Aperçu des produits pour Hexosaminidase A (HEXA) Kits ELISA

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Hexosaminidase A Kits ELISA (HEXA)
Chez www.anticorps-enligne.fr sont 22 Hexosaminidase A (HEXA) Kits ELISA de 9 de différents fournisseurs disponibles. De plus, nous expédions Hexosaminidase A Anticorps (136) et Hexosaminidase A Protéines (12) et beaucoup plus de produits pour cette protéine. Un total de 178 Hexosaminidase A produits sont actuellement listés.
DKFZp459O0432, fc04h11, Hex-1, HEXA, si:dkey-35i22.2, TSD, wu:fc04h11, wu:fv09f06

Hexosaminidase A (HEXA) Kits ELISA par réactivité

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Plus Kits ELISA pour Hexosaminidase A partenaires d'interaction

Mouse (Murine) Hexosaminidase A (HEXA) interaction partners

  1. Neu4 (Montrer NEU4 Kits ELISA) is not the only sialidase contributing to the metabolic bypass in Hexa(-/-) mice.

Human Hexosaminidase A (HEXA) interaction partners

  1. The alpha mutants E482K and G269S are defective in enzymatic activity, unprocessed by lysosomal proteases, and exhibit altered folding pathways compared with wild-type alpha. E482K is more severely misfolded than G269S, as observed by its aggregation and inability to associate with the HexA beta chain. Importantly, both mutants are retrotranslocated from the endoplasmic reticulum to the cytosol and are degraded by the ...

  2. reports a new missense mutation in the HEXA gene in two German siblings with late-onset Tay-Sachs disease and prominent psychiatric symptoms

  3. The silencing of the HEXA gene had a stronger immune inhibitory effect, thereby indicating a major involvement of beta-N-acetyl-hexosaminidase A isoenzyme within this mechanism.

  4. Human prostate cancer cells are characterised by a significant decrease in HexA activity.

  5. DNA reveals novel mutations in Iranian subjects causing Tay-Sachs disease in the alpha and beta subunits of HexA.

  6. GM2 (Montrer CYB5D2 Kits ELISA) gangliosidosis is caused by the gene mutation. (review)

  7. identified 27 different mutations, 14 of which were novel, in the HEXA gene and 14 different mutations, 8 of which unreported until now, in the HEXB (Montrer HEXB Kits ELISA) gene, and attempted to correlate these mutations with the clinical presentation of the patients

  8. HEXA gene in Argentinean patients affected with Tay-Sachs disease, overall 14 different mutations were identified, 8 of them were novel and lead to premature stop codons, drastic residues changes or a splicing defect.

  9. Beta-hexosaminidase over-expression affects lysosomal glycohydrolases expression and glycosphingolipid metabolism in mammalian cells.

  10. We report the first Jordanian Arab Tay-Sachs disease patient diagnosed by deficient beta-hexosaminidase A activity, mutation analysis revealed homozygosity for a nonsense HEXA mutation, c.78G>A (p.W26X)

Cow (Bovine) Hexosaminidase A (HEXA) interaction partners

  1. SNPs in the HEXA region on chromosome 10 have a protective effect against Bovine spongiform encephalopathy.

Hexosaminidase A (HEXA) profil antigène

Antigen Summary

This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

Alternative names and synonyms associated with Hexosaminidase A (HEXA)

  • hexosaminidase A (alpha polypeptide) (HEXA) Elisa Kit
  • hexosaminidase A (alpha polypeptide) (hexa) Elisa Kit
  • hexosaminidase A (LOC100228061) Elisa Kit
  • hexosaminidase A (Hexa) Elisa Kit
  • DKFZp459O0432 Elisa Kit
  • fc04h11 Elisa Kit
  • Hex-1 Elisa Kit
  • HEXA Elisa Kit
  • si:dkey-35i22.2 Elisa Kit
  • TSD Elisa Kit
  • wu:fc04h11 Elisa Kit
  • wu:fv09f06 Elisa Kit

Protein level used designations for Hexosaminidase A (HEXA) Kits ELISA

beta-hexosaminidase subunit alpha , beta-hexosaminidase subunit beta , beta-hexosaminidase alpha chain , hexosaminidase A (alpha polypeptide) , beta-hexosaminidase alpha-subunit , hexosaminidase A , Beta-hexosaminidase alpha chain , N-acetyl-beta-glucosaminidase subunit alpha , beta-N-acetylhexosaminidase subunit alpha , hexosaminidase subunit A , Hexose aminidase A (alpha polypeptide) , hexosaminidase A alpha

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15211 Mus musculus
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3073 Homo sapiens
504468 Bos taurus
487633 Canis lupus familiaris
100142664 Sus scrofa
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