Caspase 1 Protein (CASP1) (AA 120-269, partial) (GST tag)
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- Antigène Voir toutes Caspase 1 (CASP1) Protéines
- Caspase 1 (CASP1)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 120-269, partial
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Caspase 1 protéine est marqué à la GST tag.
- Application
- ELISA
- Séquence
- NPAMPTSSGS EGNVKLCSLE EAQRIWKQKS AEIYPIMDKS SRTRLALIIC NEEFDSIPRR TGAEVDITGM TMLLQNLGYS VDVKKNLTAS DMTTELEAFA HRPEHKTSDS TFLVFMSHGI REGICGKKHS EQVPDILQLN AIFNMLNTKN
- Attributs du produit
- Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
- Pureté
- 90 %
- Top Product
- Discover our top product CASP1 Protéine
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- Commentaires
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The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- 0.2-2 mg/mL
- Buffer
- Tris-based buffer, 50 % glycerol
- Conseil sur la manipulation
- Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
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Purification and characterization of active human interleukin-1 beta-converting enzyme from THP.1 monocytic cells." dans: The Journal of biological chemistry, Vol. 268, Issue 24, pp. 18062-9, (1993) (PubMed).
: "A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes." dans: Nature, Vol. 356, Issue 6372, pp. 768-74, (1992) (PubMed).
: "Molecular cloning of the interleukin-1 beta converting enzyme." dans: Science (New York, N.Y.), Vol. 256, Issue 5053, pp. 97-100, (1992) (PubMed).
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Purification and characterization of active human interleukin-1 beta-converting enzyme from THP.1 monocytic cells." dans: The Journal of biological chemistry, Vol. 268, Issue 24, pp. 18062-9, (1993) (PubMed).
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- Antigène
- Caspase 1 (CASP1)
- Autre désignation
- Caspase-1 protein (CASP1 Produits)
- Sujet
- Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
- Poids moléculaire
- 44.2 kD
- UniProt
- P29466
- Pathways
- Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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