Aperçu des produits pour WWTR1 (WWTR1) Kits ELISA

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WW Domain Containing Transcription Regulator 1 Kits ELISA (WWTR1)
Chez www.anticorps-enligne.fr sont 3 WW Domain Containing Transcription Regulator 1 (WWTR1) Kits ELISA de 3 de différents fournisseurs disponibles. De plus, nous expédions WWTR1 Anticorps (53) et WWTR1 Protéines (5) et beaucoup plus de produits pour cette protéine. Un total de 65 WWTR1 produits sont actuellement listés.
Synonymes:
2310058J06Rik, 2610021I22Rik, C78399, Taz, WWTR1
list all ELISA KIts Gène GeneID UniProt
WWTR1 25937 Q9GZV5
Souris WWTR1 WWTR1 97064 Q9EPK5
Rat WWTR1 WWTR1 295062  

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WWTR1 (WWTR1) Kits ELISA par réactivité

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Plus Kits ELISA pour WWTR1 partenaires d'interaction

Zebrafish WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. Yap (Montrer YAP1 Kits ELISA)/Taz (Montrer TAZ Kits ELISA)-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt retinal pigment epithelium identity in zebrafish.

  2. Taz (Montrer TAZ Kits ELISA) is required in the anteroposterior patterning of the pronephric progenitor domain in the intermediate mesoderm, acting in part by regulating retinoic acid signaling in the pronephric progenitor field in the intermediate mesoderm.

  3. Taz (Montrer TAZ Kits ELISA)-depleted larvae displayed patterning defects in ventral cranial vessels that correlate with lateral displacement of thyroid follicles

  4. When transcriptional coactivators Yap (Montrer YAP1 Kits ELISA) and Taz (Montrer TAZ Kits ELISA) were restricted from interacting with Tead transcription factors through expression of a dominant negative transgene, cardiac precursors failed to migrate completely to the midline.

  5. TAZ (Montrer TAZ Kits ELISA) has a critical role in osteoblast differentiation in vivo

Human WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. ETAR (Montrer EDNRA Kits ELISA) stimulation acted via downstream G-protein Galphaq (Montrer GNAQ Kits ELISA)/11 and Rho GTPase (Montrer RACGAP1 Kits ELISA) to suppress the Hippo pathway, thus leading to YAP (Montrer YAP1 Kits ELISA)/TAZ (Montrer TAZ Kits ELISA) activation, which was required for ETAR (Montrer EDNRA Kits ELISA)-induced tumorigenesis. Overall, these results indicate a critical role of the YAP (Montrer YAP1 Kits ELISA)/TAZ (Montrer TAZ Kits ELISA) axis in ETAR (Montrer EDNRA Kits ELISA) signaling

  2. Various studies show that in human cancers, the Hippo pathway is frequently deregulated allowing YAP1 (Montrer YAP1 Kits ELISA) and TAZ (Montrer TAZ Kits ELISA) to escape the inhibition by the Hippo pathway. The upregulation of YAP1 (Montrer YAP1 Kits ELISA) and TAZ (Montrer TAZ Kits ELISA) induces epithelial-mesenchymal transition and increases drug resistance in cancer cells. TAZ (Montrer TAZ Kits ELISA) is implicated in cancer stemness.[review]

  3. Results demonstrate a pivotal role for TAZ (Montrer TAZ Kits ELISA) in regulating the differentiation of Treg cells and TH17 cells.

  4. the transcription regulators YAP (Montrer YAP1 Kits ELISA) and TAZ (Montrer TAZ Kits ELISA) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.

  5. In colorectal carcinoma TIAM1 suppresses tumor progression by regulating YAP (Montrer YAP1 Kits ELISA)/TAZ (Montrer TAZ Kits ELISA) activity.

  6. Growing evidence suggests that transcriptional effectors of the Hippo pathway, YAP (Montrer YAP1 Kits ELISA) and TAZ (Montrer TAZ Kits ELISA), promote resistance to various anti-cancer therapies, including cytotoxic chemotherapy, molecular targeted therapy, and radiation therapy. [review]

  7. SGK1 (Montrer SGK1 Kits ELISA) promotes YAP (Montrer YAP1 Kits ELISA)/TAZ (Montrer TAZ Kits ELISA) transcriptional activity. SGK1 (Montrer SGK1 Kits ELISA) enhances YAP (Montrer YAP1 Kits ELISA)/TAZ (Montrer TAZ Kits ELISA) activity by upregulating YAP (Montrer YAP1 Kits ELISA)/TAZ (Montrer TAZ Kits ELISA). SGK1 (Montrer SGK1 Kits ELISA) is a transcriptional target of YAP (Montrer YAP1 Kits ELISA). SGK1 (Montrer SGK1 Kits ELISA) stabilizes TAZ (Montrer TAZ Kits ELISA) by inhibiting GSK3beta (Montrer GSK3b Kits ELISA).

  8. YAP (Montrer YAP1 Kits ELISA) and TAZ (Montrer TAZ Kits ELISA), which are inhibited by the HIPPO tumor suppressor pathway, modify PI3K (Montrer PIK3CA Kits ELISA)/AKT (Montrer AKT1 Kits ELISA) pathway signaling in endometrial cancer.

  9. These results suggest that vinculin (Montrer VCL Kits ELISA) promotes the nuclear localization of transcription factor TAZ (Montrer TAZ Kits ELISA) to inhibit the adipocyte differentiation on rigid extracellular matrix.

  10. TAZ (Montrer TAZ Kits ELISA) regulates cell proliferation and sensitivity to vitamin D3 in intrahepatic cholangiocarcinoma by regulating tp53 (Montrer TP53 Kits ELISA)/CYP24A1 (Montrer CYP24A1 Kits ELISA) pathway.

Mouse (Murine) WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. Results demonstrate a pivotal role for TAZ (Montrer TAZ Kits ELISA) in regulating the differentiation of Treg cells and TH17 cells.

  2. ABL (Montrer ABL1 Kits ELISA) potentiated the assembly and activation of the RUNX2 (Montrer RUNX2 Kits ELISA)-TAZ (Montrer TAZ Kits ELISA) master transcription factor complex that is required for osteoblastogenesis, while antagonizing PPARgamma (Montrer PPARG Kits ELISA)-mediated adipogenesis.

  3. the transcription regulators YAP (Montrer YAP1 Kits ELISA) and TAZ (Montrer TAZ Kits ELISA) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.

  4. These results suggest that vinculin (Montrer VCL Kits ELISA) promotes the nuclear localization of transcription factor TAZ (Montrer TAZ Kits ELISA) to inhibit the adipocyte differentiation on rigid extracellular matrix.

  5. TAZ (Montrer TAZ Kits ELISA) represents a previously unrecognized factor that contributes to the critical process of steatosis-to-Nonalcoholic Steatohepatitis progression.

  6. both Snail (Montrer SNAI1 Kits ELISA) and Slug (Montrer SNAI2 Kits ELISA) are able to form binary complexes with either YAP (Montrer YAP1 Kits ELISA) or TAZ (Montrer TAZ Kits ELISA) that, together, control YAP (Montrer YAP1 Kits ELISA)/TAZ (Montrer TAZ Kits ELISA) transcriptional activity and function throughout mouse development.

  7. results demonstrate that skeletal stem/stromal cell mobilize Snail (Montrer SNAI1 Kits ELISA)/Slug (Montrer SNAI2 Kits ELISA)-YAP (Montrer YAP1 Kits ELISA)/TAZ (Montrer TAZ Kits ELISA) complexes to control stem cell function

  8. Results found that sclerostin (Montrer SOST Kits ELISA) enhances adipocyte differentiation in 3T3-L1 cells and reduced TAZ (Montrer TAZ Kits ELISA)-responsive transcriptional activity and TAZ (Montrer TAZ Kits ELISA)-responsive gene expression, indicating a role for TAZ (Montrer TAZ Kits ELISA) as a regulator of adipogenesis by sclerostin (Montrer SOST Kits ELISA).

  9. Expression of TAZ (Montrer TAZ Kits ELISA) promotes embryonic neural stem cell maintenance by enhancing stemness of neural stem cells during mammalian brain development.

  10. Tead2 transcription factors are crucial regulators of the cellular distribution of Yap (Montrer YAP1 Kits ELISA) and Taz (Montrer TAZ Kits ELISA), and together they control the expression of genes critical for EMT (Montrer ITK Kits ELISA) and metastasis.

WWTR1 profil antigène

Antigen Summary

This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with WWTR1

  • WW domain containing transcription regulator 1 (wwtr1) Elisa Kit
  • WW domain containing transcription regulator 1 (WWTR1) Elisa Kit
  • WW domain containing transcription regulator 1 (Wwtr1) Elisa Kit
  • 2310058J06Rik Elisa Kit
  • 2610021I22Rik Elisa Kit
  • C78399 Elisa Kit
  • Taz Elisa Kit
  • WWTR1 Elisa Kit

Protein level used designations for WWTR1

WW domain containing transcription regulator 1 , WW domain-containing transcription regulator protein 1 , taz , WW domain-containing transcription regulator protein 1-like , transcriptional co-activator with PDZ-binding motif , transcriptional coactivator with PDZ-binding motif , transcriptional coactivator with PDZ binding motif , transcriptional co-activator with PDZ-binding motif (TA)Z , transcriptional co-activator with PDZ-binding motif (TAZ)

GENE ID SPECIES
496155 Xenopus laevis
568008 Danio rerio
100050661 Equus caballus
100401831 Callithrix jacchus
100437619 Pongo abelii
100493170 Xenopus (Silurana) tropicalis
100522573 Sus scrofa
100592028 Nomascus leucogenys
25937 Homo sapiens
609743 Canis lupus familiaris
614786 Bos taurus
97064 Mus musculus
295062 Rattus norvegicus
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