RAD23 Homolog B (RAD23B) (Middle Region) Peptide
RAD23B
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits RAD23B
- RAD23B (RAD23 Homolog B (RAD23B))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- QSSAVAAAAA TTTATTTTTS SGGHPLEFLR NQPQFQQMRQ IIQQNPSLLP
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-RAD23B Antibody(ARP56505_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- RAD23B (RAD23 Homolog B (RAD23B))
- Synonymes
- HHR23B Peptide, HR23B Peptide, P58 Peptide, 0610007D13Rik Peptide, AV001138 Peptide, mHR23B Peptide, p58 Peptide, MGC107846 Peptide, zgc:65951 Peptide, RAD23 homolog B, nucleotide excision repair protein Peptide, UV excision repair protein RAD23 homolog B Peptide, RAD23 homolog B, nucleotide excision repair protein S homeolog Peptide, RAD23B Peptide, Rad23b Peptide, rd23b Peptide, rad23b Peptide, rad23b.S Peptide
- Sujet
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The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Alias Symbols: HHR23B, HR23B, P58
Protein Interaction Partner: ATXN3,ATXN3,MPG,NGLY1,PSMD4,PSMD4,TDG,UBB,XPC,ZFAND5,ATXN3,OTUD1,PAX3,PSMD4,UCHL5,XPC
Protein Size: 409 - Poids moléculaire
- 43 kDa
- ID gène
- 5887
- NCBI Accession
- NM_002874, NP_002865
- UniProt
- P54727
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