Aperçu des produits pour anti-MAP2K1 (MAP2K1) Anticorps

Full name:
anti-Mitogen-Activated Protein Kinase Kinase 1 Anticorps (MAP2K1)
Chez www.anticorps-enligne.fr sont 628 Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) Anticorps de 32 de différents fournisseurs disponibles. De plus, nous expédions MAP2K1 Kits (31) et MAP2K1 Protéines (22) et beaucoup plus de produits pour cette protéine. Un total de 721 MAP2K1 produits sont actuellement listés.
Synonymes:
ATMEK1, CFC3, F20B18.180, F20B18_180, MAP kinase/ ERK kinase 1, MAPKK1, MEK, mek-2, MEK1, MEKK1, MITOGEN ACTIVATED PROTEIN KINASE KINASE, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1, MKK1, NMAPKK, Prkmk1, si:ch211-242m18.2, wu:fj56a12, wu:fj61b01, zgc:56557

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anti-MAP2K1 Anticorps mieux référencés

  1. Human Monoclonal MAP2K1 Primary Antibody pour IP, WB - ABIN2853620 : Riesmeier, Willmitzer, Frommer: Evidence for an essential role of the sucrose transporter in phloem loading and assimilate partitioning. dans The EMBO journal 1994 (PubMed)
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  2. Chicken Monoclonal MAP2K1 Primary Antibody pour BI, IP - ABIN967762 : Aplin, Stewart, Assoian, Juliano: Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1. dans The Journal of cell biology 2001 (PubMed)
    Show all 5 references for 967762

  3. Human Polyclonal MAP2K1 Primary Antibody pour EIA, IHC (p) - ABIN358157 : Ohren, Chen, Pavlovsky, Whitehead, Zhang, Kuffa, Yan, McConnell, Spessard, Banotai, Mueller, Delaney, Omer, Sebolt-Leopold, Dudley, Leung, Flamme, Warmus, Kaufman, Barrett, Tecle, Hasemann: Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition. dans Nature structural & molecular biology 2004 (PubMed)
    Show all 5 references for 358157

  4. Human Polyclonal MAP2K1 Primary Antibody pour IHC (p), WB - ABIN1881525 : Zheng, Fiumara, Li, Georgakis, Snell, Younes, Vauthey, Carbone, Younes: MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival. dans Blood 2003 (PubMed)
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  5. Human Polyclonal MAP2K1 Primary Antibody pour EIA - ABIN358538 : Naegele, Morley: Molecular cross-talk between MEK1/2 and mTOR signaling during recovery of 293 cells from hypertonic stress. dans The Journal of biological chemistry 2004 (PubMed)
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  6. Human Monoclonal MAP2K1 Primary Antibody pour WB - ABIN967599 : Eblen, Slack, Weber, Catling: Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes. dans Molecular and cellular biology 2002 (PubMed)
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  7. Human Polyclonal MAP2K1 Primary Antibody pour IHC (p), WB - ABIN197388 : Zebisch, Staber, Delavar, Bodner, Hiden, Fischereder, Janakiraman, Linkesch, Auner, Emberger, Windpassinger, Schimek, Hoefler, Troppmair, Sill: Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia. dans Cancer research 2006 (PubMed)
    Show all 3 references for 197388

  8. Human Polyclonal MAP2K1 Primary Antibody pour WB - ABIN197066 : Burroughs, Oh, Barrett, DiAugustine et al.: Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible ... dans Molecular cancer research : MCR 2003 (PubMed)
    Show all 2 references for 197066

  9. Human Polyclonal MAP2K1 Primary Antibody pour IHC (p), WB - ABIN196944 : Shen, Ouyang, Qu, Alonso, Sperzel, Mustelin, Kaplan, Feng: Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction. dans Molecular and cellular biology 2002 (PubMed)
    Show all 2 references for 196944

Plus d’anticorps contre MAP2K1 partenaires d’interaction

Human Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. MEK1 is constitutively and mainly phosphorylated at the Thr (Montrer TRH Anticorps)-292, Ser (Montrer SIGLEC1 Anticorps)-298, Thr (Montrer TRH Anticorps)-386, and Thr (Montrer TRH Anticorps)-388 residues in vivo, and combinations of phosphorylations at these four residues produce at least six phosphorylated variants of MEK1. The phosphorylation statuses of Thr (Montrer TRH Anticorps)-292, Ser (Montrer SIGLEC1 Anticorps)-298, Thr (Montrer TRH Anticorps)-386, and Thr (Montrer TRH Anticorps)-388 residues vary widely during activation and deactivation of the MAPK (Montrer MAPK1 Anticorps) pathway.

  2. TNFRSF14 (Montrer TNFRSF14 Anticorps) and MAP2K1 mutations are the most frequent genetic alterations found in pediatric-type follicular lymphoma (PTFL) and occur independently in most cases, suggesting that both mutations might play an important role in PTFL lymphomagenesis.

  3. There was no statistically significant association between BRAF (Montrer BRAF Anticorps) or MAP2K1 mutation and anatomic site, unifocal versus multifocal presentation, or clinical outcome in Langerhans cell histiocytosis.

  4. High MEK1 expression is associated with inflammation.

  5. Lgr4 (Montrer LGR4 Anticorps) is a critical positive factor for skin tumorigenesis by mediating the activation of MEK1/ERK1/2 (Montrer MAPK1/3 Anticorps) and Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) pathways.

  6. somatic mutations in MAP2K1 are a common cause of extracranial arteriovenous malformation

  7. MEK1 mutation is associated with central nervous system metastases of non-small cell lung cancer.

  8. The MAP2K1 mutation analysis of three hairy cell leukemia cases, one hairy cell leukemia-variant case, and three splenic marginal zone lymphoma cases revealed negative results.

  9. Data show that mitogen-activated protein kinase (Montrer MAPK1 Anticorps) kinases MEK1/2 inhibitor pimasertib (MEKI) sensitized the cells to apoptosis through its ability to promote a G1 cell cycle arrest.

  10. the purpose of this paper was to investigate MAPK (Montrer MAPK1 Anticorps) downstream signalling molecules in Natural killer cell phenotypes from Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. Lgr4 (Montrer LGR4 Anticorps) is a critical positive factor for skin tumorigenesis by mediating the activation of MEK1/ERK1/2 (Montrer MAPK1/3 Anticorps) and Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) pathways.

  2. FGF2 (Montrer FGF2 Anticorps) is an extracellular inducer of COUP-TFII (Montrer NR2F2 Anticorps) expression and may suppress the osteogenic potential of mesenchymal cells by inducing COUP-TFII (Montrer NR2F2 Anticorps) expression prior to the onset of osteogenic differentiation

  3. REDD1 (Montrer DDIT4 Anticorps) is required for normal insulin (Montrer INS Anticorps)-stimulated signaling, and a subtle balance exists between MEK1/2, REDD1 (Montrer DDIT4 Anticorps), and mTOR (Montrer FRAP1 Anticorps)

  4. blood glucose levels are reduced by suppression of MEK1 expression in the liver of db/db (Montrer LEPR Anticorps) mice

  5. MEK1 and MEK2 (Montrer MAP2K2 Anticorps) can substitute for each other but a minimum amount of MEK (Montrer MDK Anticorps) is critical for placenta development and embryo survival

  6. Aberrant phosphorylation of AKT (Montrer AKT1 Anticorps) and MEK (Montrer MDK Anticorps) signalling pathways was identified in cells carrying mutant huntingtin (Montrer HTT Anticorps).

  7. An essential function for MEK1 in macrophages in regulating the ERK1/2 (Montrer MAPK1/3 Anticorps) and STAT4 (Montrer STAT4 Anticorps) pathways in response to TLR4 (Montrer TLR4 Anticorps) activation.

  8. Nuclear enrichment of MEK1 physically sequesters peroxisome proliferator-activated receptor gamma (PPARgamma (Montrer PPARG Anticorps)), inhibiting adipogenesis and disrupting ERK (Montrer EPHB2 Anticorps) signaling.

  9. MEK1 is inhibited by phosphorylation at Thr (Montrer TRH Anticorps)-292/286 by Cdk5 (Montrer CDK5 Anticorps), ERK (Montrer EPHB2 Anticorps), and Cdk1 (Montrer CDK1 Anticorps).

  10. The effect of Akt1 (Montrer AKT1 Anticorps) and Mek1 on extracellular matrix synthesis was reconciled through the activation of p70 S6-kinase (Montrer PRKACB Anticorps).

Xenopus laevis Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. in FGFR1 (Montrer FGFR1 Anticorps) signalling JNK1 (Montrer MAPK8 Anticorps) phosphorylation depends on ERK2 (Montrer MAPK1 Anticorps)

  2. The data demonstrate that ERK (Montrer MAPK1 Anticorps) phosphorylation of UBF prevents DNA bending by its first two HMG (Montrer SSRP1 Anticorps) boxes, leading to a cooperative unfolding of the enhancesome

  3. We propose that Erk2 MAP kinase (Montrer MAPK1 Anticorps) phosphorylation of Vg1RBP (Montrer IGF2BP3 Anticorps) regulates the protein:protein-mediated association of Vg1 mRNP with the cytoskeleton and/or ER.

Rabbit Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. Extracellular signal-regulated kinase (ERK (Montrer MAPK1 Anticorps)) pathway plays a role in dedifferentiation of rabbit articular chondrocytes.

  2. KSR (Montrer KSR1 Anticorps) interacts with a regulatory Raf (Montrer RAF1 Anticorps) molecule in cis (Montrer CISH Anticorps) to induce a conformational switch of MEK, facilitating MEK's phosphorylation by a separate catalytic Raf (Montrer RAF1 Anticorps) molecule in trans

Pig (Porcine) Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. Data indicate that MEKK2 (Montrer MAP3K2 Anticorps) is required for the mekk1 (Montrer MAP3K1 Anticorps), mkk1 mkk2 (Montrer MAP2K2 Anticorps), and mpk4 (Montrer MAPK4 Anticorps) autoimmune phenotypes.

  2. Data suggest that the MEKK1 (Montrer MAP3K1 Anticorps)-MKK1/MKK2 (Montrer MAP2K2 Anticorps)-MPK4 (Montrer MAPK4 Anticorps) kinase cascade negatively regulates MEKK2 (Montrer MAP3K2 Anticorps) and activation of MEKK2 (Montrer MAP3K2 Anticorps) triggers SUMM2-mediated immune responses.

  3. miR (Montrer MYLIP Anticorps)-1826 plays an important role as tumor suppressor via CTNNB1 (Montrer CTNNB1 Anticorps)/MEK1/VEGFC (Montrer VEGFC Anticorps) downregulation in bladder cancer.

  4. ETS1 (Montrer ETS1 Anticorps) is probably mediating high CIP2A (Montrer KIAA1524 Anticorps) expression in human cancers with increased EGFR (Montrer EGFR Anticorps)-MEK1/2-ERK (Montrer MAPK1 Anticorps) pathway activity

  5. An analysis of the interation of MEKK1 (Montrer MAP3K1 Anticorps) and MEK1 in response to wounding stress in A. thaliana seedlings is presented.

  6. This study demonstrated that the MKK1 signalling pathway modulates the expression of genes responding to elicitors and plays an important role in pathogen defence.

  7. These results suggest that the formation of SUMO-1 (Montrer SUMO1 Anticorps) foci is regulated by the MEK-ERK (Montrer MAPK1 Anticorps) pathway and may induce apoptosis.

  8. AtMEK1 is a crucial mediator in plant stress signal transduction.

  9. double loss-of-function mutant (mkk1/2) of MKK1 and MKK2 (Montrer MAP2K2 Anticorps) is shown to have marked phenotypes in development and disease resistance similar to those of the single mekk1 (Montrer MAP3K1 Anticorps) and mpk4 (Montrer MAPK4 Anticorps) mutants

  10. Activation of MPK4 (Montrer MAPK4 Anticorps) by flg22 is impaired in the mkk1 mkk2 (Montrer MAP2K2 Anticorps) double mutants, suggesting that MKK1 and MKK2 (Montrer MAP2K2 Anticorps) function together with MPK4 (Montrer MAPK4 Anticorps) and MEKK1 (Montrer MAP3K1 Anticorps) in a MAP kinase (Montrer MAPK1 Anticorps) cascade to negatively regulate innate immune responses in plants.

MAP2K1 profil antigène

Antigen Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Alternative names and synonyms associated with MAP2K1

  • mitogen activated protein kinase kinase 1 (Map2k1) anticorps
  • mitogen-activated protein kinase kinase 1 (MAP2K1) anticorps
  • mitogen-activated protein kinase kinase 1 (Map2k1) anticorps
  • mitogen-activated protein kinase kinase 1 (map2k1) anticorps
  • mitogen-activated protein kinase kinase 1 (MEK1) anticorps
  • ATMEK1 anticorps
  • CFC3 anticorps
  • F20B18.180 anticorps
  • F20B18_180 anticorps
  • MAP kinase/ ERK kinase 1 anticorps
  • MAPKK1 anticorps
  • MEK anticorps
  • mek-2 anticorps
  • MEK1 anticorps
  • MEKK1 anticorps
  • MITOGEN ACTIVATED PROTEIN KINASE KINASE anticorps
  • MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 anticorps
  • MKK1 anticorps
  • NMAPKK anticorps
  • Prkmk1 anticorps
  • si:ch211-242m18.2 anticorps
  • wu:fj56a12 anticorps
  • wu:fj61b01 anticorps
  • zgc:56557 anticorps

Protein level used designations for MAP2K1

ERK activator kinase 1 , MAP kinase kinase 1 , MAP kinase/Erk kinase 1 , MAPK/ERK kinase 1 , MAPKK 1 , dual specificity mitogen-activated protein kinase kinase 1 , mitogen-activated protein kinase kinase 1 , MEK 1 , protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1) , dual specificity mitogen activated protein kinase kinase 1 , mitogen activated protein kinase kinase 1 , protein kinase, mitogen activated, kinase 1, p45 , MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2) , MEK1

GENE ID SPECIES
170851 Rattus norvegicus
5604 Homo sapiens
478347 Canis lupus familiaris
26395 Mus musculus
379991 Xenopus laevis
415549 Gallus gallus
533199 Bos taurus
406728 Danio rerio
100009316 Oryctolagus cuniculus
100233191 Sus scrofa
828713 Arabidopsis thaliana
450188 Pan troglodytes
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