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Stathmin 1 Protein (STMN1) (AA 2-149) (His tag)

STMN1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >92 % as determined by SDS-PAGE.
N° du produit ABIN2181791
  • Antigène Voir toutes Stathmin 1 (STMN1) Protéines
    Stathmin 1 (STMN1)
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 2-149
    Origine
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 7
    • 4
    • 3
    • 2
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette Stathmin 1 protéine est marqué à la His tag.
    Séquence
    AA 2-149
    Attributs du produit
    This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 18.1 kDa. The protein migrates as 17-20 kDa under reducing (R) condition (SDS-PAGE).
    Pureté
    >92 % as determined by SDS-PAGE.
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product STMN1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Conseil sur la manipulation
    Please avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Antigène
    Stathmin 1 (STMN1)
    Autre désignation
    Stathmin 1 (STMN1 Produits)
    Synonymes
    C1orf215 Protein, LAP18 Protein, Lag Protein, OP18 Protein, PP17 Protein, PP19 Protein, PR22 Protein, SMN Protein, 19k Protein, Lap18 Protein, Op18 Protein, P18 Protein, P19 Protein, Pig Protein, Pp17 Protein, Pp18 Protein, Pp19 Protein, Pr22 Protein, Smn Protein, prosolin Protein, op18 Protein, stathmin Protein, stmn1 Protein, stmn1a Protein, lag Protein, lap18 Protein, pp17 Protein, pp19 Protein, pr22 Protein, smn Protein, fj43c10 Protein, wu:fj38b07 Protein, wu:fj43c10 Protein, zgc:110159 Protein, cb959 Protein, wu:fb14e04 Protein, zgc:136942 Protein, stmn1-a Protein, stmn1b Protein, xo35 Protein, stathmin 1 Protein, stathmin 1 S homeolog Protein, stathmin 1b Protein, stathmin 1a Protein, stathmin-like Protein, stathmin Protein, stathmin 1 L homeolog Protein, STMN1 Protein, Stmn1 Protein, stmn1.S Protein, stmn1 Protein, stmn1b Protein, stmn1a Protein, LOC100229194 Protein, stmn1.L Protein
    Sujet
    Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain. The function of STMN1 as an important regulatory protein of microtubule dynamics has been well-characterized. Stathmin (STMN1) interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathmin-like domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes non-polymerizable. Without tubulin polymerization, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends.
    Poids moléculaire
    18.1 kDa
    NCBI Accession
    NP_981946
    Pathways
    Signalisation MAPK, Dynamique des Microtubules
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