Transmembrane Protein 173 (TMEM173) (Middle Region) Peptide
TMEM173
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits STING/TMEM173 (TMEM173)
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- DPNIRFLDKL PQQTGDHAGI KDRVYSNSIY ELLENGQRAG TCVLEYATPL
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TMEM173 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Synonymes
- ERIS Peptide, MITA Peptide, MPYS Peptide, NET23 Peptide, STING Peptide, 2610307O08Rik Peptide, Mita Peptide, RGD1562552 Peptide, transmembrane protein 173 Peptide, TMEM173 Peptide, Tmem173 Peptide
- Sujet
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This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Alias Symbols: ERIS, MITA, MPYS, SAVI, NET23, STING, hMITA, hSTING
Protein Size: 379 - Poids moléculaire
- 42 kDa
- ID gène
- 340061
- NCBI Accession
- NM_198282, NP_938023
- UniProt
- Q86WV6
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