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Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) (Middle Region) Peptide

ZFP36 Reactivité: Humain Hôte: Synthetic BP, WB, IHC
N° du produit ABIN986434
  • Antigène Tous les produits ZFP36
    ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-ZFP36 antibody (Catalog #: ARP38304_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))
    Synonymes
    G0S24 Peptide, GOS24 Peptide, NUP475 Peptide, RNF162A Peptide, TIS11 Peptide, TTP Peptide, zfp-36 Peptide, c3h-1 Peptide, g0s24 Peptide, gos24 Peptide, nup475 Peptide, rnf162a Peptide, tis11 Peptide, ttp Peptide, ZFP36 Peptide, C3H-1 Peptide, Gos24 Peptide, Nup475 Peptide, TIS11D Peptide, TISII Peptide, Tis11 Peptide, Ttp Peptide, Zfp-36 Peptide, ZFP36 ring finger protein Peptide, ZFP36 ring finger protein L homeolog Peptide, tristetraproline Peptide, Tristetraproline Peptide, similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth Peptide, zinc finger protein 36 Peptide, ZFP36 Peptide, zfp36.L Peptide, EDI_287240 Peptide, Bm1_42085 Peptide, LOAG_03119 Peptide, zfp36 Peptide, Zfp36 Peptide
    Sujet
    ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release. Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression. Multiple phosphorylation sites in ZFP36 in mammalian cells were reported. ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family. Gene expression profiling predicts clinical outcome of prostate cancer. Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.

    Alias Symbols: G0S24, GOS24, NUP475, RNF162A, TIS11, TTP

    Protein Interaction Partner: PTGS2,tax,CCDC85B,EDC3,EXOSC6,EXOSC8,HMGB1,MAPKAPK2,NUP214,SFN,UPF2,XRN1,YWHAB,YWHAG,YWHAH,CCDC85B,NUP214,YWHAB,YWHAH

    Protein Size: 326
    Poids moléculaire
    34 kDa
    ID gène
    7538
    NCBI Accession
    NM_003407, NP_003398
    UniProt
    P26651
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