Aperçu des produits pour anti-EPAS1 (EPAS1) Anticorps

Full name:
anti-Endothelial PAS Domain Protein 1 Anticorps (EPAS1)
Chez www.anticorps-enligne.fr sont 219 Endothelial PAS Domain Protein 1 (EPAS1) Anticorps de 21 de différents fournisseurs disponibles. De plus, nous expédions EPAS1 Kits (21) et EPAS1 Protéines (10) et beaucoup plus de produits pour cette protéine. Un total de 257 EPAS1 produits sont actuellement listés.
Synonymes:
bhlhe73, ecyt4, EPAS, EPAS-1, EPAS1, HIF-2alpha, hif2, hif2a, hif2alpha, hlf, HRF, mop2, pasd2

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anti-EPAS1 Anticorps mieux référencés

  1. Fish Polyclonal EPAS1 Primary Antibody pour ChIP, ELISA - ABIN151051 : Conrad, Freeman, Beitner-Johnson, Millhorn: EPAS1 trans-activation during hypoxia requires p42/p44 MAPK. dans The Journal of biological chemistry 1999 (PubMed)
    Show all 478 references for 151051

  2. Hamster Monoclonal EPAS1 Primary Antibody pour ChIP, ELISA - ABIN151063 : Bernhardt, Wiesener, Weidemann, Schmitt, Weichert, Lechler, Campean, Ong, Willam, Gretz, Eckardt: Involvement of hypoxia-inducible transcription factors in polycystic kidney disease. dans The American journal of pathology 2007 (PubMed)
    Show all 146 references for 151063

  3. Hamster Monoclonal EPAS1 Primary Antibody pour ELISA, IHC - ABIN250056 : Harvey, Kind, Pantaleon, Armstrong, Thompson: Oxygen-regulated gene expression in bovine blastocysts. dans Biology of reproduction 2004 (PubMed)
    Show all 19 references for 250056

  4. Hamster Monoclonal EPAS1 Primary Antibody pour ELISA, ICC - ABIN250055 : Mekhail, Gunaratnam, Bonicalzi, Lee: HIF activation by pH-dependent nucleolar sequestration of VHL. dans Nature cell biology 2004 (PubMed)
    Show all 15 references for 250055

  5. Human Monoclonal EPAS1 Primary Antibody pour AA, ELISA - ABIN863099 : Kim, Perera, Zhou, Carretero, Yeh, Heathcote, Jackson, Nikolinakos, Ospina, Naumov, Brandstetter, Weigman, Zaghlul, Hayes, Padera, Heymach, Kung, Sharpless, Kaelin, Wong: HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice. dans The Journal of clinical investigation 2009 (PubMed)
    Show all 4 references for 863099

  6. Human Polyclonal EPAS1 Primary Antibody pour EIA, FACS - ABIN952733 : Yi, Liang, Huerta-Sanchez, Jin, Cuo, Pool, Xu, Jiang, Vinckenbosch, Korneliussen, Zheng, Liu, He, Li, Luo, Nie, Wu, Zhao, Cao, Zou, Shan, Li, Yang, Asan, Ni, Tian, Xu, Liu, Jiang, Wu, Zhou, Tang, Qin, Wang, Feng, Li, Huasang, Luosang, Wang, Chen, Wang, Zh: Sequencing of 50 human exomes reveals adaptation to high altitude. dans Science (New York, N.Y.) 2010 (PubMed)
    Show all 2 references for 952733

  7. Human Polyclonal EPAS1 Primary Antibody pour FACS, WB - ABIN654664 : Bougatef, Menashi, Khayati, Naïmi, Porcher, Podgorniak, Millot, Janin, Calvo, Lebbé, Mourah: EMMPRIN promotes melanoma cells malignant properties through a HIF-2alpha mediated up-regulation of VEGF-receptor-2. dans PLoS ONE 2010 (PubMed)
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  8. Human Polyclonal EPAS1 Primary Antibody pour WB - ABIN658111 : Mowat, Luhmann, Smith, Lange, Duran, Harten, Shukla, Maxwell, Ali, Bainbridge: HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia. dans PLoS ONE 2010 (PubMed)
    Show all 2 references for 658111

  9. Human Polyclonal EPAS1 Primary Antibody pour IF (p), IHC (p) - ABIN686662 : Li, Chen, Shao, Tang, Chen, Chen, Xu: Oxidative stress induces the decline of brain EPO expression in aging rats. dans Experimental gerontology 2016 (PubMed)

  10. Cow (Bovine) Polyclonal EPAS1 Primary Antibody pour WB - ABIN2779523 : Koizume, Yokota, Miyagi, Hirahara, Tsuchiya, Miyagi: Heterogeneity in binding and gene-expression regulation by HIF-2alpha. dans Biochemical and biophysical research communications 2008 (PubMed)

Plus d’anticorps contre EPAS1 partenaires d’interaction

Human Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. Findings show that hypoxia inducible factor 1 alpha subunit (HIF-1alpha (Montrer HIF1A Anticorps)) is phylogenetically conserved among most metazoans, whereas HIF-2alpha protein appeared later.

  2. proteomic experiments on Normoxic Neuroblastoma (Montrer ARHGEF16 Anticorps) cells to investigate HIF-2alpha downstream-regulated proteins or pathways

  3. HIF1A (Montrer HIF1A Anticorps) and HIF2A contribute to cancer stem cells survival but play different roles -HIF1A (Montrer HIF1A Anticorps) being more responsible for survival functions and HIF2A for self-renewal [review].

  4. The negative feedback modulation between LncRNA-SARCC/AR complex and HIF-2alpha signaling may then lead to differentially modulated RCC (Montrer XRCC1 Anticorps) progression in a VHL (Montrer VHL Anticorps)-dependent manner. Together, these results may provide us a new therapeutic approach via targeting this newly identified signal from LncRNA-SARCC to AR-mediated HIF-2alpha/C-MYC (Montrer MYC Anticorps) signals against RCC (Montrer XRCC1 Anticorps) progression.

  5. Results suggested that the oncogenic transcription factor HIF-2alpha stabilized VHL (Montrer VHL Anticorps) disease suppressor B-Myb (Montrer MYBL2 Anticorps), which is also a transcription factor, by physical interaction. Some B-Myb (Montrer MYBL2 Anticorps)-dependent gene expression was similarly affected by B-Myb (Montrer MYBL2 Anticorps) or HIF-2alpha knockdown, suggesting that stabilization of B-Myb (Montrer MYBL2 Anticorps) by HIF-2alpha may play a role in specific gene expressions.

  6. Data suggest a common mechanism by which DNA methyltransferase1 (DNMT1 (Montrer DNMT1 Anticorps)) and hypoxia inducible factors HIF1alpha (Montrer HIF1A Anticorps)/HIF2alpha regulate Sprouty2 (Spry2 (Montrer SPRY2 Anticorps)) transcription.

  7. Hypoxia microenvironment in hepatocellular carcinoma up-regulates HIF2/SCF (Montrer KITLG Anticorps) expression, which in turn promotes angiogenesis and HCC (Montrer FAM126A Anticorps) metastasis.

  8. CK1delta enhances EPO (Montrer EPO Anticorps) secretion from liver cancer cells under hypoxia by modifying HIF-2alpha and promoting its nuclear accumulation.

  9. LOX (Montrer LOX Anticorps), a hypoxia-responsive gene that encodes lysyl oxidase (Montrer LOX Anticorps), is activated by HIF-2-alpha more than HIF-1 (Montrer HIF1A Anticorps). Two new hypoxia response elements identified in the LOX (Montrer LOX Anticorps) promoter mediate most HIF responsiveness.

  10. Our results indicate that HPV16 E6/E7 indirectly upregulated the expression of VEGF by inhibition of liver kinase B1 expression and upregulation of hypoxia-inducible factor 2alpha expression,thus propose a human papillomavirus-liver kinase B1-hypoxia-inducible factor 2A-vascular endothelial growth factor axis for the tumorigenesis of lung cancer

Mouse (Murine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. this study shows that HIF-2alpha acts in resting macrophages as a phagocytosis suppressor implying an important relationship between the levels of HIF-2alpha and susceptibility to infection

  2. in neurons HIF-1 (Montrer HIF1A Anticorps) and HIF-2 have redundant functions for cellular survival under ischemic conditions. By contrast, lack of anti-survival factors in Hif1a (Montrer HIF1A Anticorps)/Hif2a-deficient mice might protect from early acute neuronal cell death and neurological impairment, indicating a benefit of HIF-pathway inhibition in neurons in the very acute phase after ischemic stroke

  3. HIF-2alpha is a novel regulator of neutrophil recruitment to colon tumors.

  4. AQP1 (Montrer AQP1 Anticorps) deficiency delays long-term ischemia-reperfusion resolution, partly through repressing angiogenesis mediated by destabilizing HIF-2alpha.

  5. HIF1alpha (Montrer HIF1A Anticorps) and HIF2alpha are dispensable for muscle stem cell function under normoxia but are required for maintaining satellite cell self-renewal in hypoxic environments.

  6. eIF3e (Montrer EIF3E Anticorps) is an angiogenesis suppressor. Silencing of eIF3e (Montrer EIF3E Anticorps) promotes blood perfusion recovery after limb ischemia through stabilization of hypoxia-inducible factor 2alpha activity.

  7. The regulatory connection between HIF-2alpha and VEGFR-1 (Montrer FLT1 Anticorps), VEGFR-2 (Montrer KDR Anticorps) and MMP2 (Montrer MMP2 Anticorps).

  8. HIF2alpha is essential for the acute postprandial regulation of hepatic glucagon (Montrer GCG Anticorps) signaling.

  9. demonstrate that HIF-2alpha is clearly implicated in the TSP1 (Montrer GZMA Anticorps) pulmonary regulation and provide new insights on its contribution to pulmonary arterial hypertension-driven vascular remodelling and vasoconstriction

  10. Findings identify a reciprocal activation mechanism involving HIF-2alpha and the zinc-ZIP8 (Montrer SLC39A8 Anticorps)-MTF1 (Montrer MTF1 Anticorps) axis during osteoarthritis pathogenesis that amplifies catabolic signaling and cartilage destruction.

Pig (Porcine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. immunostaining for HIF-1alpha (Montrer HIF1A Anticorps) and HIF-2alpha was observed during endochondral ossification; only HIF-2alpha was present at sites of intramembranous ossification

Cow (Bovine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. There was an association of an EPAS1 (HIF2alpha) double variant in the oxygen degradation domain of EPAS1 in Angus cattle with high altitude pulmonary hypertension (HAPH). There was upregulation of 26 of 27 HIF2alpha target genes in EPAS1 carriers with HAPH.

EPAS1 profil antigène

Antigen Summary

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.

Alternative names and synonyms associated with EPAS1

  • endothelial PAS domain protein 1 (EPAS1) anticorps
  • endothelial PAS domain protein 1 (epas1) anticorps
  • endothelial PAS domain protein 1 (Epas1) anticorps
  • bhlhe73 anticorps
  • ecyt4 anticorps
  • EPAS anticorps
  • EPAS-1 anticorps
  • EPAS1 anticorps
  • HIF-2alpha anticorps
  • hif2 anticorps
  • hif2a anticorps
  • hif2alpha anticorps
  • hlf anticorps
  • HRF anticorps
  • mop2 anticorps
  • pasd2 anticorps

Protein level used designations for EPAS1

endothelial PAS domain protein 1 , endothelial PAS domain-containing protein 1-like , EPAS-1 , HIF-1-alpha-like factor , HIF-1alpha-like factor , HIF-2-alpha , HIF2-alpha , PAS domain-containing protein 2 , basic-helix-loop-helix-PAS protein MOP2 , class E basic helix-loop-helix protein 73 , endothelial PAS domain-containing protein 1 , hypoxia-inducible factor 2 alpha , hypoxia-inducible factor 2-alpha , member of PAS protein 2 , HIF-related factor , HIF1 alpha-like factor , HIF1alpha-like factor , HLF (HIF1alpha-like factor) , Hif like protein , hypoxia inducible transcription factor 2alpha , mHLF , HIF-2 alpha , HIF2 alpha , hypoxia inducible factor 2, alpha subunit , hypoxia inducible factor 2a , HIF-2alpha

GENE ID SPECIES
459204 Pan troglodytes
714641 Macaca mulatta
100220014 Taeniopygia guttata
100396711 Callithrix jacchus
100439667 Pongo abelii
100543912 Meleagris gallopavo
100551891 Anolis carolinensis
100606638 Nomascus leucogenys
2034 Homo sapiens
13819 Mus musculus
29452 Rattus norvegicus
444145 Xenopus laevis
395596 Gallus gallus
474578 Canis lupus familiaris
100037272 Sus scrofa
282711 Bos taurus
100068622 Equus caballus
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