Diazepam Binding Inhibitor Protein (DBI) (AA 1-87) (His tag)
Aperçu rapide pour Diazepam Binding Inhibitor Protein (DBI) (AA 1-87) (His tag) (ABIN667004)
Antigène
Voir toutes Diazepam Binding Inhibitor (DBI) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- AA 1-87
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Purification/Conjugué
- Cette Diazepam Binding Inhibitor protéine est marqué à la His tag.
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Séquence
- MSQAEFEKAA EEVRHLKTKP SDEEMLFIYG HYKQATVGDI NTERPGMLDF TGKAKWDAWN ELKGTSKEDA MKAYINKVEE LKKKYGI
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Attributs du produit
- ACBP, 1-87aa, Human, His tag, E.coli
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Purification
- > 95% by SDS-PAGE
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 8.0) containing 0.1M NaCl, 10 % glycerol
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Conseil sur la manipulation
- Avoid repeated freezing and thawing cycles
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Diazepam Binding Inhibitor (DBI)
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Autre désignation
- ACBP/DBI
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Sujet
- ACBP, also known as ACBD1, is a diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. Expression of ACBP is significantly induced during adipocyte differentiation. ACBP is a target for proliferator-activated receptor (PPAR) gamma, and is directly activated by PPARgamma/RXRalpha and PPARalpha/RXRalpha, but not by PPARdelta/RXRalpha. Recombinant human ACBP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
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Poids moléculaire
- 12.2 kDa (107aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_001073331
Antigène
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