Aperçu des produits pour anti-EGR1 (EGR1) Anticorps

Full name:
anti-Early Growth Response 1 Anticorps (EGR1)
Chez www.anticorps-enligne.fr sont 132 Early Growth Response 1 (EGR1) Anticorps de 24 de différents fournisseurs disponibles. De plus, nous expédions EGR1 Kits (45) et EGR1 Protéines (19) et beaucoup plus de produits pour cette protéine. Un total de 204 EGR1 produits sont actuellement listés.
Synonymes:
A530045N19Rik, at225, egr, egr-1, EGR-1-A, EGR1, ETR103, g0s30, Krox-1, krox-24, krox24, Ngf1, NGF1-A, Ngfi, ngfi-a, NGFIA, tis8, wu:fj64b05, wu:fq25f01, Xegr-1, zenk, Zfp-6, zif-268, Zif268, znf225

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anti-EGR1 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal EGR1 Primary Antibody pour IHC, WB - ABIN2779517 : Yu, de Belle, Liang, Adamson: Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses. dans Molecular cell 2004 (PubMed)
    Show all 8 references for 2779517

  2. Human Monoclonal EGR1 Primary Antibody pour IF, WB - ABIN393945 : Kim, Jeong, Jeong, Kim, Lee, Shin, Kye, Son: Cigarette smoke-induced Egr-1 represses T beta R-II expression in human skin dermal fibroblasts. dans Toxicology 2010 (PubMed)
    Show all 5 references for 393945

  3. Human Monoclonal EGR1 Primary Antibody pour WB - ABIN394244 : Xu, Toure, Qu, Lin, Song, Shen, Rosario, Garcia, Schmidt, Yan: Advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling and up-regulation of Egr-1 in hypoxic macrophages. dans The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for 394244

  4. Human Monoclonal EGR1 Primary Antibody pour ELISA, WB - ABIN969092 : Chan, Lee, Ho, Wong, Lam, Tang, Chan, Abdullah, Wong, Lam: High-level expression of early growth response-1 and association of polymorphism with total IgE and atopy in allergic rhinitis adults. dans Clinica chimica acta; international journal of clinical chemistry 2009 (PubMed)
    Show all 2 references for 969092

  5. Human Polyclonal EGR1 Primary Antibody pour FACS, IF - ABIN389442 : Zhang, Chen, Wang, Guang, Han, Zhang, Tan, Gu: EGR1 decreases the malignancy of human non-small cell lung carcinoma by regulating KRT18 expression. dans Scientific reports 2014 (PubMed)
    Show all 2 references for 389442

  6. Cow (Bovine) Polyclonal EGR1 Primary Antibody pour IHC, WB - ABIN2779828 : Schnell, Zoller, Patel, Williams, Kersh: Early growth response gene 1 provides negative feedback to inhibit entry of progenitor cells into the thymus. dans Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

  7. Cow (Bovine) Polyclonal EGR1 Primary Antibody pour WB - ABIN2774222 : Akutagawa, Nishi, Kyo, Terauchi, Yamazawa, Higuma, Inoue, Isaka: Early growth response-1 mediates downregulation of telomerase in cervical cancer. dans Cancer science 2008 (PubMed)

Plus d’anticorps contre EGR1 partenaires d’interaction

Pig (Porcine) Early Growth Response 1 (EGR1) interaction partners

  1. Egr-1 silencing through intracoronary delivery of a targeting DNAzyme at the time of reperfusion following acute myocardial ischemia decreases myocardial inflammation and apoptosis leading to improved cardiac function.

  2. Intracoronary delivery of DNAzymes targeting human EGR-1 reduces infarct size following myocardial ischaemia reperfusion.

  3. Data suggest that Egr-1 protein levels may be tightly regulated in an attempt to diminish neurotoxicity or to enhance plasticity in newborn animals.

Human Early Growth Response 1 (EGR1) interaction partners

  1. Finally, the authors show that EGFR (Montrer EGFR Anticorps)-ERK1/2 (Montrer MAPK1/3 Anticorps) and beta1-integrin signaling are the main pathways used for bacteria-mediated EGR1 upregulation.

  2. Early growth response (Egr)-1 is essential for fibrotic responses to Transforming growth factor (TGF)-beta (Montrer TGFB1 Anticorps). Egr-1 mediates TGF-beta1 (Montrer TGFB1 Anticorps)-induced COL1A1 (Montrer COL1A1 Anticorps) and COL1A2 (Montrer COL1A2 Anticorps) mRNA expression and acid-soluble collagen production in buccal mucosal fibroblasts (BMFs).The epigallocatechin-3-gallate (EGCG) can block TGF-beta1 (Montrer TGFB1 Anticorps)-induced collagen production by attenuating Egr-1 expression in BMFs.

  3. Along with the reduction of ovarian cancer-2/disabled homolog 2 (DOC-2 (Montrer DAB2 Anticorps)/DAB2) interactive protein (DAB2IP (Montrer DAB2IP Anticorps)) expression, EGR-1 gene was upregulated in FI-treated cells. On the other hand, downregulation of EGR-1 gene expression sensitized radioresistant cells to IR accompanied by DAB2IP (Montrer DAB2IP Anticorps) overexpression and STAT3 (Montrer STAT3 Anticorps) inactivation. In addition, NF-kappaB (Montrer NFKB1 Anticorps) inhibitor, BAY11-7082 enhanced resistant cells' radiosensitivity and chemos...

  4. ROS (Montrer ROS1 Anticorps) activation of the MAPK (ERK (Montrer MAPK1 Anticorps)-1 (Montrer MAPK3 Anticorps)/2)/Egr-1 pathway is a main player in the regulatory mechanism for cigarette smoke extract-induced PlGF (Montrer PGF Anticorps) production. Antioxidants could partly abolish these effects.

  5. adipose tissue-derived mesenchymal stem cells (AT-MSCs) from diabetic patients may contribute to microvascular damage and delay wound healing through the overexpression of EGR-1.

  6. KLF12 (Montrer KLF12 Anticorps) promotes tumor growth by directly activating early growth response protein 1 (EGR1). The levels of KLF12 (Montrer KLF12 Anticorps) and EGR1 correlate synergistically with a poor prognosis. These results indicate that KLF12 (Montrer KLF12 Anticorps) likely plays an important role in CRC (Montrer CALR Anticorps) and could serve as a potential prognostic marker and therapeutic target.

  7. Shikonin induces apoptosis in some lung cancer cells via activation of FOXO3a (Montrer FOXO3 Anticorps)/EGR1/SIRT1 (Montrer SIRT1 Anticorps) signaling, and AKT (Montrer AKT1 Anticorps) and p300 (Montrer EP300 Anticorps) negatively regulate this process via Bim (Montrer BCL2L11 Anticorps) upregulation.

  8. Inhibition of mTORC1-mediated 4EBP1 (Montrer EIF4EBP1 Anticorps) phosphorylation leads to decreased expression of c-MYC (Montrer MYC Anticorps) and subsequent upregulation of the proapoptotic BCL2 (Montrer BCL2 Anticorps) family member PUMA (Montrer BBC3 Anticorps), whereas inhibition of mTORC2 (Montrer CRTC2 Anticorps) results in nuclear factor-kappaB-mediated expression of the Early Growth Response 1 (EGR1) gene, which encodes a transcription factor that binds and transactivates the proapoptotic BCL2L11 (Montrer BCL2L11 Anticorps) locus encoding BIM (Montrer BCL2L11 Anticorps).

  9. Conversely, siRNA-mediated Klotho (Montrer KL Anticorps) silencing up-regulated Egr-1, FN, and Col (Montrer HDAC1 Anticorps) I expression and the p-Smad3/Smad3 (Montrer SMAD3 Anticorps) ratio. Moreover, the effects of si-Klotho (Montrer KL Anticorps) on Egr-1 expression were abolished by the TGF-beta1 (Montrer TGFB1 Anticorps) inhibitor SB-431542. Klotho (Montrer KL Anticorps) overexpression can prevent mesangial ECM (Montrer MMRN1 Anticorps) production in high-glucose-treated human MCs (Montrer SMCP Anticorps), an effect that has been partially attributed to Egr-1 down-regulation facilitated by TGF-beta1 (Montrer TGFB1 Anticorps)/Smad3 (Montrer SMAD3 Anticorps) s...

  10. ZHX1 (Montrer ZHX1 Anticorps) was found to play essential roles in the proliferation, migration, and invasion of cholangiocarcinoma cells, and its effect on the proliferation was mediated partially through EGR1.

Cow (Bovine) Early Growth Response 1 (EGR1) interaction partners

  1. Chronic hypoxia induces Egr-1 via activation of ERK1/2 (Montrer MAPK1/3 Anticorps) and contributes to pulmonary vascular remodeling.

  2. The authors conclude that Egr-1 protein expression is very sensitive to upregulation by hypoxia in pulmonary artery adventitial fibroblasts and that it plays an important role in the autonomous growth phenotype induced by hypoxia in these cells.

  3. EGR-1's expression prior to ovulation and its stimulating effect on the expression of genes known to be involved in prostaglandin biosynthesis pathway, suggest its potential involvement in the regulation of preovulatory events in cattle.

Mouse (Murine) Early Growth Response 1 (EGR1) interaction partners

  1. Herein, we report that silencing of Egr-1 in the hippocampus by shRNA reduces tau phosphorylation, lowers amyloid-beta (Abeta (Montrer APP Anticorps)) pathology, and improves cognition in the 3xTg-Alzheimer disease mouse model.

  2. Egr-1 is a novel regulator of drebrin (Montrer DBN1 Anticorps) expression, which is linked to changes in dendritic spine density

  3. In the present study, we have investigated the contribution of element C to Krox20 (Montrer EGR2 Anticorps) expression, as it was the only characterized initiator element with an activity in r3. Using a conditional knock-out mutation of element C, we show that, unexpectedly, this element is not necessary for Krox20 (Montrer EGR2 Anticorps) initial expression in r3.

  4. HAS2 (Montrer HAS2 Anticorps)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1 (Montrer MAPK3 Anticorps)/EGR1 signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (Montrer TGFB1 Anticorps)-stimulated CD44V6/ERK (Montrer EPHB2 Anticorps)/EGR1 signaling.

  5. Egr1 expression is sensitive to mechanical signals in tendon cells.

  6. age-related up-regulation of EGR1 promotes granulosa cell apoptosis in follicle atresia during ovarian aging.

  7. data indicate that Egr-1 promotes Abeta (Montrer APP Anticorps) synthesis via transcriptional activation of BACE-1 (Montrer BACE Anticorps) and suggest that Egr-1 plays role in activation of BACE-1 (Montrer BACE Anticorps) and acceleration of Abeta (Montrer APP Anticorps) synthesis in AD brain.

  8. EGR1, an early growth response factor, is a critical transcription factor that regulates the hepatic clock circuit.

  9. EGR1(-/-) mouse embryonic fibroblasts demonstrated lower susceptibility to Venezuelan equine encephalitis virus-induced cell death than isogenic wild-type fibroblasts, indicating that EGR1 modulates proapoptotic pathways following virus infection.

  10. The levels of B23 (Montrer NPM1 Anticorps) expression are directly regulated by EGR1.

Zebrafish Early Growth Response 1 (EGR1) interaction partners

  1. egr1 colocalizes with tyrosine hydroxylase (Montrer TH Anticorps) in the olfactory bulb throughout brain development.

  2. successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish

  3. The cDNA coding for zebrafish Egr1 was obtained and its expression pattern was examined during zebrafish embryogenesis using whole-mount in situ hybridization

  4. Egr1 gene has important role in zebrafish embryonic oculogenesis. Lens and retina with egr1 gene deletion were primitive and lacked differentiation. Such arrested retinal and lenticular development in Egr1 morphants resulted in microphthalmos.

Rabbit Early Growth Response 1 (EGR1) interaction partners

  1. Gene therapy using in vivo transfection of an Egr-1 decoy ODN significantly inhibits proliferation of VSMC and intimal hyperplasia of vein grafts in a rabbit model.

  2. Results show that EGR1 plays a key role in tendon formation, healing, and repair through BMP12 (Montrer GDF7 Anticorps)/Smad1 (Montrer SMAD1 Anticorps)/5/8 pathway.

  3. Collectively, these results demonstrate that Egr-1 is expressed rapidly upon HSV-1 infection and that this novel induction could be due to the NFsmall ka, CyrillicB/CREB (Montrer CREB1 Anticorps)-mediated transactivation.

EGR1 profil antigène

Antigen Summary

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.

Alternative names and synonyms associated with EGR1

  • early growth response protein 1(Egr-1, NGFI-A) (EGR-1) anticorps
  • early growth response protein 1 (egr-1) (CNK00890) anticorps
  • early growth response 1 (EGR1) anticorps
  • early growth response 1 (Egr1) anticorps
  • early growth response 1 (egr1) anticorps
  • early growth response 1 (egr1-a) anticorps
  • early growth response protein 1 (EGR-1) anticorps
  • A530045N19Rik anticorps
  • at225 anticorps
  • egr anticorps
  • egr-1 anticorps
  • EGR-1-A anticorps
  • EGR1 anticorps
  • ETR103 anticorps
  • g0s30 anticorps
  • Krox-1 anticorps
  • krox-24 anticorps
  • krox24 anticorps
  • Ngf1 anticorps
  • NGF1-A anticorps
  • Ngfi anticorps
  • ngfi-a anticorps
  • NGFIA anticorps
  • tis8 anticorps
  • wu:fj64b05 anticorps
  • wu:fq25f01 anticorps
  • Xegr-1 anticorps
  • zenk anticorps
  • Zfp-6 anticorps
  • zif-268 anticorps
  • Zif268 anticorps
  • znf225 anticorps

Protein level used designations for EGR1

early growth response protein 1(Egr-1, NGFI-A) , early growth response protein 1 (egr-1) , early growth response 1 , EGR-1 , early growth response protein 1 , nerve growth factor-induced protein A , transcription factor ETR103 , transcription factor Zif268 , zinc finger protein 225 , zinc finger protein Krox-24 , Krox-24 nuclear protein , zinc finger protein ZENK , etID309970.14 , zinc-finger transcriptional protein , early growth response protein 1-A

GENE ID SPECIES
397332 Sus scrofa
3254484 Cryptococcus neoformans var. neoformans JEC21
100618969 Monodelphis domestica
1958 Homo sapiens
481528 Canis lupus familiaris
407125 Bos taurus
13653 Mus musculus
24330 Rattus norvegicus
462097 Pan troglodytes
100716298 Cavia porcellus
100520726 Sus scrofa
373931 Gallus gallus
443547 Ovis aries
30498 Danio rerio
100008579 Taeniopygia guttata
399162 Xenopus laevis
100009491 Oryctolagus cuniculus
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