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Membrane Metallo-Endopeptidase (MME) (C-Term) Peptide

MME Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN980144
  • Antigène Tous les produits MME
    MME (Membrane Metallo-Endopeptidase (MME))
    Protein Region
    C-Term
    Origine
    Humain
    Source
    • 9
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    EYAVNSIKTD VHSPGNFRII GTLQNSAEFS EAFHCRKNSY MNPEKKCRVW
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-MME Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    MME (Membrane Metallo-Endopeptidase (MME))
    Synonymes
    CALLA Peptide, CD10 Peptide, NEP Peptide, SFE Peptide, 6030454K05Rik Peptide, C85356 Peptide, Nep Peptide, neprilysin Peptide, membrane metalloendopeptidase Peptide, membrane metallo endopeptidase Peptide, membrane metallo-endopeptidase Peptide, MME Peptide, Mme Peptide
    Classe de substances
    Chemical
    Sujet
    This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts.

    Alias Symbols: CALLA, CD10, DKFZp686O16152, MGC126681, MGC126707, NEP, SFE

    Protein Interaction Partner: ADCYAP1,ADM,CSNK2B,EDN1,EDN2,GAST,LYN,NDRG1,NPPA,NPPC,PIK3CB,PIK3R1,SHC1,VIP,ALDH3A2,ARL1,ARMC10,ATP12A,ATP5J2,CD4,CDK5RAP3,CLEC4M,CPSF6,CSNK2A1,DNAJB12,EEF1A1,FAAH,FAHD1,FAM83F,FECH,FLOT2,FOLH1,HIST1H2AG,HSPA1A,HSPA4,HSPA8,HSPB1,IMPDH2,INPP5D,IRAK2,ITFG3,KBTBD3,KRT10,LAMTOR1,LMNA,LONP1,LYN,METTL7A,MME,MRPL44,MRPS25,MRVI1,MTDH,MTHFD1,MYH9,NDUFA10,NDUFA9,NDUFB4,NNT,NOLC1,NUCKS1,OPA1,PCNA,PDIA5,POTEI,RAP2B,RBM39,RGPD6,RPL30,RPS10,RPS23,RUVBL1,RUVBL2,SDF4,SLC16A1,SLC9A3R1,SRSF11,SSR4,TM9SF1,TNPO1,TUBB8,UBAC2,UTRN,VDAC2,XRCC5,ZMPSTE24

    Protein Size: 750
    Poids moléculaire
    83 kDa
    ID gène
    4311
    NCBI Accession
    NM_007287, NP_009218
    UniProt
    P08473
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