anti-Souris ERK2 anticorps pour Intracellular Staining

Recommended ERK2 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Mitogen-Activated Protein Kinase 1 (MAPK1) Anticorps
  • ATMPK1
  • F14N23.9
  • F14N23_9
  • MITOGEN-ACTIVATED PROTEIN KINASE
  • mitogen-activated protein kinase 1
  • ATMPK2
  • MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2
  • T30E16.13
  • T30E16_13
  • mitogen-activated protein kinase homolog 2
  • ERK2
  • zERK2
  • MAPK1
  • ERK
  • ERT1
  • MAPK2
  • P42MAPK
  • PRKM1
  • PRKM2
  • p38
  • p40
  • p41
  • p41mapk
  • 9030612K14Rik
  • AA407128
  • AU018647
  • C78273
  • Erk2
  • Prkm1
  • p42mapk
  • erk
  • erk2
  • ert1
  • mapk
  • mpk1
  • xp42
  • mapk2
  • prkm1
  • prkm2
  • Xp42
  • mapk1b
  • mapk1
  • mapk1a
  • mitogen-activated protein kinase 1
  • mitogen-activated protein kinase 2
  • mitogen activated protein kinase 1
  • ATMPK1
  • MPK1
  • MPK2
  • MAPK1
  • mapk1
  • Mapk1
  • PfMAP1
  • PVX_084965
  • Tsp_01601
  • mapk1-b
  • mapk1-a
Reactivité
Humain, Souris
355
148
120
50
31
19
14
11
10
9
8
7
5
5
2
2
2
2
2
1
1
1
Hôte
Souris
171
167
17
8
3
Clonalité
Monoclonal
Conjugué
Cet anticorp ERK2 est conjugé à/à la PE
10
9
7
7
4
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
Application
Intracellular Staining (ICS)
330
157
97
84
82
63
52
26
22
10
5
3
2
2
2
1
1
1
1
1
1
1
1
Options
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N° du produit ABIN1176892
Produit non disponible pour cette région.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN1176893 ICS Alexa Fluor 647 Mouse IgG1, kappa Connectez-vous pour afficher G263-7 1
1 ABIN1176894 ICS Alexa Fluor 488 Mouse IgG1, kappa Connectez-vous pour afficher G263-7 4

General

Antigène Mitogen-Activated Protein Kinase 1 (MAPK1) Anticorps
Reactivité Humain, Souris
(355), (148), (120), (50), (31), (19), (14), (11), (10), (9), (8), (7), (5), (5), (2), (2), (2), (2), (2), (1), (1), (1)
Hôte Souris
(171), (167), (17), (8), (3)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp ERK2 est conjugé à/à la PE
(10), (9), (7), (7), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1)
Application Intracellular Staining (ICS)
(330), (157), (97), (84), (82), (63), (52), (26), (22), (10), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 référence disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-ERK2 anticorps

Détail du antigène ERK2 Information d'application Stockage References for anti-ERK2 antibody (ABIN1176892) Images
Marque BD Phosflow™
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogène Human ERK2 Synthetic Peptide
Clone G263-7
Isotype IgG1, kappa

Détail du antigène ERK2

Détail du produit anti-ERK2 anticorps Information d'application Stockage References for anti-ERK2 antibody (ABIN1176892) Images Haut de la page
Antigène
Autre désignation ERK2 (MAPK1 Antibody Extrait)
Sujet The members of the Mitogen-Activated Protein Kinase (MAPK) family are components of a key signal transduction cascade that links events at the cell surface to responses in the nucleus. The signaling cascade is found in species as varied as yeast and humans, with many of the proteins being well conserved. In mammals the most widely studied members of the cascade are the Extracellular signal-Regulated Kinases, ERK1 (p44 MAPK) and ERK2 (p42 MAPK). ERK1 and ERK2 share 85% homology and are activated by extracellular signals such as growth factors, hormones, and phorbol esters. Activation occurs through a series of phosphorylations by kinases activating other kinases and eventually leading to phosphorylation of the ERKs. Growth factor stimulation leads to activation of Ras and Raf, leading to phosphorylation of MEK1 (MAPK/ERK kinase) which, in turn, activates the ERKs via dual phosphorylation. Once activated, the ERKs phosphorylate other cytoplasmic signaling molecules (protein kinases and phosphatases), cell-surface receptors, microtubule-associated proteins, and transcription factors in the nucleus. Thus, the active ERK has myriad downstream effectors that implicate it in the control of cell proliferation and differentiation, as well as regulation of the cytoskeleton. Furthermore, studies have shown that elevated ERK activity is associated with some cancers. The G263-7 recognizes ERK2. It does not cross-react with ERK1. Clone G263-7 was originally characterized in human (A431) and mouse (NIH/3T3) cells. A human ERK2 synthetic peptide was used as immunogen.
Domaine de recherche Inflammation
Pathways Signalisation MAPK, Signalisation RTK, Apoptose, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals

Information d'application

Détail du produit anti-ERK2 anticorps Détail du antigène ERK2 Stockage References for anti-ERK2 antibody (ABIN1176892) Images Haut de la page
Volume d'échantillon 20 μL
Restrictions For Research Use only

Stockage

Détail du produit anti-ERK2 anticorps Détail du antigène ERK2 Information d'application References for anti-ERK2 antibody (ABIN1176892) Images Haut de la page
Format Liquid
Buffer Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.

References for anti-ERK2 antibody (ABIN1176892)

Détail du produit anti-ERK2 anticorps Détail du antigène ERK2 Information d'application Stockage Images Haut de la page
Produit citée dans:

Treisman: "Regulation of transcription by MAP kinase cascades." dans: Current opinion in cell biology, Vol. 8, Issue 2, pp. 205-15, 1996

Images

Détail du produit anti-ERK2 anticorps Détail du antigène ERK2 Information d'application Stockage References for anti-ERK2 antibody (ABIN1176892) Haut de la page
Supplier Images
Flow Cytometry (FACS) image for anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibody (PE) (ABIN1176892) anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibody (PE)