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LINC01133 inhibits epithelial mesenchymal transformation and metastasis in colorectal neoplasms by directly binding to SRSF6 as a target mimic.
The authors propose that splicing at 3'ss A3 is dependent on binding of the enhancing SR proteins SRSF2 (Montrer SRSF2 Kits ELISA) and SRSF6 to the HIV-1 tat (Montrer TAT Kits ELISA) ESE and ESE2 (Montrer ELF5 Kits ELISA) sequence.
SRSF6 is a regulator of wound healing and tissue homeostasis in skin.
Zinc inhibits the activity of SRSF6 and promotes elimination of exon 4, leading to preferential generation of BimS.
The splicing factor (Montrer SLU7 Kits ELISA) SRSF6 is an oncoprotein that regulates the proliferation and survival of lung and colon cancer cells.
Phosphorylation of SRp55 by Dyrk1A (Montrer DYRK1A Kits ELISA) suppressed its ability to promote Tau exon 10 inclusion.
Report upregulation of Bim (Montrer BCL2L11 Kits ELISA) and the splicing factor SRp55 in melanoma cells from patients treated with selective BRAF (Montrer BRAF Kits ELISA) inhibitors.
SRp55 aids in the generation of partially spliced and unspliced HIV-1 mRNAs.
Serine- and arginine-rich proteins 55 and 75 (SRp55 and SRp75 (Montrer SRSF4 Kits ELISA)) induce production of HIV-1 vpr mRNA by inhibiting the 5'-splice site of exon 3.
Here, the authors report that specific SR proteins, particularly SRp40 (Montrer SRSF5 Kits ELISA) and SRp55, promote human immunodeficiency virus type 1 (HIV-1) Gag translation from unspliced (intron-containing) viral RNA.
Nova1 (Montrer NOVA1 Kits ELISA) isoforms exhibited differential effects on repressing the development of BAs. Moreover, overexpression of Nova1 (Montrer NOVA1 Kits ELISA) proteins reduced the serine/arginine splicing factor (Montrer SLU7 Kits ELISA) 6 (SRSF6) level by enhancing the generation of intron 2-included (SRSF6(+intron 2)) transcripts
The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.
splicing factor, arginine/serine-rich 6
, SR splicing factor 6
, pre-mRNA-splicing factor SRP55
, splicing factor, arginine/serine-rich, 55 kDa
, arginine/serine-rich splicing factor 6
, splicing factor, arginine/serine-rich 6b