anti-Poulet ERK2 anticorps pour Immunoprecipitation

Recommended ERK2 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Mitogen-Activated Protein Kinase 1 (MAPK1) Anticorps
  • ATMPK1
  • F14N23.9
  • F14N23_9
  • MITOGEN-ACTIVATED PROTEIN KINASE
  • mitogen-activated protein kinase 1
  • ATMPK2
  • MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2
  • T30E16.13
  • T30E16_13
  • mitogen-activated protein kinase homolog 2
  • ERK2
  • zERK2
  • MAPK1
  • ERK
  • ERT1
  • MAPK2
  • P42MAPK
  • PRKM1
  • PRKM2
  • p38
  • p40
  • p41
  • p41mapk
  • 9030612K14Rik
  • AA407128
  • AU018647
  • C78273
  • Erk2
  • Prkm1
  • p42mapk
  • erk
  • erk2
  • ert1
  • mapk
  • mpk1
  • xp42
  • mapk2
  • prkm1
  • prkm2
  • Xp42
  • mapk1b
  • mapk1
  • mapk1a
  • mitogen-activated protein kinase 1
  • mitogen-activated protein kinase 2
  • mitogen activated protein kinase 1
  • ATMPK1
  • MPK1
  • MPK2
  • MAPK1
  • mapk1
  • Mapk1
  • PfMAP1
  • PVX_084965
  • Tsp_01601
  • mapk1-b
  • mapk1-a
Épitope
AA 219-358
61
21
16
11
9
9
8
8
5
5
4
4
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivité
Poulet, Chien, Grenouille, Humain, Souris, Rat (Rattus)
355
148
119
50
30
19
14
10
10
9
8
7
5
5
2
2
2
2
1
1
1
1
Hôte
Souris
171
167
17
8
3
Clonalité
Monoclonal
Conjugué
Cet anticorp ERK2 est non-conjugé
10
9
8
7
4
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
329
157
96
83
82
62
52
26
22
10
5
3
3
2
2
1
1
1
1
1
1
1
1
Options
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N° du produit ABIN967747
Produit non disponible pour cette région.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN967748 IF IP IHC WB Mouse IgG2b AA 219-358 Connectez-vous pour afficher 33-ERK2 5

General

Antigène Mitogen-Activated Protein Kinase 1 (MAPK1) Anticorps
Épitope AA 219-358
(61), (21), (16), (11), (9), (9), (8), (8), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Poulet, Chien, Grenouille, Humain, Souris, Rat (Rattus)
(355), (148), (119), (50), (30), (19), (14), (10), (10), (9), (8), (7), (5), (5), (2), (2), (2), (2), (1), (1), (1), (1)
Hôte Souris
(171), (167), (17), (8), (3)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp ERK2 est non-conjugé
(10), (9), (8), (7), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(329), (157), (96), (83), (82), (62), (52), (26), (22), (10), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-ERK2 anticorps

Détail du antigène ERK2 Information d'application Stockage References for anti-ERK2 antibody (ABIN967747) Images
 Réactivité croisée Humain, Chien, Souris, Poulet, Grenouille
Attributs du produit 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogène Rat ERK2 aa. 219-358
Clone 33-ERK2
Isotype IgG2b

Détail du antigène ERK2

Détail du produit anti-ERK2 anticorps Information d'application Stockage References for anti-ERK2 antibody (ABIN967747) Images Haut de la page
Antigène
Autre désignation ERK2 (MAPK1 Antibody Extrait)
Sujet The family of serine/threonine kinases known as ERKs (extracellular signal regulated kinases) or MAPKs (mitogen-activated protein kinases) are activated after cell stimulation by a wide variety of hormones and growth factors. Cell stimulation induces a signaling cascade that leads to phosphorylation of MEK (MAPK/ERK kinase) which, in turn, activates ERK via tyrosine and threonine phosphorylation. Structural analysis of ERK2 indicates that phosphorylation induces a conformational change that exposes the active site for substrate binding. Myriad proteins represent the downstream effectors for the active ERK and implicate it in the control of cell proliferation and differentiation, as well as regulation of the cytoskeleton. Activation of ERK is normally transient and cells possess dual specificity phosphatases that are responsible for its down-regulation. Furthermore, multiple studies have shown that elevated ERK activity is associated with some cancers. ERK2 is the 42kDa member of the ERK family and is highly homologous to ERK1.
Poids moléculaire 42 kDa
Domaine de recherche Stem Cells, Signaling, Inflammation
Pathways Signalisation MAPK, Signalisation RTK, Apoptose, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals

Information d'application

Détail du produit anti-ERK2 anticorps Détail du antigène ERK2 Stockage References for anti-ERK2 antibody (ABIN967747) Images Haut de la page
Commentaires

Related Products: ABIN967389

Restrictions For Research Use only

Stockage

Détail du produit anti-ERK2 anticorps Détail du antigène ERK2 Information d'application References for anti-ERK2 antibody (ABIN967747) Images Haut de la page
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store undiluted at -20°C.

References for anti-ERK2 antibody (ABIN967747)

Détail du produit anti-ERK2 anticorps Détail du antigène ERK2 Information d'application Stockage Images Haut de la page
Produit citée dans:

Kim, Ju, Oh, Yoon, Song, Kim, Yoo, Bang, Kang, Chun: "ERK-1/2 and p38 kinase oppositely regulate nitric oxide-induced apoptosis of chondrocytes in association with p53, caspase-3, and differentiation status." dans: The Journal of biological chemistry, Vol. 277, Issue 2, pp. 1332-9, 2002

Lund-Johansen, Davis, Bishop, de Waal Malefyt: "Flow cytometric analysis of immunoprecipitates: high-throughput analysis of protein phosphorylation and protein-protein interactions." dans: Cytometry, Vol. 39, Issue 4, pp. 250-9, 2000

Lehmann, Janda, Pierreux, Rytömaa, Schulze, McMahon, Hill, Beug, Downward: "Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells." dans: Genes & development, Vol. 14, Issue 20, pp. 2610-22, 2000

Liu, Tsai, Aird: "Egr-1 gene is induced by the systemic administration of the vascular endothelial growth factor and the epidermal growth factor." dans: Blood, Vol. 96, Issue 5, pp. 1772-81, 2000

Visconti, Gadina, Chiariello, Chen, Stancato, Gutkind, OShea: "Importance of the MKK6/p38 pathway for interleukin-12-induced STAT4 serine phosphorylation and transcriptional activity." dans: Blood, Vol. 96, Issue 5, pp. 1844-52, 2000

Images

Détail du produit anti-ERK2 anticorps Détail du antigène ERK2 Information d'application Stockage References for anti-ERK2 antibody (ABIN967747) Haut de la page
Supplier Images
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 219-358) antibody (ABIN967747) Western blot analysis of ERK2 on rat pituitary lysate. Lane 1: 1:5000, lane 2: 1:1000...
Immunofluorescence (IF) image for anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 219-358) antibody (ABIN967747) Immunofluorescence staining of MCF7 cells.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 219-358) antibody (ABIN967747) ERK 2 (clone 33) staining on rat brain. Formalin fixed paraffin section with citrate ...