FOXO3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2712289

Détail du produit

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette FOXO3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human FOXO3 / FKHRL1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Thompson, Larson, Vidrine, Barrios, Navarro, Meyers, Simms, Prajapati, Chitsike, Hellman, Baker, Watkins: "FOXO3-NF-κB RelA Protein Complexes Reduce Proinflammatory Cell Signaling and Function." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 12, pp. 5637-47, (2015) (PubMed).

Détail du antigène

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Autre désignation: Foxo3,fkhrl1 (FOXO3 Produits)

Synonymes: AF6q21 Protein, FKHRL1 Protein, FKHRL1P2 Protein, FOXO2 Protein, FOXO3A Protein, zgc:92176 Protein, wu:fb50g02 Protein, wu:fi33f07 Protein, Fkhrl1 Protein, Foxo3a Protein, FoxO3A Protein, 1110048B16Rik Protein, 2010203A17Rik Protein, C76856 Protein, Fkhr2 Protein, FOXO-3 Protein, FOXO3 Protein, foxo3a Protein, xfoxo3 Protein, foxO3 Protein, foxO Protein, fkhr Protein, foxo5 Protein, wu:fj65a12 Protein, zFkhr Protein, forkhead box O3 Protein, forkhead box O3A Protein, forkhead box O3 L homeolog Protein, forkhead box O3b Protein, FOXO3 Protein, foxo3a Protein, Foxo3 Protein, foxo3.L Protein, foxo3 Protein, foxO3 Protein, foxo3b Protein

Sujet: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

Poids moléculaire: 71.1 kDa

NCBI Accession: NP_001446

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis