NAMPT Protein (AA 1-491) (His tag)
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- Antigène Voir toutes NAMPT Protéines
- NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 1-491
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Origine
- Souris
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette NAMPT protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Réactivité croisée
- Souris
- Attributs du produit
- Mouse Nampt (visfatin/PBEF) (aa 1-491) is fused at the C-terminus to a His-tag.
- Pureté
- >90 % (SDS-PAGE)
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- <1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product NAMPT Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Shows adipogenic effects in stimulated differentiating 3T3-L1 cells.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in distilled water.
- Concentration
- Lot specific
- Buffer
- Lyophilized from 0.2μm-filtered solution in PBS, pH 7.2.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - Date de péremption
- 3 months
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Visfatin regulates insulin secretion, insulin receptor signalling and mRNA expression of diabetes-related genes in mouse pancreatic beta-cells." dans: Journal of molecular endocrinology, Vol. 44, Issue 3, pp. 171-8, (2010) (PubMed).
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Visfatin regulates insulin secretion, insulin receptor signalling and mRNA expression of diabetes-related genes in mouse pancreatic beta-cells." dans: Journal of molecular endocrinology, Vol. 44, Issue 3, pp. 171-8, (2010) (PubMed).
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- Antigène
- NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))
- Autre désignation
- Nampt (Visfatin/PBEF) (NAMPT Produits)
- Sujet
- Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
- Poids moléculaire
- ~52kDa (SDS-PAGE)
- UniProt
- Q99KQ4
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