Aperçu des produits pour SPRED1 (SPRED1) Kits ELISA

Full name:
Sprouty-Related, EVH1 Domain Containing 1 Kits ELISA (SPRED1)
Chez www.anticorps-enligne.fr sont 0 Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) Kits ELISA de de différents fournisseurs disponibles. De plus, nous expédions SPRED1 Anticorps (106) et SPRED1 Protéines (3) et beaucoup plus de produits pour cette protéine. Un total de 116 SPRED1 produits sont actuellement listés.
Synonymes:
5730461F13Rik, AL024345, AW047647, fb14c08, fj51c03, hSpred1, NFLS, spred-1, wu:fb14c08, wu:fj51c03, Xspred1, Xtspred1, zgc:85707
list all ELISA KIts Gène GeneID UniProt
Souris SPRED1 SPRED1 114715 Q924S8
Humain SPRED1 SPRED1 161742 Q7Z699
Rat SPRED1 SPRED1 296072  

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Plus Kits ELISA pour SPRED1 partenaires d'interaction

Mouse (Murine) Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) interaction partners

  1. Cosuppression of Sprouty and Sprouty-related negative regulators of FGF signalling in prostate cancer

  2. SPREDs promote self-renewal and inhibit mesodermal differentiation of murine ES cells by selective suppression of the ERK/MAPK (Montrer MAPK1 Kits ELISA) signaling pathway in pluripotent cells

  3. The data suggest that Spred1 negatively regulates group 2 innate lymphoid cell development and functions through the suppression of the Ras-ERK (Montrer EPHB2 Kits ELISA) pathway.

  4. Microrna-126 was transported into recipient human coronary artery endothelial cells by endothelial microparticles and functionally regulated the target protein sprouty-related, EVH1 domain-containing protein 1 (SPRED1).

  5. show that neurofibromin (Montrer NF1 Kits ELISA), the NF1 (Montrer NF1 Kits ELISA) gene product, is a Spred1-interacting protein that is necessary for Spred1's inhibitory function

  6. The results suggest that Spred1 negatively regulates mast cell activation, which is modulated by miR126.

  7. SPRED1 is a likely substrate of SHP2 (Montrer PTPN11 Kits ELISA), whose tyrosine dephosphorylation is required to attenuate the inhibitory action of SPRED1 in the Ras/ERK (Montrer EPHB2 Kits ELISA) pathway.

  8. Data show that both SPRED1 and SPRED2 (Montrer SPRED2 Kits ELISA) inhibit the ability of DYRK1A (Montrer DYRK1A Kits ELISA) to phosphorylate its substrates.

  9. These data suggest that Spreds are key regulators of RhoA (Montrer RHOA Kits ELISA)-mediated cell motility and signal transduction. Furthermore, our study suggests that the induction of Spreds could be a novel strategy for preventing cancer cell metastasis.

  10. Spred-1 and Spred-2 (Montrer SPRED2 Kits ELISA) were found to be expressed predominantly in brain

Human Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) interaction partners

  1. The EVH1 domain of Spred1 binds to the noncatalytic portion of the GAP-related domain of neurofibromin (Montrer NF1 Kits ELISA).

  2. Results provide genetic evidence that miR (Montrer MLXIP Kits ELISA)-126, through its target gene Spred-1, plays a critical role in the development of retinal vascular layers.

  3. In one case we identified a nonsense mutation c.46C>T (p.Arg16*) in exon 2 of SPRED1 gene, confirming diagnosis of Legius syndrome. This mutation was reported previously.

  4. PURA (Montrer PURA Kits ELISA) may be a potential target of miR (Montrer MLXIP Kits ELISA)-144 and observed downregulation of PURA (Montrer PURA Kits ELISA) may be caused by increased expression of miR (Montrer MLXIP Kits ELISA)-144. The other predicted target of miR (Montrer MLXIP Kits ELISA)-144 SPRED1, was found to be downregulated in 69 per cent EC tissues as compared to matched distant non-malignant tissues.

  5. Data suggest SPRED1 EVH1 domain interacts with NF1 (Montrer NF1 Kits ELISA) GRD domain [N-term. 16AA/C-term. 20AA of GTPase-activating protein (Montrer RASA1 Kits ELISA)-related domain]; SPRED1 EVH1 and NF1 (Montrer NF1 Kits ELISA) GRD mutations observed in Legius syndrome reduce binding affinity between EVH1/GRD domains.

  6. Cosuppression of Sprouty and Sprouty-related negative regulators of FGF signalling in prostate cancer

  7. SPRED1 decreased expression correlated with genetic features of AML (Montrer RUNX1 Kits ELISA). Our study reveals a new mechanism which contributes to deregulate RAS MAPK (Montrer MAPK1 Kits ELISA) pathway in the vast majority of paediatric AMLs

  8. Antisense-mediated knockdown (anti-miR (Montrer MLXIP Kits ELISA)) revealed that miR (Montrer MLXIP Kits ELISA)-206/21 coordinately promote RAS-ERK (Montrer EPHB2 Kits ELISA) signaling and the corresponding cell phenotypes by inhibiting translation of the pathway suppressors RASA1 (Montrer RASA1 Kits ELISA) and SPRED1.

  9. SPRED1 seems to play an important role in recruiting neurofibromin (Montrer NF1 Kits ELISA) to the plasma membrane. (Review)

  10. Older age and deletions of IKZF1 (Montrer IKZF1 Kits ELISA) and SPRED1 were also associated with poor overall survival of pediatric B-cell precursor acute lymphoblastic leukemia.

SPRED1 profil antigène

Antigen Summary

The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).

Alternative names and synonyms associated with SPRED1

  • sprouty-related, EVH1 domain containing 1 (spred1) Elisa Kit
  • sprouty-related, EVH1 domain containing 1 (SPRED1) Elisa Kit
  • SPRED1 (Bm1_51610) Elisa Kit
  • sprouty protein with EVH-1 domain 1, related sequence (Spred1) Elisa Kit
  • sprouty-related, EVH1 domain containing 1 (Spred1) Elisa Kit
  • 5730461F13Rik Elisa Kit
  • AL024345 Elisa Kit
  • AW047647 Elisa Kit
  • fb14c08 Elisa Kit
  • fj51c03 Elisa Kit
  • hSpred1 Elisa Kit
  • NFLS Elisa Kit
  • spred-1 Elisa Kit
  • wu:fb14c08 Elisa Kit
  • wu:fj51c03 Elisa Kit
  • Xspred1 Elisa Kit
  • Xtspred1 Elisa Kit
  • zgc:85707 Elisa Kit

Protein level used designations for SPRED1

sprouty-related, EVH1 domain-containing protein 1 , sprouty-related protein with EVH-1 domain 1 , sprouty-related, EVH1 domain containing 1 , spred-1 , sprouty-related, EVH1 domain-containing protein 1-like , SPRED1 , sprouty-related protein 1 with EVH-1 domain , suppressor of Ras/MAPK activation , sprouty protein with EVH-1 domain 1, related sequence

GENE ID SPECIES
406513 Danio rerio
423292 Gallus gallus
467654 Pan troglodytes
487485 Canis lupus familiaris
493399 Xenopus (Silurana) tropicalis
519882 Bos taurus
100057517 Equus caballus
100158360 Xenopus laevis
100512576 Sus scrofa
100563315 Anolis carolinensis
6105207 Brugia malayi
100351685 Oryctolagus cuniculus
100391851 Callithrix jacchus
100482511 Ailuropoda melanoleuca
100544962 Meleagris gallopavo
100583864 Nomascus leucogenys
114715 Mus musculus
161742 Homo sapiens
296072 Rattus norvegicus
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