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F-Box Protein 31 (FBXO31) (Middle Region) Peptide

FBXO31 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN976747
  • Antigène Tous les produits FBXO31
    FBXO31 (F-Box Protein 31 (FBXO31))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    QGPRESQPSP AQPRAEAPSK GPDGTPGEDG GEPGDAVAAA EQPAQCGQGQ
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-FBXO31 Antibody(ARP53775_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    FBXO31 (F-Box Protein 31 (FBXO31))
    Synonymes
    1110003O08Rik Peptide, 2310046N15Rik Peptide, Fbx14 Peptide, Fbxo14 Peptide, FBX14 Peptide, FBXO14 Peptide, Fbx31 Peptide, pp2386 Peptide, RGD1561069 Peptide, fbx14 Peptide, fbx31 Peptide, fbxo14 Peptide, fbxo31 Peptide, F-box protein 31 Peptide, F-box protein 31 S homeolog Peptide, F-box protein 31 L homeolog Peptide, Fbxo31 Peptide, FBXO31 Peptide, fbxo31 Peptide, fbxo31.S Peptide, fbxo31.L Peptide
    Sujet
    FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.

    Alias Symbols: DKFZP434B027, DKFZp434J1815, FBX14, FBXO14, FLJ22477, Fbx31, MGC15419, MGC9527, pp2386

    Protein Interaction Partner: CUL1,RBX1,SKP1

    Protein Size: 367
    Poids moléculaire
    40 kDa
    ID gène
    79791
    NCBI Accession
    NM_024735, NP_079011
    UniProt
    Q5XUX0
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