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Human Monoclonal INHBC Primary Antibody pour EIA, IP - ABIN316982
Mellor, Cranfield, Ries, Pedersen, Cancilla, de Kretser, Groome, Mason, Risbridger: Localization of activin beta(A)-, beta(B)-, and beta(C)-subunits in humanprostate and evidence for formation of new activin heterodimers of beta(C)-subunit. dans The Journal of clinical endocrinology and metabolism 2001
Show all 3 references for ABIN316982
Results showed activin (Montrer Actbeta Anticorps)-C and follistatin (Montrer FST Anticorps) are differentially expressed during prostate development and suggested that the antagonistic property of follistatin (Montrer FST Anticorps) is secondary to the action of activin (Montrer Actbeta Anticorps)-C. Study provides evidence to support a role of activin (Montrer Actbeta Anticorps)-C in prostate development and provides new insights in the spatiotemporal localization of activins and their antagonists during mouse prostate development.
Data reinforces the importance of activin (Montrer Actbeta Anticorps)-betaC in reproductive biology and suggests that activin (Montrer Actbeta Anticorps)-betaC is a tumor modulator with gonadal specificity.
Data support the conclusion that activin (Montrer Actbeta Anticorps) inhibits adrenal tumor growth promoted by luteinizing hormone by inducing adrenal x-zone regression.
results indicate that the beta(C) and beta(E) subunits of activin (Montrer Actbeta Anticorps) form homo- and heterodimers, and that the functions of the two subunits are quite different
Activin A (Montrer INHBA Anticorps), B, and AB have similar effects on steroidogenesis in human granulosa cells; in contrast, activin (Montrer Actbeta Anticorps) AC is not biologically active and does not act as a competitive antagonist.
Serum inhibin levels correlate with clinical characteristics and mortality in epithelial ovarian cancer patients.
The inhibin-betaC subunit is down-regulated, while inhibin-betaE is up-regulated by interferon (Montrer IFNA Anticorps)-beta1a in Ishikawa carcinoma cell line.
Single Nucleotide Polymorphisms in INHBC gene is associated with brain metastasis in non-small-cell lung cancer
Activin-beta (Montrer Actbeta Anticorps)(C) is a regulator of activin-A (Montrer INHBA Anticorps). Activin-beta (Montrer Actbeta Anticorps)(C) is able to abolish cachexia and modulate reproductive tumour development in inhibin alpha-subunit (Montrer INHA Anticorps) knockout mice (alpha-KO) mice.
inhibin-betaC in normal and pathological placental tissue was demonstrated, although no differences in staining intensity could be observed. Functional role of novel inhibin-betaC subunit in normal and pathological human placenta is still quite unclear.
Data show that inhibin A levels were significantly lower in the PCOS group compared to the control group, and inhibin B levels were comparable in the two groups.
the novel inhibin/activin (Montrer Actbeta Anticorps)-betaC subunit is expressed in human endometrioid adenocarcinomas and in the human endometrial carcinoma cell line HEC (Montrer NDC80 Anticorps)-1a
Expression of the inhibin betaC and betaE subunits was demonstrated at the protein level and at the transcriptional level in normal human endometrial tissue and in the Ishikawa human endometrial carcinoma cell line.
Expression of inhibin beta C was detected in the human chorionic carcinoma cell lines JEG and BeWoand also in human placenta.
This gene encodes the beta C chain of inhibin, a member of the TGF-beta superfamily. This subunit forms heterodimers with beta A and beta B subunits. Inhibins and activins, also members of the TGF-beta superfamily, are hormones with opposing actions and are involved in hypothalamic, pituitary, and gonadal hormone secretion, as well as growth and differentiation of various cell types.
inhibin, beta C
, Activin beta-C chain
, activin beta-C chain
, activin/inhibin beta C
, inhibin beta C chain