Aperçu des produits pour anti-JNK (MAPK8) Anticorps

Full name:
anti-Mitogen-Activated Protein Kinase 8 Anticorps (MAPK8)
Chez www.anticorps-enligne.fr sont 413 Mitogen-Activated Protein Kinase 8 (MAPK8) Anticorps de 35 de différents fournisseurs disponibles. De plus, nous expédions JNK Protéines (25) et JNK Kits (23) et beaucoup plus de produits pour cette protéine. Un total de 495 JNK produits sont actuellement listés.
Synonymes:
AI849689, Bsk, BSK/DJNK, c-Jun, CG5680, D-JNK, D-junk, DBSK/JNK, dJNK, DJNK/bsk, Dmel\\CG5680, jnk, JNK-46, JNK/SAPK, jnk1, JNK1A2, JNK21B1/2, Junk, mapk8, Prkm8, sapk1, SAPK1c, SAPKa, T10F20.15, zgc:112379

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anti-JNK Anticorps mieux référencés

  1. Human Monoclonal JNK Primary Antibody pour IP, WB - ABIN967329 : Adler, Fuchs, Kim, Kraft, King, Pelling, Ronai: jun-NH2-terminal kinase activation mediated by UV-induced DNA lesions in melanoma and fibroblast cells. dans Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996 (PubMed)
    Show all 8 references for 967329

  2. Human Polyclonal JNK Primary Antibody pour IF, IHC (p) - ABIN391724 : Deng, Ren, Yang, Lin, Wu: A JNK-dependent pathway is required for TNFalpha-induced apoptosis. dans Cell 2003 (PubMed)
    Show all 6 references for 391724

  3. Human Polyclonal JNK Primary Antibody pour EIA - ABIN358374 : Luo, Ng, Jin, Ye, Han, Lin: Axin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activation. dans The Journal of biological chemistry 2003 (PubMed)
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  4. Human Polyclonal JNK Primary Antibody pour EIA, IHC (p) - ABIN953314 : Dasgupta, Kar, Liu, Joseph, Kalyanaraman, Remington, Chen, Melendez: Reactive oxygen species control senescence-associated matrix metalloproteinase-1 through c-Jun-N-terminal kinase. dans Journal of cellular physiology 2010 (PubMed)
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  5. Human Polyclonal JNK Primary Antibody pour EIA, WB - ABIN359636 : Ghosh: Inhibition of arachidonate 5-lipoxygenase triggers prostate cancer cell death through rapid activation of c-Jun N-terminal kinase. dans Biochemical and biophysical research communications 2003 (PubMed)
    Show all 5 references for 359636

  6. Human Monoclonal JNK Primary Antibody pour FACS, WB - ABIN968866 : Fleming, Armstrong, Morrice, Paterson, Goedert, Cohen: Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7. dans The Biochemical journal 2001 (PubMed)
    Show all 4 references for 968866

  7. Human Polyclonal JNK Primary Antibody pour IF, WB - ABIN401562 : Davis: Signal transduction by the c-Jun N-terminal kinase. dans Biochemical Society symposium 1999 (PubMed)
    Show all 3 references for 401562

  8. Human Polyclonal JNK Primary Antibody pour IHC (p), WB - ABIN654887 : Han, Crowe: Jun amino-terminal kinase 1 activation promotes cell survival in ErbB2-positive breast cancer. dans Anticancer research 2010 (PubMed)
    Show all 3 references for 654887

  9. Human Polyclonal JNK Primary Antibody pour IHC, IHC (p) - ABIN4327961 : Gao, Wang, Zhang, Yu, Ji, Wang, Zhang, Jiang, Jin, Huang, Zhang, Li: Tumor necrosis factor receptor-associated factor 5 (Traf5) acts as an essential negative regulator of hepatic steatosis. dans Journal of hepatology 2016 (PubMed)
    Show all 2 references for 4327961

  10. Human Monoclonal JNK Primary Antibody pour WB - ABIN2452243 : Sung, Liang, Lee, Yen, Hsiao, Wang, Jiang-Shieh, Tsai, Chen: The protective effect of eupafolin against TNF-?-induced lung inflammation via the reduction of intercellular cell adhesion molecule-1 expression. dans Journal of ethnopharmacology 2015 (PubMed)

Plus d’anticorps contre JNK partenaires d’interaction

Fruit Fly (Drosophila melanogaster) Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. Here we uncover a cell non-autonomous requirement for the Epidermal growth factor receptor (Egfr (Montrer EGFR Anticorps)) pathway in the lateral epidermis for sustained dpp (Montrer TGFb Anticorps) expression in the LE. Specifically, we demonstrate that Egfr (Montrer EGFR Anticorps) pathway activity in the lateral epidermis prevents expression of the gene scarface (scaf), encoding a secreted antagonist of JNK signaling

  2. n addition to significantly increasing the number of JNK target genes identified so far, our results reveal that the LE is a highly heterogeneous morphogenetic organizer, sculpted through crosstalk between JNK, segmental and AP signalling. This fine-tuning regulatory mechanism is essential to coordinate morphogenesis and dynamics of tissue sealing

  3. malignant transformation of the ras(V12)scrib(1 (Montrer SCRIB Anticorps)) tumors requires bZIP protein Fos, the ETS (Montrer ETS1 Anticorps)-domain factor Ets21c and the nuclear receptor Ftz-F1 (Montrer NR5A2 Anticorps), all acting downstream of Jun-N-terminal kinase.

  4. Diminished MTORC1-dependent JNK activation underlies the neurodevelopmental defects associated with lysosomal dysfunction.

  5. ROS (Montrer ROS1 Anticorps)/JNK/p38 (Montrer MAPK14 Anticorps)/Upd (Montrer UROD Anticorps) stress responsive module restores tissue homeostasis. This module is not only activated after cell death induction but also after physical damage and reveals one of the earliest responses for imaginal disc regeneration.

  6. Significantly, the JNK pathway is responsible for the majority of the phenotypes and transcriptional changes downstream of Notch (Montrer NOTCH1 Anticorps)-Src (Montrer SRC Anticorps) synergy.

  7. This study demonstrated that the mechanism by which Bsk (Montrer FRK Anticorps) is required for pruning is through reducing the membrane levels of the adhesion molecule (Montrer NCAM1 Anticorps) Fasciclin II (Montrer NCAM2 Anticorps) (FasII)

  8. Study solves the crystal structure of unphosphorylated DJNK in complex with adenylyl imidodiphosphate (AMP (Montrer AMPH Anticorps)-PNP (Montrer NP Anticorps)) and magnesium.

  9. PERK/ATF4 activated the JNK pathway through Rac1 and Slpr activation in apoptotic cells.

  10. Data show that oxidative stress and neuroinflammation are intrinsic components of TDP-43 (Montrer TARDBP Anticorps)-associated neurodegeneration and the balance between cytoprotective JNK and cytotoxic p38 (Montrer MAPK14 Anticorps) signaling dictates phenotypic outcome to TDP-43 (Montrer TARDBP Anticorps) expression in Drosophila.

Human Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. Here, the authors show that the CDK (Montrer CDK4 Anticorps) inhibitor p21 (CDKN1A (Montrer CDKN1A Anticorps)) maintains the viability of DNA damage-induced senescent cells. Upon p21 (Montrer CDKN1A Anticorps) knockdown, senescent cells acquired multiple DNA lesions that activated ataxia telangiectasia mutated (ATM (Montrer ATM Anticorps)) and nuclear factor (NF)-kappaB (Montrer NFKB1 Anticorps) kinase, leading to decreased cell survival. NF-kappaB (Montrer NFKB1 Anticorps) activation induced TNF-alpha (Montrer TNF Anticorps) secretion and JNK activation to mediate death of senescent cells in a...

  2. Results indicate that cordycepin promotes caveolin-1 (CAV1 (Montrer CAV1 Anticorps))upregulation to enhance c-jun N-terminal kinase (JNK)/forkhead box O3A (Montrer FOXO3 Anticorps) protein (Foxo3a (Montrer FOXO3 Anticorps)) signaling pathway activation, inducing apoptosis in lung cancer cells.

  3. The combination of 2-deoxyglucose (2-DG) and ABT-199 initiated cell death through the reduction of myeloid cell leukemia sequence 1 protein (Mcl-1 (Montrer MCL1 Anticorps)) expression and c-Jun N-terminal kinase 1 (JNK1) activation and subsequent Bcl-xL (Montrer BCL2L1 Anticorps) protein degradation.

  4. identified the c-Jun N-terminal kinase 1 (JNK1) as the kinase involved in the phosphorylation of NEIL1 (Montrer NEIL1 Anticorps)

  5. This study suggests that advanced glycation end products (AGEs) and activation of AGEs receptor could induce the proliferation of smooth muscle cells from Saphenous vein but not smooth muscle cells from internal thoracic arteryvia MAP kinase (Montrer MAPK1 Anticorps) pathway in diabetes mellitus.

  6. The increase in c-Jun N-terminal kinase (c-Jun) and specificity protein 1 (SP1 (Montrer SP1 Anticorps)) expressions was positively correlated with transforming growth factor beta 1 (TGFbeta1 (Montrer TGFB1 Anticorps)) in both high glucose-treated renal mesangial cells (HRMCs) and diabetic kidneys.

  7. JNK1 physically and functionally interacted with VDR (Montrer CYP27B1 Anticorps) and positively regulated VDR (Montrer CYP27B1 Anticorps) expression at transcriptional and translational levels, which influenced calcitriol-mediated inhibition of cancer cell proliferation.

  8. In conclusion, our findings revealed DIP2 (Montrer WDR3 Anticorps) as a novel effector downstream of Bsk (Montrer FRK Anticorps) modulating the direction of axon projection.

  9. The release of infectious respiratory syncytial virus (RSV) virions from infected cells was significantly reduced by JNK1/2 siRNA knockdown, implicating JNK1/2 as a key host factor for RSV virus production.

  10. dMyc has an essential role in preventing JNK-mediated retinal glial activation

Mouse (Murine) Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. It was concluded that compounds targeting JNK1 activity in brain and adipose tissue, which do not accumulate in the skin, may be safer and most effective.

  2. JNK1 activation suppresses antifungal immunity in mice. JNK1-deficient mice had a significantly higher survival rate than wild-type control mice in response to Candida albicans infection, and the expression of JNK1 in hematopoietic innate immune cells was critical for this effect.

  3. activation of JNK in the endoplasmic reticulum stress response precedes activation of XBP1 (Montrer XBP1 Anticorps).

  4. Data suggest that single muscle immobilization induces a shift of myosin heavy chain (MHC) isoforms composition toward a faster contractile phenotype and decreases the polymorphic profile of single fibres, and that activation of p38 and JNK could be a potential mechanism involved in these contractile phenotype modifications during muscle immobilization.

  5. JNK/FoxO1 (Montrer FOXO1 Anticorps) is involved in the regulation of oxidative stress-induced (Montrer SQSTM1 Anticorps) cell apoptosis in MGCs

  6. apoE (Montrer APOE Anticorps)(-/-) mouse carrying a visceral fat graft from obese dnJNK donors were protected against enhanced systemic inflammation and atherogenesis.

  7. These data provide evidence for involvement of the TNF-alpha (Montrer TNF Anticorps)-JNK axis in extracellular matrix remodeling.

  8. Phosphorylation levels of P38 (Montrer CRK Anticorps) and JNK in siRNA-TMEM16A (Montrer ANO1 Anticorps) group were lower than that of the Model group. Thus, TMEM16A (Montrer ANO1 Anticorps) is one of the critical components of a signal transduction pathway that links renal injury to podocyte apoptosis in DN.

  9. Loss of Jnk1, but not Jnk2 (Montrer MAPK9 Anticorps), in macrophages protects them from apoptosis, increasing cell survival, and this accelerates early atherosclerosis in LDL receptor (Montrer LDLR Anticorps) knockout mice.

  10. Data indicate that in baicalein (BAI)-treated groups following AngII-infusion, p38-MAPK (Montrer MAPK14 Anticorps) and JNK signaling were attenuated

Xenopus laevis Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. Hyperosmotic Shock Engages Two Positive Feedback Loops through Caspase-3 (Montrer CASP3 Anticorps)-dependent Proteolysis of JNK1-2 and Bid (Montrer BID Anticorps).

  2. JNK signaling is required to establish microtubule stability and maintain tissue cohesion in the gut (Montrer GUSB Anticorps).

  3. Data show that the death pathway is independent of ERK (Montrer MAPK1 Anticorps) but relies on activating Bad phosphorylation through the control of both kinases Cdk1 (Montrer CDK1 Anticorps) and JNK.

Arabidopsis thaliana Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. study reports MPK8 connects protein phosphorylation, Ca(2 (Montrer CA2 Anticorps))+ and ROS (Montrer ROS1 Anticorps) in wound-signaling pathway; suggests 2 major activation modes, Ca(2 (Montrer CA2 Anticorps))+/CaMs and MAP kinase (Montrer MAPK1 Anticorps) phosphorylation cascade, converge at MPK8 to monitor or maintain an essential part of ROS (Montrer ROS1 Anticorps) homeostasis

Zebrafish Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. our data provide strong evidence that Jip3 in fact serves as an adapter protein linking these cargos to dynein

  2. P38 (Montrer MAPK14 Anticorps) and JNK have opposing effects on persistence of in vivo leukocyte migration in zebrafish.

  3. A dorsalization pathway that is exerted by Axin (Montrer AXIN1 Anticorps)/JNK signaling and its inhibitor Aida (Montrer AIDA Anticorps) during vertebrate embryogenesis, is defined.

  4. JNK-Mmp13 (Montrer MMP13 Anticorps) signaling pathway plays an essential role in regulating the innate immune cell migration in response to severe injury in vivo

Caenorhabditis elegans (C. elegans) Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. Our genetic study unravelled the underlying pathway where JNK-1 is acting independently of insulin (Montrer INS Anticorps)-IGF-1 (Montrer IGF1 Anticorps) signalling (IIS) pathway to modulate longevity. In support of in vivo results in silico docking study of UA with C. elegans JNK-1 ATP-binding site suggested promising binding affinity exhibiting binding energy of -8.11 kcalmol(-1). UA induced JNK-1 activation in wild-type animals underlie the importance of pharmacologi

  2. JNK-1 directly interacts with and phosphorylates DAF-16. Moreover, in response to heat stress, JNK-1 promotes the translocation of DAF-16 into the nucleus.

  3. The present study shows in Caenorhabditis elegans that ambient temperature (1-37 degrees C) specifically influences the activation (phosphorylation) of the MAP kinase JNK-1 as well as the nuclear translocation of DAF-16.

  4. the stress response is controlled by a c-Jun N-terminal kinase (JNK)-like mitogen-activated protein kinase (Montrer MAPK1 Anticorps) (MAPK (Montrer MAPK1 Anticorps)) signaling pathway, which is regulated by MLK-1 (Montrer MAP3K9 Anticorps) MAPK (Montrer MAPK1 Anticorps) kinase kinase (MAPKKK), MEK-1 (Montrer MAP2K1 Anticorps) MAPK (Montrer MAPK1 Anticorps) kinase (MAPKK), and KGB-1 (Montrer KCNJ3 Anticorps) JNK-like MAPK (Montrer MAPK1 Anticorps).

JNK (MAPK8) profil antigène

Antigen Summary

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with JNK (MAPK8)

  • basket (bsk) anticorps
  • mitogen-activated protein kinase 8 (MAPK8) anticorps
  • mitogen-activated protein kinase 8 (Mapk8) anticorps
  • mitogen-activated protein kinase 8 (mapk8) anticorps
  • mitogen-activated protein kinase 8 (ATMPK8) anticorps
  • mitogen-activated protein kinase 8b (mapk8b) anticorps
  • Protein JNK-1 (jnk-1) anticorps
  • AI849689 anticorps
  • Bsk anticorps
  • BSK/DJNK anticorps
  • c-Jun anticorps
  • CG5680 anticorps
  • D-JNK anticorps
  • D-junk anticorps
  • DBSK/JNK anticorps
  • dJNK anticorps
  • DJNK/bsk anticorps
  • Dmel\\CG5680 anticorps
  • jnk anticorps
  • JNK-46 anticorps
  • JNK/SAPK anticorps
  • jnk1 anticorps
  • JNK1A2 anticorps
  • JNK21B1/2 anticorps
  • Junk anticorps
  • mapk8 anticorps
  • Prkm8 anticorps
  • sapk1 anticorps
  • SAPK1c anticorps
  • SAPKa anticorps
  • T10F20.15 anticorps
  • zgc:112379 anticorps

Protein level used designations for MAPK8

CG5680-PB , CG5680-PE , CG5680-PF , JNK , JUN kinase , Jun N-terminal kinase , Jun NH2-terminal kinase , Jun-N-terminal kinase , Jun-kinase , bsk-PB , bsk-PE , bsk-PF , c-Jun N-terminal kinase , c-Jun aminoterminal kinase , c-Jun-N-terminal kinase , drosophila JNK , JUN N-terminal kinase , MAP kinase 8 , c-Jun N-terminal kinase 1 , mitogen-activated protein kinase 8 isoform JNK1 alpha1 , mitogen-activated protein kinase 8 isoform JNK1 beta2 , stress-activated protein kinase 1 , stress-activated protein kinase 1c , JNK1 beta1 protein kinase , MAPK 8 , mitogen activated protein kinase 8 , protein kinase mitogen-activated 8 , stress-activated protein kinase JNK1 , SAPK gamma , c-jun NH2-terminal kinase , p54 gamma , jnk1a-1 , mitogen-activated protein kinase 8

GENE ID SPECIES
44801 Drosophila melanogaster
5599 Homo sapiens
26419 Mus musculus
116554 Rattus norvegicus
379876 Xenopus laevis
838394 Arabidopsis thaliana
65236 Danio rerio
177460 Caenorhabditis elegans
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