Aperçu des produits pour anti-BCL2 (BCL2) Anticorps

Full name:
anti-B-Cell CLL/lymphoma 2 Anticorps (BCL2)
Chez www.anticorps-enligne.fr sont 1098 B-Cell CLL/lymphoma 2 (BCL2) Anticorps de 40 de différents fournisseurs disponibles. De plus, nous expédions BCL2 Kits (91) et BCL2 Protéines (28) et beaucoup plus de produits pour cette protéine. Un total de 1250 BCL2 produits sont actuellement listés.
Synonymes:
AW986256, BCL-2, Bcl2, C430015F12Rik, D630044D05Rik, D830018M01Rik, PPP1R50

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anti-BCL2 Anticorps mieux référencés

  1. Human Polyclonal BCL2 Primary Antibody pour IF, IHC (p) - ABIN388095 : Zheng, Zhou, Ye, Li, Bai, Zhang: The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells. dans World journal of surgical oncology 2010 (PubMed)
    Show all 19 references for 388095

  2. Human Polyclonal BCL2 Primary Antibody pour IF (p), IHC (p) - ABIN707156 : Wang, Ma, Su: NF-?B pathway contributes to cadmium-induced apoptosis of porcine granulosa cells. dans Biological trace element research 2013 (PubMed)
    Show all 6 references for 707156

  3. Human Monoclonal BCL2 Primary Antibody pour FACS, IHC (fro) - ABIN118990 : Hockenbery, Nuñez, Milliman, Schreiber, Korsmeyer: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. dans Nature 1991 (PubMed)
    Show all 4 references for 118990

  4. Human Monoclonal BCL2 Primary Antibody pour FACS, WB - ABIN1105506 : Gallatin, Weissman, Butcher: A cell-surface molecule involved in organ-specific homing of lymphocytes. 1983. dans Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 2 references for 1105506

  5. Human Monoclonal BCL2 Primary Antibody pour IHC (fro), IF - ABIN1105504 : Ngan, Chen-Levy, Weiss, Warnke, Cleary: Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation. dans The New England journal of medicine 1988 (PubMed)
    Show all 2 references for 1105504

  6. Human Monoclonal BCL2 Primary Antibody pour FACS - ABIN1105508 : Tanaka, Yoshimi, Maeyama, Hagimoto, Kuwano, Hara: Resistance to Fas-mediated apoptosis in human lung fibroblast. dans The European respiratory journal 2002 (PubMed)
    Show all 2 references for 1105508

  7. Mouse (Murine) Polyclonal BCL2 Primary Antibody pour IF (cc), IF (p) - ABIN683428 : Yan, Yuan, Gao, Huang, Ma, Gao, Zhang, Guo, Chen: Overexpression of Human E46K Mutant ?-Synuclein Impairs Macroautophagy via Inactivation of JNK1-Bcl-2 Pathway. dans Molecular neurobiology 2014 (PubMed)

  8. Human Polyclonal BCL2 Primary Antibody pour WB - ABIN657744 : Feng, Stachura, White, Gutierrez, Zhang, Sanda, Jette, Testa, Neuberg, Langenau, Kutok, Zon, Traver, Fleming, Kanki, Look: T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. dans Cancer cell 2010 (PubMed)

  9. Human Polyclonal BCL2 Primary Antibody pour IHC, WB - ABIN2792106 : Chen, Valencia, Zhong, McColl, Roderick, Bootman, Berridge, Conway, Holmes, Mignery, Velez, Distelhorst: Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate. dans The Journal of cell biology 2004 (PubMed)

  10. Human Polyclonal BCL2 Primary Antibody pour EIA, IHC (p) - ABIN356812 : Liu, Zhou, Li, Sun, Lin, Lang, He, Cao, Yan, Wang, Lu, Han, Cao, Zhang, Zeng: Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. dans Cancer research 2008 (PubMed)

Plus d’anticorps contre BCL2 partenaires d’interaction

Mouse (Murine) B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. This study provides evidence from transgenic mouse models that Crebbp (Montrer CREBBP Anticorps) deletion results in deficits in B-cell development and can cooperate with Bcl2 overexpression to promote B-cell lymphoma.

  2. an essential role for the binding of BCL2 to BIM (Montrer BCL2L11 Anticorps) in the survival of noncycling NK cells.

  3. LIGHT signalling pathway combined with IFN-gamma (Montrer IFNG Anticorps) induces beta cells apoptosis via an NF-kappaB (Montrer NFKB1 Anticorps)/Bcl2-dependent mitochondrial pathway.

  4. Bcl-2 was highly expressed in tubulointerstitial infiltrates in (NZB x NZW)F1 (NZB/NZW) lupus-prone mice.

  5. The abnormal expression of epidermal cytokeratins suggests that Ha-Ras and Bcl-2 suppress the terminal differentiation and sustain the stem cell-like features in epidermal keratinocytes

  6. the augmentation of endogenous MTA1 (Montrer MTA1 Anticorps) expression during neuronal ischemic injury acts additionally to an endocrinous cascade orchestrating intimate interactions between ERalpha (Montrer ESR1 Anticorps) and BCL2 pathways.

  7. Interestingly, SKPs showed higher protein levels of Bcl-2, Nrf2 (Montrer NFE2L2 Anticorps), and HO-1 (Montrer HMOX1 Anticorps) than FBs (Montrer FBS Anticorps). SKPs exert a beneficial effect on resisting UVB-induced apoptosis, which may be associated with Bcl-2 and Nrf2 (Montrer NFE2L2 Anticorps) upregulation.

  8. Bcl-2 is an essential regulator in the survival of doublecortin (Montrer DCX Anticorps)-expressing immature neurons.

  9. Results show that the deletion of BCL-2, on its own or in concert with MCL-1 (Montrer MCL1 Anticorps), does not affect platelet production or platelet lifespan.

  10. the expression changes observed within the BCL2 family did not depend on STAT3 (Montrer STAT3 Anticorps) signalling, in line with its initiating role early in the process, but rather appear to result from relief of repression by STAT5 (Montrer STAT5A Anticorps).

Guinea Pig B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. bcl-2 and bax (Montrer BAX Anticorps) were expressed strongly in denervated guinea-pig facial muscle. [bcl-2; bax (Montrer BAX Anticorps)]

Human B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. MYC (Montrer MYC Anticorps) and BCL2 genetic alterations were profiled using next-generation sequencing and high-resolution single nucleotide polymorphism array in 347 de novo diffuse large B-cell lymphoma cases.

  2. findings suggest that expression of cFLIPL regulates the basal interaction of Bcl-2 with Beclin-1 (Montrer BECN1 Anticorps) and substantiates p53 (Montrer TP53 Anticorps) dependent ubiquitination of Beclin-1 (Montrer BECN1 Anticorps) during autophagic stress to determine the fate of cell death or survival.

  3. Our findings suggest that RACK1 (Montrer GNB2L1 Anticorps) promotes proliferation and radioresistance in ESCC cells by activating the AKT (Montrer AKT1 Anticorps) pathway, upregulating Bcl-2 expression and downregulating protein levels of Bim (Montrer BCL2L11 Anticorps). Our study fills in gaps in the field of RACK1 (Montrer GNB2L1 Anticorps) and radiation resistance and may provide new possibilities for improving strategies of radiotherapy in esophageal cancer.

  4. Western blot analysis and quantitative real-time polymerase chain reaction demonstrated reduced expression of pri-miR (Montrer MLXIP Anticorps)-211, miR (Montrer MLXIP Anticorps)-211, TRPM1 (Montrer TRPM1 Anticorps), and MLANA (Montrer MLANA Anticorps) levels, after Bcl-2 overexpression, associated with increased expression of well-known miR (Montrer MLXIP Anticorps)-211 target genes.

  5. this study elucidated mechanisms of BCL2 overexpression and association of this survival pathway with the BCR (Montrer BCR Anticorps)/BTK (Montrer BTK Anticorps) signaling pathway in MCL (Montrer FH Anticorps), and revealed the role of BTK (Montrer BTK Anticorps) in noncanonical NF-kappaB (Montrer NFKB1 Anticorps) activation, which also promotes cancer cell survival.

  6. Follicular lymphoma with MYC (Montrer MYC Anticorps) and BCL2 translocations, so-called double-hit follicular lymphoma (DH-FL), is part of the spectrum of double-hit high-grade lymphoma.

  7. we propose that the existing controversy reflects the diversity of links between Bcl-2 proteins and Ca(2 (Montrer CA2 Anticorps)+) signaling, as certainly not all targets or mechanisms will be operative in every cell type and every condition.

  8. Overview of the pleiotropic functions of BCL2 mediated by its physical binding interaction with other proteins and the various ways BCL2 mutations would affect the normal function of the cell leading to the development of diffuse large B-cell lymphomas (review).

  9. Diffuse large B-cell lymphoma with concurrent high MYC (Montrer MYC Anticorps) and BCL2 expression shows evidence of active B-cell receptor signaling

  10. Case Reports: BCL2 gene translocations are a recurrent feature of a distinct subset of histiocytic sarcomas that are associated with follicular lymphoma.

Cow (Bovine) B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. Over-expression of STC-1 (Montrer STC1 Anticorps) up-regulated Bcl-2 protein expression and slightly down-regulated caspase-3 (Montrer CASP3 Anticorps) production in the damaged cells. Findings from this study suggest that STC-1 (Montrer STC1 Anticorps) plays a protective role in intestinal cells through an antioxidant mechanism.

  2. BoHV-5 replication apparently modulates BCL-2 expression and gene transcription, enhancing production of virus progeny, but does not increase Bax (Montrer BAX Anticorps) expression.

  3. G3139, a BCL-2 antisesnse oligonucleotide is a promising candidate for treatment of patients with imatinib-resistant Ph-positive leukemia.

  4. role of vascular endothelial growth factor receptor-1 (Montrer FLT1 Anticorps) in Bcl-2 expression

  5. apoptosis-inducing factor (Montrer AIFM1 Anticorps) was expressed in luminal alveolar cells and, in concert with a change in bax (Montrer BAX Anticorps) protein to bcl-2 protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses

  6. mRNA expression of Bax (Montrer BAX Anticorps), Bcl-2, caspase-3 (Montrer CASP3 Anticorps) and-7 cannot be used as a reliable apoptosis detection method.

  7. These results propose an additional mechanism whereby resveratrol may exert its cardioprotective effects and suggest a key role for Bcl-2 in the resveratrol anti-apoptotic action, especially in disrupting peroxynitrite-triggered mitochondrial pathway.

Rabbit B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. excessive apoptosis does occur in acetabular cartilage with developmental dislocations of the hip, and is positively correlated with high caspase-3 (Montrer CASP3 Anticorps) expression as well as low Bcl-2 expression.

  2. These results indicate that RI-PostC can ameliorate myocardial ischemia-reperfusion injury and increase the Bcl-2/Bax (Montrer BAX Anticorps) ratio through a mechanism involving protein kinase C (Montrer PKC Anticorps).

  3. Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax (Montrer BAX Anticorps) and decreasing expression of bcl2.

  4. Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 and increased expression of Bax (Montrer BAX Anticorps).

  5. Our data indicate that exposure to rabbits to Pb(Ac)(2) caused a significant increase of apoptosis protein p53 (Montrer TP53 Anticorps) and decrease in the antiapoptotic BCl2 proteins.

  6. Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 and down-regulating the activation of caspase-3 (Montrer CASP3 Anticorps).

  7. Data show that the damaged electron transport chain leads to bcl-2 depletion and MPT opening.

Zebrafish B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. These results suggest a role for mitochondrial p53 (Montrer TP53 Anticorps) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax (Montrer BAX Anticorps) and Bcl2.

  2. Zebrafish gene expressions of P53 (Montrer TP53 Anticorps), Bcl-2, Bax (Montrer BAX Anticorps) and caspase-3 (Montrer CASP3 Anticorps) were elevated after exposure with microcystin-LR under different ambient temperatures.

  3. Analysis using clinical biopsy specimens revealed autophagy and increased levels of BCL2, S1P1 (Montrer S1PR1 Anticorps), and ICAM1 (Montrer ICAM1 Anticorps) in human T-lymphoblastic lymphoma compared with T-lymphoblastic leukemia.

  4. Real-time RT-PCR revealed acetaminophen treatment of zebrafish embryos decreased the expression of cox2 (Montrer COX2 Anticorps) and bcl2, but increased p53 (Montrer TP53 Anticorps) expression.

  5. Leukemia onset was dramatically accelerated in transgenic fish overexpressing human Notch1 (Montrer NOTCH1 Anticorps) and fish bcl-2, indicating synergy between the Notch (Montrer NOTCH1 Anticorps) pathway and the bcl2-mediated antiapoptotic pathway.

BCL2 profil antigène

Antigen Summary

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.

Alternative names and synonyms associated with BCL2

  • B-cell CLL/lymphoma 2 (BCL2) anticorps
  • B-cell CLL/lymphoma 2 (Bcl2) anticorps
  • B-cell CLL/lymphoma 2 (LOC100224888) anticorps
  • B cell leukemia/lymphoma 2 (Bcl2) anticorps
  • B-cell leukemia/lymphoma 2 (bcl2) anticorps
  • B-cell leukemia/lymphoma 2-like (LOC100359045) anticorps
  • B-cell CLL/lymphoma 2 protein (BCL-2) anticorps
  • AW986256 anticorps
  • BCL-2 anticorps
  • Bcl2 anticorps
  • C430015F12Rik anticorps
  • D630044D05Rik anticorps
  • D830018M01Rik anticorps
  • PPP1R50 anticorps

Protein level used designations for BCL2

apoptosis regulator Bcl-2 , protein phosphatase 1, regulatory subunit 50 , B cell lymphoma 2 associated oncogene , B-cell leukemia/lymphoma 2 , Bcl2-like protein , PCKBCL2 , BCL2B-cell CLL/lymphoma 2 , B-cell lymphoma protein 2 , Bcl2 , zBlp2 , B-cell CLL/lymphoma 2

GENE ID SPECIES
596 Homo sapiens
24224 Rattus norvegicus
396282 Gallus gallus
493934 Felis catus
738409 Pan troglodytes
100224888 Taeniopygia guttata
100049703 Sus scrofa
12043 Mus musculus
570772 Danio rerio
403416 Canis lupus familiaris
281020 Bos taurus
100733337 Cavia porcellus
100359045 Oryctolagus cuniculus
100009447 Oryctolagus cuniculus
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