoup plus de produits pour cette protéine. Un total de 264 F2R produits sont actuellement listés.
AI482343, BXR, Cf2r, f2r-a, HTR, ONR1, PAR, Par-1, Par1, PAR2, PARq, PRR, PXR, SAR, SXR, ThrR, TR, TRGPC

Réactivités les plus populaires pour anti-F2R (F2R) Anticorps

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anti-Human F2R Anticorps:

anti-Mouse (Murine) F2R Anticorps:

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anti-F2R Anticorps mieux référencés

  1. Human Monoclonal F2R Primary Antibody pour IF, WB - ABIN968573 : Coughlin: How the protease thrombin talks to cells. dans Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 4 references for ABIN968573

  2. Human Polyclonal F2R Primary Antibody pour WB - ABIN611146 : Gradin, Larsson, Marklund, Gullberg: Regulation of microtubule dynamics by extracellular signals: cAMP-dependent protein kinase switches off the activity of oncoprotein 18 in intact cells. dans The Journal of cell biology 1998 (PubMed)
    Show all 3 references for ABIN611146

  3. Human Polyclonal F2R Primary Antibody pour IF (p), IHC (p) - ABIN728743 : Liu, Xie, Luo, Chen, Zhou, Xia, Chen, Zhou, Cao, Cao, Zhou: Identification of FLOT2 as a novel target for microRNA-34a in melanoma. dans Journal of cancer research and clinical oncology 2014 (PubMed)
    Show all 3 references for ABIN728743

  4. Human Polyclonal F2R Primary Antibody pour ELISA, WB - ABIN1536155 : Vu, Hung, Wheaton, Coughlin: Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. dans Cell 1991 (PubMed)

  5. Human Polyclonal F2R Primary Antibody pour ICC, IF - ABIN1742020 : Ossovskaya, Bunnett: Protease-activated receptors: contribution to physiology and disease. dans Physiological reviews 2004 (PubMed)

  6. Human Monoclonal F2R Primary Antibody pour FACS - ABIN4897018 : Hagag, Nosair, Ghaith, Elshenawy: Prognostic value of protease activated receptor-1 in children with acute lymphoblastic leukemia. dans Mediterranean journal of hematology and infectious diseases 2014 (PubMed)

  7. Human Polyclonal F2R Primary Antibody pour WB - ABIN452298 : Niessen, Schaffner, Furlan-Freguia, Pawlinski, Bhattacharjee, Chun, Derian, Andrade-Gordon, Rosen, Ruf: Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation. dans Nature 2008 (PubMed)

  8. Guinea Pig Polyclonal F2R Primary Antibody pour WB - ABIN2784606 : Kamio, Hashizume, Nakao, Matsushima, Sugiya: Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp. dans Biochemical pharmacology 2008 (PubMed)

Plus d’anticorps contre F2R partenaires d’interaction

Human Coagulation Factor II (thrombin) Receptor (F2R) interaction partners

  1. Extracellular granzyme K (Montrer GZMK Anticorps) mediates endothelial activation through the cleavage of PAR-1 (Montrer MARK2 Anticorps).

  2. Pregnane X receptor interacts with liver X receptor to regulate expression of SMPDL3A in primary hepatocytes.

  3. 66034T/C polymorphism of the human pregnane X receptor (Montrer NR1I2 Anticorps) (hPXR) is potential risk factor for drug-resistant epilepsy.

  4. The data suggest that some of the natural PXR (Montrer NR1I2 Anticorps) variants may have adverse physiological consequences owing to its influence on the expression levels and functional output of drug-metabolizing enzymes and transporters.

  5. miR (Montrer MLXIP Anticorps)-30c-1-3p was shown to alter the expression of CYP3A4 (Montrer CYP3A4 Anticorps), a prototypical target gene of PXR (Montrer NR1I2 Anticorps).

  6. The nuclear receptor PXR (Montrer NR1I2 Anticorps) regulates hepatic energy metabolism. (Review)

  7. Novel functions of PXR (Montrer NR1I2 Anticorps) in cardiometabolic disease development have been described. (Review)

  8. Acetylation of lysine 109 modulates PXR (Montrer NR1I2 Anticorps) DNA binding and transcriptional activity; PXR (Montrer NR1I2 Anticorps) acetylation status and transcriptional activity are modulated by E1A binding protein (p300 (Montrer EP300 Anticorps)) and SIRT1 (Montrer SIRT1 Anticorps).

  9. Genome-wide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR (Montrer NR1I2 Anticorps) and PPARalpha (Montrer PPARA Anticorps) in primary human hepatocytes has been presented.

  10. PXR (Montrer NR1I2 Anticorps) regulates the intestinal epithelial barrier during inflammation by modulating cytokine-induced MLCK (Montrer MYLK Anticorps) expression and JNK1 (Montrer MAPK8 Anticorps)/2 activation

Mouse (Murine) Coagulation Factor II (thrombin) Receptor (F2R) interaction partners

  1. thrombin (Montrer F2 Anticorps)/PAR-1 (Montrer MARK2 Anticorps) interaction regulated MCP-1 (Montrer CPT1B Anticorps), TF, MCSF (Montrer CSF1 Anticorps) and IL-6 (Montrer IL6 Anticorps) production.

  2. Thrombin (Montrer F2 Anticorps) upregulates LCN2 (Montrer LCN2 Anticorps) through protease-activated receptor-1 activation and causes brain damage.

  3. Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1 (Montrer MMP1 Anticorps)/protease-activated receptor-1 axis may play a role in neurogenesis following physiological and/or pathological stimuli.

  4. Data indicate an involvement of protease-activated receptor-1 in the neuroinflammation mediated by Eomes (Montrer EOMES Anticorps)(+) CD4 (Montrer CD4 Anticorps)(+) T cells.

  5. Bladder PAR (Montrer AFG3L2 Anticorps) activation elicits urothelial MIF (Montrer MIF Anticorps) release and urothelial MIF (Montrer MIF Anticorps) receptor signaling at least partly through CXCR4 (Montrer CXCR4 Anticorps) to result in abdominal hypersensitivity without overt bladder inflammation

  6. Data suggest that the pro-fibrotic effects of protease-activated receptor PAR-1 (Montrer MARK2 Anticorps) require the presence of protease-activated receptor PAR-2 (Montrer F2RL1 Anticorps).

  7. Thrombin (Montrer F2 Anticorps)-PAR1 signaling, via nitric oxide and EPCR (Montrer PROCR Anticorps), promotes hematopoietic stem cell (HSC (Montrer FUT1 Anticorps)) mobilization. aPC (Montrer APC Anticorps)-EPCR (Montrer PROCR Anticorps)-PAR1 signaling promotes HSC (Montrer FUT1 Anticorps) retention in bone marrow.

  8. Colonic adenocarcinoma growth was reduced in PAR-1 (Montrer MARK2 Anticorps)-deficient mice. Stromal cell-associated PAR-1 (Montrer MARK2 Anticorps) as one thrombin (Montrer F2 Anticorps) target important for tumor outgrowth.

  9. Interference with the thrombin (Montrer F2 Anticorps)-PAR1 system does not reduce the adverse effects of blood on germinal cells of the immature mouse brain.

  10. Protease activated receptor-1 deficiency diminishes bleomycin-induced skin fibrosis

Cow (Bovine) Coagulation Factor II (thrombin) Receptor (F2R) interaction partners

  1. MMP-1 (Montrer MMP1 Anticorps) promotes VEGFR2 (Montrer KDR Anticorps) expression and proliferation of endothelial cells through stimulation of PAR-1 and activation of NF-kappaB (Montrer NFKB1 Anticorps)

  2. PAR1 and PAR2 (Montrer F2RL1 Anticorps) regulate endothelial NO synthase (Montrer NOS Anticorps) phosphorylation and activity through G(12/13) and G(q), delineating the signaling pathways by which the proteases act on protease-activated receptors to modulate endothelial functions.

Pig (Porcine) Coagulation Factor II (thrombin) Receptor (F2R) interaction partners

  1. Thrombin (Montrer F2 Anticorps) stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA (Montrer RHOA Anticorps), and myocardin (Montrer MYOCD Anticorps).

  2. Thrombin (Montrer F2 Anticorps) induces a sustained contraction in the normal pulmonary artery, by activating PAR(1) and thereby increasing the sensitivity of the myofilament to Ca(2 (Montrer CA2 Anticorps)+).

F2R profil antigène

Antigen Summary

This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.

Alternative names and synonyms associated with F2R

  • coagulation factor 2 (thrombin) receptor (f2r) anticorps
  • coagulation factor II (thrombin) receptor (F2R) anticorps
  • coagulation factor II (thrombin) receptor (F2r) anticorps
  • nuclear receptor subfamily 1, group I, member 2 (NR1I2) anticorps
  • AI482343 anticorps
  • BXR anticorps
  • Cf2r anticorps
  • f2r-a anticorps
  • HTR anticorps
  • ONR1 anticorps
  • PAR anticorps
  • Par-1 anticorps
  • Par1 anticorps
  • PAR2 anticorps
  • PARq anticorps
  • PRR anticorps
  • PXR anticorps
  • SAR anticorps
  • SXR anticorps
  • ThrR anticorps
  • TR anticorps
  • TRGPC anticorps

Protein level used designations for F2R

PAR-1 , coagulation factor II (thrombin) receptor , coagulation factor II receptor , proteinase-activated receptor 1 , thrombin receptor , protease-activated receptor 1 , Thrombin receptor , protease-activated receptor-1 , nuclear receptor subfamily 1 group I member 2 , orphan nuclear receptor PAR1 , orphan nuclear receptor PXR , pregnane X nuclear receptor variant 2 , pregnane X receptor , steroid and xenobiotic receptor

378526 Xenopus laevis
2149 Homo sapiens
14062 Mus musculus
25439 Rattus norvegicus
526585 Bos taurus
100521609 Sus scrofa
8856 Homo sapiens
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