You are viewing an incomplete version of our website. Please click to reload the website as full version.

Aperçu des produits pour anti-FMR1 (FMR1) Anticorps

Full name:
anti-Fragile X Mental Retardation 1 Anticorps (FMR1)
Chez sont 171 Fragile X Mental Retardation 1 (FMR1) Anticorps de 26 de différents fournisseurs disponibles. De plus, nous expédions FMR1 Protéines (7) et FMR1 Kits (5) et beaucoup plus de produits pour cette protéine. Un total de 190 FMR1 produits sont actuellement listés.
AT24755, BcDNA:GM08679, cg6203, dfmr, dfmr1, dFmrp, dfxr, dfxr1, dFXRP, Dmel\\CG6203, dmfr1, EP(3)3517, fmr, Fmr-1, fmr1, Fmrp, FRAXA, FXR, POF, POF1, zFMR1

Réactivités les plus populaires pour anti-FMR1 (FMR1) Anticorps

Sélectionnez vos espèces et l'application

anti-Human FMR1 Anticorps:

anti-Rat (Rattus) FMR1 Anticorps:

anti-Mouse (Murine) FMR1 Anticorps:

Tous anti-FMR1 Anticorps disponible

Vous arrivez à notre recherche pré-filtrée.

anti-FMR1 Anticorps mieux référencés

  1. Fruit Fly (Drosophila melanogaster) Monoclonal FMR1 Primary Antibody pour ICC, IF - ABIN108599 : Wan, Dockendorff, Jongens, Dreyfuss: Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein. dans Molecular and cellular biology 2000 (PubMed)
    Show all 7 references for ABIN108599

  2. Bat Polyclonal FMR1 Primary Antibody pour WB - ABIN610747 : Anderson, Teutsch, Dong, Wortis: An essential role for Bruton's [corrected] tyrosine kinase in the regulation of B-cell apoptosis. dans Proceedings of the National Academy of Sciences of the United States of America 1996 (PubMed)
    Show all 2 references for ABIN610747

  3. Human Polyclonal FMR1 Primary Antibody pour ELISA, IHC (p) - ABIN451678 : Hanson, Blank, Valenzuela, Garner, Madison: The functional nature of synaptic circuitry is altered in area CA3 of the hippocampus in a mouse model of Down's syndrome. dans The Journal of physiology 2007 (PubMed)

  4. Human Polyclonal FMR1 Primary Antibody pour EIA, WB - ABIN452426 : Dölen, Osterweil, Rao, Smith, Auerbach, Chattarji, Bear: Correction of fragile X syndrome in mice. dans Neuron 2007 (PubMed)

  5. Human Polyclonal FMR1 Primary Antibody pour EIA, WB - ABIN453027 : Yuhas, Walichiewicz, Pan, Zhang, Casillas, Hagerman, Tassone: High-risk fragile x screening in Guatemala: use of a new blood spot polymerase chain reaction technique. dans Genetic testing and molecular biomarkers 2009 (PubMed)

  6. Human Polyclonal FMR1 Primary Antibody pour ICC, IF - ABIN443330 : Zhang, Brown, Hyland, Chen, Kronengold, Fleming, Kohn, Moroz, Kaczmarek: Regulation of neuronal excitability by interaction of fragile X mental retardation protein with slack potassium channels. dans The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 (PubMed)

Plus d’anticorps contre FMR1 partenaires d’interaction

Fruit Fly (Drosophila melanogaster) Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. Fmr1 protein associates with ninaE (Montrer RHO Anticorps) mRNA and represses its translation.

  2. Our data strongly support a gain-of-function pathogenic mechanism of PQBP1 (Montrer PQBP1 Anticorps) c.459_462delAGAG and c.463_464dupAG mutations, and suggest that therapeutic strategies to restore FMRP function may be beneficial for those patients

  3. dFMRP cooperates with Piwi in maintaining genome integrity by silencing heterochromatic genes and suppressing transposon expression.

  4. results show Fragile X Mental Retardation Protein (FMRP) shapes neuron class-specific calcium signaling in excitatory vs. inhibitory neurons in developing learning/memory circuitry, and that FMRP mediates activity-dependent regulation of calcium signaling specifically during the early-use critical period.

  5. results support a model whereby dFMRP can modulate the neurotoxicity caused by TDP-43 (Montrer TARDBP Anticorps) overexpression

  6. demonstrate that Zfrp8 genetically interacts with Fmr1 and tral (Montrer LSM14A Anticorps) in an antagonistic manner. Zfrp8 and FMRP both control heterochromatin packaging, also in opposite ways

  7. dFmr1 protein is essential for proper cardiac function and establish the fly as a new model for studying the role(s) of FraX proteins in the heart.

  8. These results show that dfmr1 acts in a neuron type-specific activity-dependent manner for sculpting dendritic arbors during early-use, critical period development of learning and memory circuitry in the Drosophila brain.

  9. upon the stimulation of replication stress, dFMR1 is associated with chromatin in a domain-specific manner, which is essential for its ability to induce the phosphorylation of H2Av (Montrer H2AFV Anticorps).

  10. FMRP inhibits translation by binding directly to the L5 protein on the 80S ribosome.

Human Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. Study provides evidence linking white matter microstructure to executive dysfunction and elevated FMR1 mRNA and FMR1 exon 1/intron 1 boundary methylation in women with a FMR1 premutation expansion without fragile X-associated tremor/ataxia (Montrer USP14 Anticorps) syndrome

  2. a shared dataset of FMRP consensus binding sequences (FCBS), which were reproducibly identified in two published FMRP CLIP sequencing datasets.

  3. Individuals with the FMR1 permutation had a higher rate of autism spectrum symptoms in males and obsessive-compulsive symptoms in female permutation carriers.

  4. multistep FMR1 mutations involving the gain or loss of several CGGs seem to underlie the evolution of the repeat.

  5. The primary objective of this review is to familiarize reproductive health care providers including reproductive endocrinology and infertility specialists with the different phenotypes encompassing FMR1 premutation carriers

  6. Promoter methylation status of FMR1, mutations in its sequence and copy number variations in genes associated with intellectual disability were investigated. In 25 independent male patients without expansion, the promoter region was unmethylated; one patient with a full mutation showed methylation mosaicism; and a female patient had 81.2% of CpG sites methylated and 18.8% hemimethylated.

  7. Our data strongly support a gain-of-function pathogenic mechanism of PQBP1 (Montrer PQBP1 Anticorps) c.459_462delAGAG and c.463_464dupAG mutations, and suggest that therapeutic strategies to restore FMRP function may be beneficial for those patients

  8. Findings characterize the mental health of women with the FMR1 premutation to represent escalating risk for major depressive disorder and anxiety disorders over time

  9. data provide evidence that the CGG-repeat numbers below 26 or above 34 of FMR1 gene are also associated with disease risks

  10. unlike MutSbeta, MutSalpha may also act to protect against repeat contractions in the Fmr1 gene

Zebrafish Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. We identified thousands of clustered RNA editing sites in the zebrafish transcriptome and showed that Fmrp biochemically interacts with the Adar2a protein. The expression levels of the adar (Montrer ADAR Anticorps) genes and Adar2 (Montrer ADARB1 Anticorps) protein increased in fmr1-/- zebrafish

  2. Loss-of-function fmr1 mutants carrying an anti-fmr1 miRNA transgene show abnormal neuronal morphology and connectivity similar to that seen in human fragile X syndrome.

Mouse (Murine) Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. Male offspring of Fmr1+/- mothers, independent of their own Fmr1 genotype, exhibit social behavior abnormality.

  2. This study demonstrated that alterations in intrinsic properties in individual neurons are involved in the abnormal excitability of cortical circuitry in Fmr-1 knockout mice.

  3. One third of the putative mRNA targets described for FMRP appear to be transported in granules and FMRP is more abundant in granules than in polyribosomes. This observation supports a primary role for FMRP in granules biology.

  4. Study showed that Fmr1 knock-out astrocytes affect the dendritic arborization of all subtypes of hippocampal neurons and that select populations of hippocampal neurons are more effected by this astrocyte-mediated developmental delay; specifically, the stellate neurons grown on Fmr1 knock-out astrocytes exhibit the most pervasive developmental delays

  5. The data reveal an age-dependent deficit in long-term potentiation in Fmr1KO mice, which may correlate to some of the complex age-related deficits in Fragile X syndrome.

  6. increased white matter seen in the FMR1-KO-FVB could be highlighting a structural over-connectivity, which could lead to some of the behavioral abnormalities seen with the FMR1-KO-FVB mice

  7. Study shows deficits in habituation of neural responses to repeated sounds in the Fragile X Mental Retardation gene (Fmr1) KO mice as seen in humans with fragile X syndrome.

  8. we find abnormal patterns of coupling between theta and gamma oscillations in perisomatic and dendritic hippocampal CA1 (Montrer CA1 Anticorps) local field potentials of the Fmr1 knockout mice.

  9. This study demonstrated that in the active phase of the circadian cycle, Fmr1 KO mice are hyperactive, and demonstrate reduced anxiety and impaired learning and memory.

  10. Study reveals a mechanism for the local regulation of translation by miR (Montrer MLXIP Anticorps)-181d and FMRP during axon development.

FMR1 profil antigène

Antigen Summary

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Alternative names and synonyms associated with FMR1

  • CG6203 gene product from transcript CG6203-RC (Fmr1) anticorps
  • fragile X mental retardation 1 (FMR1) anticorps
  • fragile X mental retardation 1 (Fmr1) anticorps
  • fragile X mental retardation 1 (fmr1) anticorps
  • fragile X mental retardation syndrome 1 (Fmr1) anticorps
  • AT24755 anticorps
  • BcDNA:GM08679 anticorps
  • cg6203 anticorps
  • dfmr anticorps
  • dfmr1 anticorps
  • dFmrp anticorps
  • dfxr anticorps
  • dfxr1 anticorps
  • dFXRP anticorps
  • Dmel\\CG6203 anticorps
  • dmfr1 anticorps
  • EP(3)3517 anticorps
  • fmr anticorps
  • Fmr-1 anticorps
  • fmr1 anticorps
  • Fmrp anticorps
  • FRAXA anticorps
  • FXR anticorps
  • POF anticorps
  • POF1 anticorps
  • zFMR1 anticorps

Protein level used designations for FMR1

CG6203-PA , CG6203-PB , CG6203-PC , CG6203-PD , CG6203-PE , CG6203-PF , CG6203-PG , CG6203-PH , CG6203-PI , Fmr1-PA , Fmr1-PB , Fmr1-PC , Fmr1-PD , Fmr1-PE , Fmr1-PF , Fmr1-PG , Fmr1-PH , Fmr1-PI , Fragile-X mental retardation protein , Fragile-X-related , dFmr1 , drosophila fragile X mental retardation protein , fragile X , fragile X mental retardation , fragile X mental retardation 1 , fragile X mental retardation gene , fragile X mental retardation protein , fragile X protein , fragile X related protein , fragile X-related , fragile x related , fragile-X , fragile X mental retardation protein 1 , fragile X mental retardation protein 1 homolog , fragile X mental retardation syndrome 1 homolog , fragile X mental retardation-1 protein , protein FMR-1 , ragile X mental retardation protein , fragile X mental retardation 1 protein , FMRP , mFmr1p

37528 Drosophila melanogaster
465894 Pan troglodytes
2332 Homo sapiens
481070 Canis lupus familiaris
24948 Rattus norvegicus
259191 Danio rerio
422395 Gallus gallus
100155078 Sus scrofa
507482 Bos taurus
100172902 Pongo abelii
14265 Mus musculus
Fournisseurs de qualité sélectionnés pour anti-FMR1 (FMR1) Anticorps
Avez-vous cherché autre chose?