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Aperçu des produits pour anti-MAP2K2 (MAP2K2) Anticorps

Full name:
anti-Mitogen-Activated Protein Kinase Kinase 2 Anticorps (MAP2K2)
Chez www.anticorps-enligne.fr sont 265 Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) Anticorps de 29 de différents fournisseurs disponibles. De plus, nous expédions MAP2K2 Protéines (19) et MAP2K2 Kits (10) et beaucoup plus de produits pour cette protéine. Un total de 311 MAP2K2 produits sont actuellement listés.
Synonymes:
AA589381, ATMKK2, CFC4, F27B13.50, F27B13_50, MAP KINASE KINASE 1, MAP kinase kinase 2, MAPKK2, MEK2, MK1, MK2, MKK2, PRKMK2

Réactivités les plus populaires pour anti-MAP2K2 (MAP2K2) Anticorps

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anti-MAP2K2 Anticorps mieux référencés

  1. Human Polyclonal MAP2K2 Primary Antibody pour IHC (p), WB - ABIN1881526 : Burroughs, Oh, Barrett, DiAugustine et al.: Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible ... dans Molecular cancer research : MCR 2003 (PubMed)
    Show all 5 references for ABIN1881526

  2. Chicken Monoclonal MAP2K2 Primary Antibody pour IHC (f), IF - ABIN967845 : Crews, Alessandrini, Erikson: The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. dans Science (New York, N.Y.) 1992 (PubMed)
    Show all 5 references for ABIN967845

  3. Human Polyclonal MAP2K2 Primary Antibody pour IHC (p), WB - ABIN197106 : Alessi, Saito, Campbell, Cohen, Sithanandam, Rapp, Ashworth, Marshall, Cowley: Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1. dans The EMBO journal 1994 (PubMed)
    Show all 2 references for ABIN197106

  4. Human Polyclonal MAP2K2 Primary Antibody pour IHC, ELISA - ABIN1531905 : Rosen, Ginty, Weber, Greenberg: Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. dans Neuron 1994 (PubMed)
    Show all 2 references for ABIN1531905

  5. Human Polyclonal MAP2K2 Primary Antibody pour EIA, IHC (p) - ABIN360373 : Tran, Maurer, Nagamine: Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2. dans Molecular and cellular biology 2003 (PubMed)
    Show all 2 references for ABIN360373

  6. Chicken Polyclonal MAP2K2 Primary Antibody pour IHC, WB - ABIN2783573 : Adjei, Cohen, Franklin, Morris, Wilson, Molina, Hanson, Gore, Chow, Leong, Maloney, Gordon, Simmons, Marlow, Litwiler, Brown, Poch, Kane, Haney, Eckhardt: Phase I pharmacokinetic and pharmacodynamic study of the oral, small-molecule mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) in patients with advanced cancers. dans Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 (PubMed)

Plus d’anticorps contre MAP2K2 partenaires d’interaction

Human Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) interaction partners

  1. The patient showed a paternally inherited 16p13.11 microduplication and a de novo 19p13.3 microdeletion involving the mitogen-activated protein kinase kinase 2 gene (MAP2K2), in which mutations cause the cardio-facio-cutaneous (CFC (Montrer PTPN11 Anticorps)) syndrome

  2. Data show that mitogen-activated protein kinase (Montrer MAPK1 Anticorps) kinases MEK1 (Montrer MAP2K1 Anticorps)/2 inhibitor pimasertib (MEKI) sensitized the cells to apoptosis through its ability to promote a G1 cell cycle arrest.

  3. the purpose of this paper was to investigate MAPK (Montrer MAPK1 Anticorps) downstream signalling molecules in Natural killer cell phenotypes from Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients.

  4. at clinically relevant concentrations, cDDP binds to and inhibits MEK1 (Montrer MAP2K1 Anticorps)/2 and both the binding and inhibitory activity are related to its interaction with Cu bound to MEK1 (Montrer MAP2K1 Anticorps)/2

  5. Endocytosis separates EGF (Montrer EGF Anticorps) receptors from endogenous fluorescently labeled HRas (Montrer HRAS Anticorps) and diminishes receptor signaling to MAP kinases in endosomes.

  6. MEK1 (Montrer MAP2K1 Anticorps) levels are upregulated at transcriptional level whereas MEK2 levels are downregulated at posttranslational level.

  7. MEK1/2 inhibitor trametinib showed similar PFS and a response rate as docetaxel in patients with previously treated KRAS-mutant-positive non-small cell lung carcinoma.

  8. We report on a fourth familial case with transmission of CFC (Montrer PTPN11 Anticorps) syndrome from father to son due to a novel heterozygous sequence change c.376A>G (p.N126D) in exon 3 of MEK2 gene.

  9. MK2 (Montrer KCNA2 Anticorps) attenuates dendritic cell-mediated Th1 (Montrer TH1L Anticorps) differentiation and autoimmune encephalomyelitis.

  10. We documented three novel mutations in the BRAF (Montrer BRAF Anticorps) gene in cardio-facio-cutaneous syndrome patients and correlated clinical findings with causative mutations in the BRAF (Montrer BRAF Anticorps) or MEK1 (Montrer MAP2K1 Anticorps)/MEK2 genes

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) interaction partners

  1. MEK1 (Montrer MAP2K1 Anticorps) and MEK2 can substitute for each other but a minimum amount of MEK (Montrer MDK Anticorps) is critical for placenta development and embryo survival

  2. MK2 (Montrer KCNA2 Anticorps)/3 cascade plays a strategic role in controlling synaptic plasticity and cognition.

  3. MK2 (Montrer KCNA2 Anticorps) attenuates dendritic cell-mediated Th1 (Montrer HAND1 Anticorps) differentiation and autoimmune encephalomyelitis.

  4. analysis of p38 (Montrer CRK Anticorps)-MK2 (Montrer KCNA2 Anticorps)-activated Rsk (Montrer RPS6KA1 Anticorps) signaling in toll (Montrer TLR4 Anticorps)-like receptor-stimulated dendritic cells

  5. both MEK1 (Montrer MAP2K1 Anticorps) and MEK2 have crucial roles in the integration of mesenchymal and epithelial signals essential for the development of the entire respiratory tract

  6. MK2 (Montrer KCNA2 Anticorps) is responsible for resistance of p53 (Montrer TP53 Anticorps)-deficient tumors to cisplatin

  7. MK2 (Montrer KCNA2 Anticorps) plays a critical role in the development of apoptosis.

  8. rapamycin treatment led to an increased MKP1 (Montrer DUSP1 Anticorps) expression in BMDM from WT but failed to do so in BMDMs lacking the AKT1 (Montrer AKT1 Anticorps) isoform or MEK1 (Montrer MAP2K1 Anticorps) and MEK2.

  9. review focuses on the role of the MEK1 (Montrer MAP2K1 Anticorps) and MEK2 kinases in the development of extraembryonic tissues and in the formation of the placenta

  10. AT(2)R-mediated eNOS (Montrer NOS3 Anticorps) NO production and vasorelaxation through a MEK (Montrer MDK Anticorps) pathway are enhanced in aortas from db/db (Montrer LEPR Anticorps) mice.

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) interaction partners

  1. the AtMKK2-AtMPK10 (Montrer MAPK10 Anticorps) MAPK (Montrer MAPK1 Anticorps) module regulates leaf venation complexity by altering polar auxin transport efficiency

  2. Treatment of Arabidopsis with a membrane rigidifier, DMSO, causes MPK4 (Montrer MAPK4 Anticorps) activation concomitantly with MEKK1 (Montrer MAP3K1 Anticorps) and MKK2 phosphorylation.

  3. Ca(2 (Montrer CA2 Anticorps)+) signaling occurred upstream of the MEKK1 (Montrer MAP3K1 Anticorps)-MKK2 pathway. MEKK1 (Montrer MAP3K1 Anticorps) was phosphorylated by calcium/calmodulin (Montrer CALM Anticorps)-regulated receptor-like kinase (CRLK1), which suggested that CRLK1 is one of candidates located upstream of MEKK1 (Montrer MAP3K1 Anticorps).

  4. Data indicate that MEKK2 (Montrer MAP3K2 Anticorps) is required for the mekk1 (Montrer MAP3K1 Anticorps), mkk1 (Montrer MAP2K1 Anticorps) mkk2, and mpk4 (Montrer MAPK4 Anticorps) autoimmune phenotypes.

  5. Data suggest that the MEKK1 (Montrer MAP3K1 Anticorps)-MKK1 (Montrer MAP2K1 Anticorps)/MKK2-MPK4 (Montrer MAPK4 Anticorps) kinase cascade negatively regulates MEKK2 (Montrer MAP3K2 Anticorps) and activation of MEKK2 (Montrer MAP3K2 Anticorps) triggers SUMM2-mediated immune responses.

  6. Data indicate that MKK2 plays a role in abiotic stress tolerance and plant disease resistance.

  7. double loss-of-function mutant (mkk1 (Montrer MAP2K1 Anticorps)/2) of MKK1 (Montrer MAP2K1 Anticorps) and MKK2 is shown to have marked phenotypes in development and disease

  8. Activation of MPK4 (Montrer MAPK4 Anticorps) by flg22 is impaired in the mkk1 (Montrer MAP2K1 Anticorps) mkk2 double mutants, suggesting that MKK1 (Montrer MAP2K1 Anticorps) and MKK2 function together with MPK4 (Montrer MAPK4 Anticorps) and MEKK1 (Montrer MAP3K1 Anticorps) in a MAP kinase (Montrer MAPK1 Anticorps) cascade to negatively regulate innate immune responses in plants.

MAP2K2 profil antigène

Antigen Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.

Alternative names and synonyms associated with MAP2K2

  • mitogen activated protein kinase kinase 2 (Map2k2) anticorps
  • mitogen-activated protein kinase kinase 2 (MAP2K2) anticorps
  • mitogen-activated protein kinase kinase 2 (Map2k2) anticorps
  • mitogen-activated protein kinase kinase 2 (MKK2) anticorps
  • AA589381 anticorps
  • ATMKK2 anticorps
  • CFC4 anticorps
  • F27B13.50 anticorps
  • F27B13_50 anticorps
  • MAP KINASE KINASE 1 anticorps
  • MAP kinase kinase 2 anticorps
  • MAPKK2 anticorps
  • MEK2 anticorps
  • MK1 anticorps
  • MK2 anticorps
  • MKK2 anticorps
  • PRKMK2 anticorps

Protein level used designations for MAP2K2

ERK activator kinase 2 , MAP kinase kinase 2 , MAPK/ERK kinase 2 , MAPKK 2 , MEK 2 , MEK2 , dual specificity mitogen-activated protein kinase kinase 2 , mitogen-activated protein kinase kinase 2, p45 , MAP kinase/Erk kinase , mitogen activated protein kinase kinase 2 , protein kinase, mitogen activated, kinase 2, p45 , dual specificity mitogen activated protein kinase kinase 2 , mitogen-activated protein kinase kinase type 2

GENE ID SPECIES
58960 Rattus norvegicus
5605 Homo sapiens
26396 Mus musculus
611939 Canis lupus familiaris
396349 Gallus gallus
510434 Bos taurus
829103 Arabidopsis thaliana
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