Aperçu des produits pour PLEKHA1 (PLEKHA1) Kits ELISA

Full name:
Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 Kits ELISA (PLEKHA1)
Chez www.anticorps-enligne.fr sont 0 Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 (PLEKHA1) Kits ELISA de de différents fournisseurs disponibles. De plus, nous expédions PLEKHA1 Anticorps (45) et PLEKHA1 Protéines (8) et beaucoup plus de produits pour cette protéine. Un total de 59 PLEKHA1 produits sont actuellement listés.
Synonymes:
AA960558, C920009D07Rik, DKFZp459M1025, fc34a05, fc57h12, MGC83674, PLEKHA1, RGD1564153, TAPP1, wu:fc34a05, wu:fc57h12, zgc:55676
list all ELISA KIts Gène GeneID UniProt
Rat PLEKHA1 PLEKHA1 361659  
Humain PLEKHA1 PLEKHA1 59338 Q9HB21
Souris PLEKHA1 PLEKHA1 101476 Q8BUL6

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Plus Kits ELISA pour PLEKHA1 partenaires d'interaction

Human Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 (PLEKHA1) interaction partners

  1. Studies indicate that the high-risk allele of the 10q26 locus encompasses three genes, PLEKHA1, ARMS2 (Montrer ARMS2 Kits ELISA), and HTRA1 (Montrer HTRA1 Kits ELISA) with high linkage disequilibrium.

  2. CX3CR1 (Montrer CX3CR1 Kits ELISA) (T280M and V249I) and PLEKHA1 (A320T) polymorphisms were not found to be associated with age-related macular degeneration in an Indian population.

  3. This study provides evidence of the joint contribution of genetic variants in PLEKHA1/ARMS2 (Montrer ARMS2 Kits ELISA)/HTRA1 (Montrer HTRA1 Kits ELISA) to age-related macular degeneration risk.

  4. TAPP1 binds to protein tyrosine phosphatase PTPL1 (Montrer PTPN13 Kits ELISA).

  5. syntrophins regulate the localization of TAPP1, which may be important for remodeling the actin cytoskeleton in response to growth factor stimulation

  6. PLEKHA1 is strongly implicated as primarily responsible for the evidence of linkage of age-related maculopathy (ARM) to the 10q26 locus and as a major contributor to ARM.susceptibility.

  7. Although a role for PLEKHA1 could not be totally excluded, there was a four times higher age-related macular degeneration risk was associated with haplotype "A-T-A" involving "PLEKHA1-LOC387715-HTRA1 (Montrer HTRA1 Kits ELISA)" risk alleles.

  8. Independent of CFH (Montrer CFH Kits ELISA) genotype or smoking history, an individual's risk of AMD (Montrer AMD1 Kits ELISA) (age-related macular degeneration) could be increased or decreased, depending on their genotype or haplotype in the 10q26 region.

Mouse (Murine) Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 (PLEKHA1) interaction partners

  1. this study shows that TAPP1/2 double knock-out mice develop chronic germinal centers with age and show abnormal expression of B-cell activation (Montrer BLNK Kits ELISA) anddevelop lupus-like characteristics including anti-DNA antibodies and deposition of immune complexes in kidneys

  2. Results identify TAPP1 as an important negative regulator of oligodendrocyte precursor cells differentiation through the Mek (Montrer MDK Kits ELISA)/Erk (Montrer EPHB2 Kits ELISA) signaling pathway.

  3. interacts with phosphatidylinositol (3,4)-bisphosphate thus regulating B-cell activation (Montrer BLNK Kits ELISA) and autoantibody production

PLEKHA1 profil antigène

Antigen Summary

This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.

Alternative names and synonyms associated with PLEKHA1

  • pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 (Plekha1) Elisa Kit
  • pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 (plekha1) Elisa Kit
  • pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 (PLEKHA1) Elisa Kit
  • AA960558 Elisa Kit
  • C920009D07Rik Elisa Kit
  • DKFZp459M1025 Elisa Kit
  • fc34a05 Elisa Kit
  • fc57h12 Elisa Kit
  • MGC83674 Elisa Kit
  • PLEKHA1 Elisa Kit
  • RGD1564153 Elisa Kit
  • TAPP1 Elisa Kit
  • wu:fc34a05 Elisa Kit
  • wu:fc57h12 Elisa Kit
  • zgc:55676 Elisa Kit

Protein level used designations for PLEKHA1

pleckstrin homology domain-containing family A member 1 , pleckstrin homology domain-containing protein family A member 1 , tandem PH domain containing protein-1 , pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 , tandem PH domain-containing protein 1 , PH domain-containing family A member 1 , TAPP-1

GENE ID SPECIES
361659 Rattus norvegicus
406745 Danio rerio
423940 Gallus gallus
446375 Xenopus laevis
450790 Pan troglodytes
477851 Canis lupus familiaris
513040 Bos taurus
549587 Xenopus (Silurana) tropicalis
100019790 Monodelphis domestica
100058481 Equus caballus
100174594 Pongo abelii
59338 Homo sapiens
101476 Mus musculus
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