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anti-Mouse (Murine) Tumor Protein p73 Anticorps:
anti-Human Tumor Protein p73 Anticorps:
anti-Rat (Rattus) Tumor Protein p73 Anticorps:
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Human Monoclonal Tumor Protein p73 Primary Antibody pour ChIP, CyTOF - ABIN4343232
Shimodaira, Yoshioka-Yamashita, Kolodner, Wang: Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin. dans Proceedings of the National Academy of Sciences of the United States of America 2003
Show all 49 Pubmed References
Human Monoclonal Tumor Protein p73 Primary Antibody pour ChIP, ICC - ABIN252619
Costanzo, Merlo, Pediconi, Fulco, Sartorelli, Cole, Fontemaggi, Fanciulli, Schiltz, Blandino, Balsano, Levrero: DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes. dans Molecular cell 2002
Show all 27 Pubmed References
Human Polyclonal Tumor Protein p73 Primary Antibody pour IHC (p), IP - ABIN151880
Levy, Adamovich, Reuven, Shaul: The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73. dans Cell death and differentiation 2007
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Human Monoclonal Tumor Protein p73 Primary Antibody pour IP, WB - ABIN967629
Jost, Marin, Kaelin: p73 is a simian [correction of human] p53-related protein that can induce apoptosis. dans Nature 1997
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Human Monoclonal Tumor Protein p73 Primary Antibody pour IP, WB - ABIN967628
Zhu, Jiang, Zhou, Chen: The potential tumor suppressor p73 differentially regulates cellular p53 target genes. dans Cancer research 1998
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Human Monoclonal Tumor Protein p73 Primary Antibody pour IP, WB - ABIN967630
De Laurenzi, Costanzo, Barcaroli, Terrinoni, Falco, Annicchiarico-Petruzzelli, Levrero, Melino: Two new p73 splice variants, gamma and delta, with different transcriptional activity. dans The Journal of experimental medicine 1998
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Human Monoclonal Tumor Protein p73 Primary Antibody pour WB - ABIN252620
Shao, Tanaka, Gribi, Yu: Thioredoxin-related regulation of NO/NOS activities. dans Annals of the New York Academy of Sciences 2002
Human Monoclonal Tumor Protein p73 Primary Antibody pour GS, ICC - ABIN269466
King, Reddi, Ponnamperuma, Gerdes, Weinberg: Dysregulated ΔNp63α negatively regulates the maspin promoter in keratinocytes via blocking endogenous p73 binding. dans Molecular carcinogenesis 2014
Human Polyclonal Tumor Protein p73 Primary Antibody pour IHC - ABIN966779
Yuan, Shioya, Ishiko, Sun, Gu, Huang, Lu, Kharbanda, Weichselbaum, Kufe: p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. dans Nature 1999
New function of p73 (Montrer ARHGAP24 Anticorps), independent of p53 (Montrer TP53 Anticorps), in the neurogenic architecture of the SVZ of rodent brain.
these results therefore highlight an unanticipated role for p53 (Montrer TP53 Anticorps) family proteins in a regulatory network that integrates essential Wnt (Montrer WNT2 Anticorps)-Tcf (Montrer HNF4A Anticorps) and nodal-Smad (Montrer SMAD1 Anticorps) inputs.
TAp73 as necessary and sufficient for basal body docking, axonemal extension, and motility during the differentiation of Motile multiciliated cell progenitors.
p73 (Montrer ARHGAP24 Anticorps) drives multiciliogenesis, both through transcriptional activation of a master ciliogenesis transcription factor FoxJ1 (Montrer FOXJ1 Anticorps) and through regulation of multiple genes central to ciliogenesis.
The p73 (Montrer ARHGAP24 Anticorps) acts as a critical regulator of multiciliogenesis in its capacity as a sequence-specific transcription factor, through genomic binding and regulation of genes.
Data show that the Mdm4 (Montrer MDM4 Anticorps)-p73 (Montrer ARHGAP24 Anticorps) axis cannot override the dominant role of p53 (Montrer TP53 Anticorps) in development and tumorigenesis and that Mdm4 (Montrer MDM4 Anticorps) and p73 (Montrer ARHGAP24 Anticorps) interaction during development and tumorigenesis suggests new insight into the role of p53 (Montrer TP53 Anticorps) family members.
In vivo inhibition of both p63 (Montrer CKAP4 Anticorps) and p73 (Montrer ARHGAP24 Anticorps) in combination accelerates tumor regression and increases survival of p53 (Montrer TP53 Anticorps)-deficient mice.
Results indicate that p73 (Montrer ARHGAP24 Anticorps) regulates basal and starvation-induced fuel metabolism in the liver, a finding that is likely to be highly relevant for metabolism-associated disorders, such as diabetes and cancer.
MDM2 (Montrer MDM2 Anticorps) mediates p73 (Montrer ARHGAP24 Anticorps) ubiquitination
p73 (Montrer ARHGAP24 Anticorps) is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF (Montrer VEGFA Anticorps) and TGFbeta (Montrer TGFB1 Anticorps) signaling
The reduction of tumor protein p63 (Montrer TP63 Anticorps) and tumor protein p73 isoforms, rather than alteration of DeltaN isoform expression, exerted a significant functional repercussion on cell death and proliferation in hepatitis B virus -expressing HepB cells.
p73 is epigenetically silenced in chondrosarcoma due to promoter methylation, which suggests the utility of p73 methylation as a biomarker.
A considerable number of lymphoma patients lacked the expression of either or both isoforms, while all lymphoid leukemia patients expressed both isoforms. The expression pattern differences of p73 isoforms may reflect differences in the biology of these malignancies.
TAp73beta upregulates pro-IL-1beta (Montrer IL1B Anticorps) mRNA and processed IL-1beta (Montrer IL1B Anticorps) protein. In addition, analysis of breast and lung cancer patient cohorts demonstrated that interaction between p73 and IL-1beta (Montrer IL1B Anticorps) predicts a negative survival outcome in these cancers.
analysis of how trifluoroethanol induces a conformational transition in the C-terminal sterile alpha motif (SAM (Montrer TTN Anticorps)) of human p73
The findings of this study suggested that the polymorphism G4C14-to-A4T14 in p73 gene might be associated with severe spermatogenesis impairment and could affect the susceptibility to male infertility with severe spermatogenesis impairment in Chinese population.
Authors confirmed that miR (Montrer MLXIP Anticorps)-200a could directly bind to TP73-AS1 and the 3'UTR (Montrer UTS2R Anticorps) of HMGB1 (Montrer HMGB1 Anticorps); TP73-AS1 competed with HMGB1 (Montrer HMGB1 Anticorps) for miR (Montrer MLXIP Anticorps)-200a binding.
The p73 gene may play a role as a tumor suppressor in the colorectal cancer progression.
TP73 expression in cervical cancer was significantly higher than that in normal cervical squamous epithelium (meta-analysis)
Expression of XAF1 (Montrer XAF1 Anticorps) and TAp73 was also upregulated in casticin-treated T24 cells.
This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.
tumor protein p73
, tumor protein p73-like
, p53-like transcription factor
, p53-related protein
, transformation related protein 73