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anti-Aldehyde Dehydrogenase 1 Family, Member A2 Anticorps (ALDH1A2)
Chez www.anticorps-enligne.fr sont 77 Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2) Anticorps de 18 de différents fournisseurs disponibles. De plus, nous expédions Aldehyde Dehydrogenase 1 Family, Member A2 Protéines (8) et Aldehyde Dehydrogenase 1 Family, Member A2 Kits (4) et beaucoup plus de produits pour cette protéine. Un total de 94 Aldehyde Dehydrogenase 1 Family, Member A2 produits sont actuellement listés.
Synonymes:
Aldh1a7, AV116159, fb50h01, RALDH(II), Raldh-2, Raldh1, Raldh2, RALDH2-T

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anti-Aldehyde Dehydrogenase 1 Family, Member A2 Anticorps mieux référencés

  1. Human Polyclonal ALDH1A2 Primary Antibody pour IHC, IHC (p) - ABIN4279209 : Kostareli, Holzinger, Bogatyrova, Hielscher, Wichmann, Keck, Lahrmann, Grabe, Flechtenmacher, Schmidt, Seiwert, Dyckhoff, Dietz, Höfler, Pawlita, Benner, Bosch, Plinkert, Plass, Weichenhan, Hess: HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas. dans The Journal of clinical investigation 2013 (PubMed)
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Plus d’anticorps contre Aldehyde Dehydrogenase 1 Family, Member A2 partenaires d’interaction

Human Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2) interaction partners

  1. Data show that hRALDH2 is not inhibited by its oxidation product, all-trans-RA, suggesting the absence of a negative feedback regulatory loop. Expression of the Raldh2 gene is known to be regulated by RA itself, suggesting that the main regulation of the hRALDH2 activity level is transcriptional.

  2. Study shows no evidence that genetic variants alter prostate cancer incidence, but show that SNPs in the ALDH1A2 gene affect prostate cancer mortality.

  3. a critical role of ALDH1A2-RAR (Montrer RARA Anticorps) signaling in the pathogenesis of head and neck cancer.

  4. High expression of ALDH1A2 and ALDH1B1 (Montrer ALDH1B1 Anticorps) mRNA was found to be significantly correlated to worser survival in all NSCLC patients.

  5. the distribution of RALDH1 (Montrer ALDH1A1 Anticorps), RALDH2, and RALDH3 (Montrer ALDH1A3 Anticorps) in the postnatal eye was determined.

  6. ALDH1A2 is involved in the regulation of cancer stem cell properties in neuroblastoma (Montrer ARHGEF16 Anticorps).

  7. Genetic association replicative and exploratory studies identify SNPs in ADA (Montrer ADA Anticorps) and MTR (Montrer MTR Anticorps) highly associated with isolated Neural tube defects (NTD)and SNP in ARID1A (Montrer ARID1A Anticorps) and ALDH1A2 associated with NTDs in whites and African Americans respectively.

  8. At the transcript level, the cisplatin + DEAB-resistant cells showed upregulated mRNA expression levels for ALDH1A2, ALDH1A3 (Montrer ALDH1A3 Anticorps) isozymes and CD44 (Montrer CD44 Anticorps) indicating the involvement of these markers in conferring chemoresistance

  9. DNA methylation (Montrer HELLS Anticorps) at multiple CpG sites is associated with loss of control over alcohol drinking.

  10. Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.

Zebrafish Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2) interaction partners

  1. Zebrafish foxc1a plays a crucial role in early somitogenesis by restricting the expression of Raldh2 directly.

  2. The novel aldh1a2 reporter line is driven by the complete set of regulatory sequences required for zebrafish development, reports novel sources of RA synthesis, and identifies the source of RA that promotes vertebral ossification.

  3. aldh1a2 participate to a positive loop required for branchial arches development in zebrafish

  4. Aldh1a2 is the primary aldehyde dehydrogenase acting during pancreas development and maternal Aldh1a2 activity persists in aldh1a2(um22) and aldh1a2(i26) mutant embryos.

  5. Studies indicate that raldh2 expression is critical for the formation of wound epithelium and blastema.

Mouse (Murine) Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2) interaction partners

  1. ALDH2 (Montrer ALDH2 Anticorps) mutation displays an inverse correlation of coronary collateral vessel formation in patients.

  2. Data suggest that retinoic acid and GM-CSF (Montrer CSF2 Anticorps)-induced retinal dehydrogenase 2 (RALDH2) expression in dendritic cells requires cooperative binding of transcription factor Sp1 (Montrer SP1 Anticorps) via the RA receptor/retinoid X receptor (Montrer RXRB Anticorps) complex to the Aldh1a2 (Montrer ALDH1A1 Anticorps) promoter.

  3. all three proteins (RDH10 (Montrer RDH10 Anticorps), RALDH2, and CRABP2 (Montrer CRABP2 Anticorps)) appeared to be required for ATRA production induced by activation of PPARgamma (Montrer PPARG Anticorps)

  4. Defects in interdigital programmed cell death and digit separation in Hoxa13 (Montrer HOXA13 Anticorps) mutant mice may be caused in part by reduced levels of RA signaling stemming from a loss in the direct regulation of Aldh1a2 (Montrer ALDH1A1 Anticorps)

  5. Raldh1 (Montrer ALDH1A1 Anticorps) and Raldh3 (Montrer ALDH1A3 Anticorps) influence enteric nervous system structure and function and heterozygosity for Raldh2 causes ENS defects

  6. ALDH1A2 expression was highest in ALDH(very-br) cells, intermediate in ALDH(dim) cells, and lowest in ALDH(br) cells.

  7. Upregulation of retinal dehydrogenase 2 in alternatively activated macrophages during retinoid-dependent type-2 immunity to helminth infection in mice.

  8. rendered Fgfr2IIIb (Montrer FGFR2 Anticorps)(-/-) embryos haploinsufficient for the Raldh2 and examined these embryos for the incidence and severity of duodenal atresia

  9. Expression of ALDH1A2 (Montrer ALDH1A1 Anticorps), BEX2 (Montrer BEX2 Anticorps), EGR2 (Montrer EGR2 Anticorps), CCL3 (Montrer CCL3 Anticorps) and PLAU (Montrer PLAU Anticorps) are upregulated in Toxoplasma gondiisusceptible C57BL/6 mice.

  10. RA via RALDH2 has separable functions in the developing spinal cord to (i) maintain high levels of FGF and Notch (Montrer NOTCH1 Anticorps) signaling and (ii) drive stem cell differentiation, thus restricting both the numbers and the pluripotent character of neural stem cells

Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2) profil antigène

Antigen Summary

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2)

  • aldehyde dehydrogenase 1 family, member A2 (Aldh1a2) anticorps
  • aldehyde dehydrogenase 1 family, member A2 (ALDH1A2) anticorps
  • aldehyde dehydrogenase 1 family, member A2 (aldh1a2) anticorps
  • aldehyde dehydrogenase family 1, subfamily A2 (Aldh1a2) anticorps
  • Aldh1a7 anticorps
  • AV116159 anticorps
  • fb50h01 anticorps
  • RALDH(II) anticorps
  • Raldh-2 anticorps
  • Raldh1 anticorps
  • Raldh2 anticorps
  • RALDH2-T anticorps

Protein level used designations for ALDH1A2

RALDH 2 , RalDH(II) , aldehyde dehydrogenase 1A2 , aldehyde dehydrogenase family 1 member A2 , aldehyde dehydrogenase family 1, subfamily A2 , ralDH2 , retinal dehydrogenase 2 , retinal dehydrogenase, type II , retinaldehyde-specific dehydrogenase type 2 , neckless , nls , no-fin , nof , retinaldehyde dehydrogenase 2 , RALDH(II) , alcohol dehydrogenase family 1, subfamily A2 , alcohol dehydrogenase family 1, subfamily A7

GENE ID SPECIES
116676 Rattus norvegicus
8854 Homo sapiens
116713 Danio rerio
395844 Gallus gallus
478319 Canis lupus familiaris
535075 Bos taurus
19378 Mus musculus
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