Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (N-Term) Peptide
CDC25A
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits CDC25A
- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
- Protein Region
- N-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- QLQGLGSDYE QPLEVKNNSN LQRMGSSEST DSGFCLDSPG PLDSKENLEN
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CDC25A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
- Synonymes
- cdc25a2 Peptide, cdc25A Peptide, sb:cb317 Peptide, CDC25A2 Peptide, D9Ertd393e Peptide, cell division cycle 25A Peptide, cell division cycle 25B Peptide, cell division cycle 25A S homeolog Peptide, CDC25A Peptide, cdc25a Peptide, cdc25b Peptide, Cdc25a Peptide, cdc25a.S Peptide
- Sujet
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CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CDC25A2
Protein Size: 524 - Poids moléculaire
- 59 kDa
- ID gène
- 993
- NCBI Accession
- NM_001789, NP_001780
- UniProt
- P30304
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