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IL-8 Protein (AA 23-99) (His tag)

IL8 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 85% (SDS-PAGE) ELISA
N° du produit ABIN1047264
  • Antigène Voir toutes IL-8 (IL8) Protéines
    IL-8 (IL8) (Interleukin 8 (IL8))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 23-99
    Origine
    • 36
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 44
    • 14
    • 10
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette IL-8 protéine est marqué à la His tag.
    Application
    ELISA
    Séquence
    AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS
    Attributs du produit
    Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
    Pureté
    > 85% (SDS-PAGE)
    Top Product
    Discover our top product IL8 Protéine
  • Commentaires

    The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%.
    Concentration
    0.2-2 mg/mL
    Buffer
    10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0
    Conseil sur la manipulation
    Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
  • Schröder: "Biochemical and biological characterization of NAP-1/IL-8-related cytokines in lesional psoriatic scale." dans: Advances in experimental medicine and biology, Vol. 305, pp. 97-107, (1992) (PubMed).

    Van Damme, Rampart, Conings, Decock, Van Osselaer, Willems, Billiau: "The neutrophil-activating proteins interleukin 8 and beta-thromboglobulin: in vitro and in vivo comparison of NH2-terminally processed forms." dans: European journal of immunology, Vol. 20, Issue 9, pp. 2113-8, (1990) (PubMed).

  • Antigène
    IL-8 (IL8) (Interleukin 8 (IL8))
    Autre désignation
    Interleukin-8 protein (IL8 Produits)
    Synonymes
    CXCL8 Protein, GCP-1 Protein, GCP1 Protein, LECT Protein, LUCT Protein, LYNAP Protein, MDNCF Protein, MONAP Protein, NAF Protein, NAP-1 Protein, NAP1 Protein, IL-8 Protein, AMCF-I Protein, il8 Protein, IL8 Protein, si:dkey-151b16.2 Protein, cxcli2 Protein, cxcl8 Protein, gcp-1 Protein, il-8 Protein, lynap Protein, mdncf Protein, monap Protein, nap-1 Protein, C-X-C motif chemokine ligand 8 Protein, interleukin 8 Protein, chemokine (C-X-C motif) ligand 8a Protein, chemokine (C-X-C motif) ligand 1-like Protein, chemokine (C-X-C motif) ligand 8 L homeolog Protein, CXCL8 Protein, il8 Protein, cxcl8a Protein, IL8 Protein, Cxcl8 Protein, LOC422654 Protein, cxcl8.L Protein
    Sujet
    IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
    Poids moléculaire
    13 kDa
    UniProt
    P10145
    Pathways
    Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
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