Aperçu des produits pour anti-SRSF1 (SRSF1) Anticorps

Full name:
anti-serine/arginine-Rich Splicing Factor 1 Anticorps (SRSF1)
Chez www.anticorps-enligne.fr sont 66 serine/arginine-Rich Splicing Factor 1 (SRSF1) Anticorps de 17 de différents fournisseurs disponibles. De plus, nous expédions SRSF1 Protéines (14) et SRSF1 Kits (10) et beaucoup plus de produits pour cette protéine. Un total de 98 SRSF1 produits sont actuellement listés.
Synonymes:
1110054N12Rik, 5730507C05Rik, 6330415C05Rik, AI482334, Asf, Asf1, AW491331, CG9383, dASF/SF2, dAsf1, DKFZp469K2419, Dmel\\CG9383, l(3)76BDq, Sf2, SF2p33, Sfrs1, sfrs1b, SRp30a, wu:fb80g05, zgc:65898, zgc:76897, zgc:111894

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anti-Human SRSF1 Anticorps:

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anti-SRSF1 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal SRSF1 Primary Antibody pour IHC, WB - ABIN2779013 : Velazquez-Dones, Hagopian, Ma, Zhong, Zhou, Ghosh, Fu, Adams: Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty. dans The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for 2779013

  2. Human Polyclonal SRSF1 Primary Antibody pour ICC, IF - ABIN4353084 : Brown, Dobrikov, Gromeier et al.: Mitogen-activated protein kinase-interacting kinase regulates mTOR/AKT signaling and controls the serine/arginine-rich protein kinase-responsive type 1 internal ribosome entry site-mediated ... dans Journal of virology 2014 (PubMed)
    Show all 2 references for 4353084

  3. Human Polyclonal SRSF1 Primary Antibody pour IHC (p), WB - ABIN652256 : Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications. dans Molecular & cellular proteomics : MCP 2007 (PubMed)

Plus d’anticorps contre SRSF1 partenaires d’interaction

Fruit Fly (Drosophila melanogaster) serine/arginine-Rich Splicing Factor 1 (SRSF1) interaction partners

  1. DLP (Montrer DMD Anticorps) and ASF1 are part of a predeposition complex, which is recruited by XNP (Montrer ATRX Anticorps) and is necessary to prevent DNA exposure in the nucleus.

  2. ASF1 cellular levels are tightly controlled by distinct pathways and provide a molecular mechanism for post-translational regulation of dASF1 and hASF1a (Montrer ASF1A Anticorps) by TLK (Montrer TLK2 Anticorps) kinases.

  3. dASF1 has a direct role in modifying chromatin structure during DNA replication and this function of dASF1 is important for the processivity of the replication machinery.

  4. Asf1 is directed via interactions with sequence-specific complexes to mediate silencing of specific target genes.

  5. Histone chaperones ASF1 and NAP1 (Montrer NAP1L1 Anticorps) differentially modulate removal of active histone marks by LID-RPD3 (Montrer HDAC1 Anticorps) complexes during NOTCH (Montrer NOTCH1 Anticorps) silencing.

Human serine/arginine-Rich Splicing Factor 1 (SRSF1) interaction partners

  1. The authors found that RNA recognition motif 1 (RRM1 (Montrer RRM1 Anticorps)) in SRSF1 binds PP1 (Montrer PPA1 Anticorps) and represses its catalytic function through an allosteric mechanism.

  2. We present a joint atomistic molecular dynamics (MD) and experimental study of two RRM-containing proteins bound with their single-stranded target RNAs, namely the Fox-1 (Montrer A2BP1 Anticorps) and SRSF1 complexes.The simulations predict unanticipated specific participation of Arg142 at the protein-RNA interface of the SRFS1 complex, which is subsequently confirmed by NMR and ITC measurements

  3. Using NMR spectroscopy with two separately expressed domains of SRSF1, we showed that several residues in the RNA-binding motif 2 interact with the N-terminal region of the RS domain (RS1 (Montrer RS1 Anticorps)).

  4. Especially, in SRSF1 morphants, bone cartilage formation was reduced in the brain and Nkx-2.5 (Montrer NKX2-5 Anticorps) expression was dramatically reduced in the heart of SRSF1 morphants. In addition, a dramatic reduction in functional chordin (Montrer CHRD Anticorps) RNA in SRSF1 morphants was observed suggesting that chordin (Montrer CHRD Anticorps) is one of the targets of SRSF1. Thus, we concluded that SRSF1 is an essential factor for pattern formation including heart, cartilage and germ lay

  5. results strongly support SRSF1 as a prognostic biomarker in SCLC and provide a rationale for personalized therapy in SCLC

  6. NSrp70 (Montrer NSRP1 Anticorps) acts as a new molecular counterpart for alternative splicing of target RNA, counteracting SRSF1 and SRSF2 (Montrer SRSF2 Anticorps) splicing activity.

  7. we have identified for the first time a potential mechanism that involves the essential splicing factor (Montrer SLU7 Anticorps) ASF/SF2 through which morphine regulates splicing specificity of the MOR (Montrer OPRM1 Anticorps) encoding gene, OPRM1 (Montrer OPRM1 Anticorps).

  8. Global splicing analysis with RNA-seq revealed that exons carrying the hnRNP H (Montrer HNRNPH1 Anticorps)-binding GGGGG motif are predisposed to be skipped compared to those carrying the SRSF1-binding GGAGG motif in both human and mouse brains.

  9. We present experimental evidence that splicing factor (Montrer SLU7 Anticorps) SRSF1, SRSF2 (Montrer SRSF2 Anticorps), U2AF35 (Montrer U2AF1 Anticorps), U2AF65 (Montrer U2AF59 Anticorps) and KHSRP (Montrer KHSRP Anticorps) expression levels in gastrointestinal tract (colon, gastric and pancreatic) tumors differ compare to healthy tissues and in cell lines

  10. These findings have revealed a molecular interplay between cellular SRSF1 and viral T-antigen in controlling JC virus gene expression.

Mouse (Murine) serine/arginine-Rich Splicing Factor 1 (SRSF1) interaction partners

  1. The expression levels of three splicing factors, ESRP1 (Montrer ESRP1 Anticorps), PTB (Montrer PTBP1 Anticorps) and SF2/ASF, are significantly altered during cardiac hypertrophy in mice.

  2. RRP1B suppresses metastatic progression by altering the transcriptome through its interaction with splicing regulators such as SRSF1

  3. Deletion of RRM1 (Montrer RRM1 Anticorps) eliminated the splicing activity of SRSF1 and thus cellular transformation.

  4. Specific effects on regulated splicing by SR proteins SRSF1 and SRSF2 (Montrer SRSF2 Anticorps) depends on a complex set of relationships with multiple other SR proteins in mammalian genomes.

  5. Treatment with IL-17 (Montrer IL17A Anticorps) prolongs the half-life of chemokine (Montrer CCL1 Anticorps) CXCL1 (Montrer CXCL1 Anticorps) mRNA via the adaptor TRAF5 (Montrer TRAF5 Anticorps) and the splicing-regulatory factor SF2 (ASF).

  6. analysis of the miRNA-mediated interaction between leukemia/lymphoma-related factor (LRF (Montrer ZBTB7A Anticorps)) and alternative splicing factor/splicing factor (Montrer SLU7 Anticorps) 2 (ASF/SF2) affects cell senescence and apoptosis

  7. Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 (Montrer SMN1 Anticorps) causes spinal muscular atrophy in the absence of SMN1 (Montrer SMN1 Anticorps)

  8. Both hnRNP A1 (Montrer HNRNPA1 Anticorps) and alternative splicing factor/splicing factor (Montrer SLU7 Anticorps) 2 contents rose in adenomas and during injury-induced hyperplasia compared to control lungs

  9. These results highlight the requirement of Sfrs1-mediated alternative splicing for the survival of retinal neurons, with sensitivity defined by the window of time in which the neuron was generated.

SRSF1 profil antigène

Antigen Summary

This gene encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 13.

Alternative names and synonyms associated with SRSF1

  • anti-silencing factor 1 (asf1) anticorps
  • serine/arginine-rich splicing factor 1 (srsf1) anticorps
  • serine/arginine-rich splicing factor 1 (SRSF1) anticorps
  • serine/arginine-rich splicing factor 1 (Srsf1) anticorps
  • serine/arginine-rich splicing factor 1b (srsf1b) anticorps
  • 1110054N12Rik anticorps
  • 5730507C05Rik anticorps
  • 6330415C05Rik anticorps
  • AI482334 anticorps
  • Asf anticorps
  • Asf1 anticorps
  • AW491331 anticorps
  • CG9383 anticorps
  • dASF/SF2 anticorps
  • dAsf1 anticorps
  • DKFZp469K2419 anticorps
  • Dmel\\CG9383 anticorps
  • l(3)76BDq anticorps
  • Sf2 anticorps
  • SF2p33 anticorps
  • Sfrs1 anticorps
  • sfrs1b anticorps
  • SRp30a anticorps
  • wu:fb80g05 anticorps
  • zgc:65898 anticorps
  • zgc:76897 anticorps
  • zgc:111894 anticorps

Protein level used designations for SRSF1

CG9383-PA , CG9383-PB , anti- silencing function 1 , anti-silencing factor , asf1-PA , asf1-PB , splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor) , ASF-1 , SR splicing factor 1 , alternative-splicing factor 1 , pre-mRNA-splicing factor SF2, P33 subunit , splicing factor 2 , splicing factor, arginine/serine-rich 1 , splicing factor arginine/serine-rich 1 , splicing factor, arginine/serine-rich 1B , ASF/SF2 , pre-mRNA-splicing factor SRp30a , splicing factor, arginine/serine-rich 1 (ASF/SF2) , serine/arginine-rich splicing factor 1B , splicing factor, arginine/serine-rich 1b

GENE ID SPECIES
40141 Drosophila melanogaster
399226 Xenopus laevis
772264 Gallus gallus
6426 Homo sapiens
609693 Canis lupus familiaris
654327 Sus scrofa
615796 Bos taurus
110809 Mus musculus
689890 Rattus norvegicus
100173318 Pongo abelii
393565 Danio rerio
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