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Tumor Susceptibility Gene 101 (TSG101) (N-Term) Peptide

TSG101 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN2183454
  • Antigène Tous les produits TSG101
    TSG101 (Tumor Susceptibility Gene 101 (TSG101))
    Protein Region
    N-Term
    Origine
    Humain
    Source
    • 8
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    YKYRDLTVRE TVNVITLYKD LKPVLDSYVF NDGSSRELMN LTGTIPVPYR
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-TSG101 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    TSG101 (Tumor Susceptibility Gene 101 (TSG101))
    Synonymes
    CG9712 Peptide, DmTSG101 Peptide, Dmel\\CG9712 Peptide, ESCRT-I Peptide, Tsg101 Peptide, burs Peptide, dTSg101 Peptide, dTsg101 Peptide, dVps23 Peptide, ept Peptide, tsg101 Peptide, vps23 Peptide, TSG101 Peptide, MGC76193 Peptide, TSG10 Peptide, VPS23 Peptide, AI255943 Peptide, CC2 Peptide, Rw Peptide, zgc:86926 Peptide, tumor susceptibility 101 Peptide, Tumor susceptibility gene 101 Peptide, Tumor Susceptibility Gene homolog Peptide, tumor susceptibility gene 101 Peptide, tumor susceptibility 101a Peptide, tumor susceptibility 101 L homeolog Peptide, TSG101 Peptide, tsg-101 Peptide, tsg101 Peptide, Tsg101 Peptide, tsg101a Peptide, tsg101.L Peptide
    Sujet
    The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

    Alias Symbols: TSG10, VPS23

    Protein Size: 390
    Poids moléculaire
    44 kDa
    ID gène
    7251
    NCBI Accession
    NM_006292, NP_006283
    UniProt
    Q99816
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