Aperçu des produits pour anti-MEGF10 (MEGF10) Anticorps

Full name:
anti-Multiple EGF-Like-Domains 10 Anticorps (MEGF10)
Chez www.anticorps-enligne.fr sont 16 Multiple EGF-Like-Domains 10 (MEGF10) Anticorps de 2 de différents fournisseurs disponibles. De plus, nous expédions MEGF10 Protéines (7) et beaucoup plus de produits pour cette protéine. Un total de 23 MEGF10 produits sont actuellement listés.
3000002B06Rik, EMARDD, Gm331
afficher tous les anticorps Gène GeneID UniProt
MEGF10 291445  
MEGF10 84466 Q96KG7
MEGF10 70417 Q6DIB5

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anti-Rat (Rattus) MEGF10 Anticorps:

anti-Human MEGF10 Anticorps:

anti-Mouse (Murine) MEGF10 Anticorps:

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Plus d’anticorps contre MEGF10 partenaires d’interaction

Human Multiple EGF-Like-Domains 10 (MEGF10) interaction partners

  1. MEGF10 mutations can cause myopathy with adult-onset respiratory insufficiency

  2. results indicate that myogenin (Montrer MYOG Anticorps) is a positive regulator in transcriptional regulation of MEGF10 in skeletal muscle

  3. Mutations in MEGF10 cause a recessive congenital myopathy with minicores and suggest satellite cell dysfunction as the pathogenic mechanism

  4. Mutations in MEGF10, a regulator of satellite cell myogenesis, cause early onset myopathy, areflexia, respiratory distress and dysphagia (EMARDD)

  5. The results of this study suggested that no association between schizophrenia and rs27388 of the MEGF10 gene in Chinese case-control sample.

  6. MEGF10 is involved in the uptake of amyloid-beta peptide (Abeta42) in the brain.

  7. in a system of forced expression by transfection, MEGF10 function can be modulated by the ATP binding cassette transporter ABCA1, ortholog to CED-7

  8. Human MEGF10 is an ortholog of Ced1 (Montrer IFT122 Anticorps).

  9. An interaction between MEGF10 and clathrin assembly protein complex 2 medium chain (AP50 (Montrer AP2M1 Anticorps)), a component of clathrin-coated pits was identified.

  10. In expression studies, MEGF10 had higher expression levels in the affected than the unaffected (p = .015). Schizophrenia patients with a 1/1 genotype at rs27388 had higher expressions than those patients with 1/2 and 2/2 genotypes (p = .0008).

Mouse (Murine) Multiple EGF-Like-Domains 10 (MEGF10) interaction partners

  1. Megf10 binds with high affinity to C1q, an eat-me signal for apoptotic cells. Cells expressing Megf10 with EMARDD mutations have impaired apoptotic cell clearance and impaired binding to C1q.

  2. studies reveal a novel role for astrocytes in mediating synapse elimination in the developing and adult brain, identify MEGF10 and MERTK (Montrer MERTK Anticorps) as critical proteins in the synapse remodelling underlying neural circuit refinement

  3. Cysteine mutations cause defective tyrosine phosphorylation in MEGF10 myopathy.

  4. These results indicated that both Jedi-1 (Montrer PEAR1 Anticorps) and MEGF10 can mediate phagocytosis independently through the recruitment of Syk (Montrer SYK Anticorps).

  5. in mouse, two related transmembrane proteins, MEGF10 and MEGF11 (Montrer MEGF11 Anticorps), have critical roles in the formation of mosaics by two retinal interneuron subtypes, starburst amacrine cells and horizontal cells

  6. Megf10 represents a novel transmembrane protein that impinges on Notch (Montrer NOTCH1 Anticorps) signaling to regulate the satellite cell population balance between proliferation and differentiation.

MEGF10 profil antigène

Antigen Summary

This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene.

Alternative names and synonyms associated with MEGF10

  • multiple EGF-like domains 10 (Megf10) anticorps
  • multiple EGF-like-domains 10 (MEGF10) anticorps
  • multiple EGF-like-domains 10 (Megf10) anticorps
  • 3000002B06Rik anticorps
  • EMARDD anticorps
  • Gm331 anticorps

Protein level used designations for MEGF10

multiple epidermal growth factor-like domains protein 10 , multiple EGF-like domains protein 10

291445 Rattus norvegicus
84466 Homo sapiens
70417 Mus musculus
427126 Gallus gallus
474665 Canis lupus familiaris
100515713 Sus scrofa
539136 Bos taurus
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