PDE4D Protein (AA 1-518) (GST tag)

N° du produit ABIN1782353

Détail du produit

Antigène: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Type de proteíne: Recombinant

Attributs du protein: AA 1-518

Origine: Humain

Source: Wheat germ

Purification/Conjugué: Cette PDE4D protéine est marqué à la GST tag.

Application: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Fonction: PDE4D (Human) Recombinant Protein (P01)

Séquence: MPEANYLLSV SWGYIKFKRM LNRELTHLSE MSRSGNQVSE FISNTFLDKQ HEVEIPSPTQ KEKEKKKRPM SQISGVKKLM HSSSLTNSSI PRFGVKTEQE DVLAKELEDV NKWGLHVFRI AELSGNRPLT VIMHTIFQER DLLKTFKIPV DTLITYLMTL EDHYHADVAY HNNIHAADVV QSTHVLLSTP ALEAVFTDLE ILAAIFASAI HDVDHPGVFN QFLINTNSEL ALMYNDSSVL ENHHLAVGFK LLQEENCDIF QNLTKKQRQS LRKMVIDIVL ATDMSKHMNL LADLKTMVET KKVTSSGVLL LDNYSDRIQV LQNMVHCADL SNPTKPLQLY RQWTDRIMEE FFRQGDRERE RGMEISPMCD KHNASVEKSQ VGFIDYIVHP LWETWADLVH PDAQDILDTL EDNREWYQST IPQSPSPAPD DPEEGRQGQT EKFQFELTLE EDGESDTEKD SGSQVEEDTS CSDSKTLCTQ DSESTEIPLD EQVEEEAVGE EEESQPEACV IDDRSPDT

Attributs du produit: Human PDE4D full-length ORF ( AAH36319, 1 a.a. - 518 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Stockage

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -80 °C

Stockage commentaire: Best use within three months from the date of receipt of this protein.

Référence

Branham, Bustos, De Blas, Rehmann, Zarelli, Treviño, Darszon, Mayorga, Tomes: "Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis." dans: The Journal of biological chemistry, Vol. 284, Issue 37, pp. 24825-39, (2009) (PubMed).

Branham, Mayorga, Tomes: "Calcium-induced acrosomal exocytosis requires cAMP acting through a protein kinase A-independent, Epac-mediated pathway." dans: The Journal of biological chemistry, Vol. 281, Issue 13, pp. 8656-66, (2006) (PubMed).

Détail du antigène

Antigène: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Autre désignation: PDE4D (PDE4D Produits)

Synonymes: ACRDYS2 Protein, DPDE3 Protein, HSPDE4D Protein, PDE43 Protein, PDE4DN2 Protein, STRK1 Protein, CMYA2 Protein, MMGL Protein, 9630011N22Rik Protein, Dpde3 Protein, 4732458A06Rik Protein, 9430063L05Rik Protein, C87016 Protein, D130016K21Rik Protein, D3Bwg1078e Protein, Usmg4 Protein, mKIAA0454 Protein, si:dkey-190g11.2 Protein, phosphodiesterase 4D Protein, phosphodiesterase 4D interacting protein Protein, phosphodiesterase 4D, cAMP specific Protein, phosphodiesterase 4D, cAMP-specific Protein, phosphodiesterase 4D interacting protein (myomegalin) Protein, PDE4D Protein, PDE4DIP Protein, pde4d Protein, Pde4dip Protein, Pde4d Protein

Sujet: Full Gene Name: phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)
Synonyms: DPDE3,HSPDE4D,PDE4DN2,STRK1

ID gène: 5144

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling