Aperçu des produits pour anti-MAP3K11 (MAP3K11) Anticorps

Full name:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 Anticorps (MAP3K11)
Chez www.anticorps-enligne.fr sont 60 Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) Anticorps de 17 de différents fournisseurs disponibles. De plus, nous expédions MAP3K11 Protéines (6) et beaucoup plus de produits pour cette protéine. Un total de 70 MAP3K11 produits sont actuellement listés.
Synonymes:
2610017K16Rik, MEKK11, Mlk-3, Mlk3, PTK1, RHOE, SPRK

Réactivités les plus populaires pour anti-MAP3K11 (MAP3K11) Anticorps

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anti-Human MAP3K11 Anticorps:

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anti-MAP3K11 Anticorps mieux référencés

  1. Human Monoclonal MAP3K11 Primary Antibody pour WB - ABIN659128 : Chen, Miller, Gallo: MLK3 is critical for breast cancer cell migration and promotes a malignant phenotype in mammary epithelial cells. dans Oncogene 2010 (PubMed)
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  2. Human Polyclonal MAP3K11 Primary Antibody pour WB - ABIN651367 : Rangasamy, Mishra, Mehrotra, Sondarva, Ray, Rao, Chatterjee, Rana, Rana: Estrogen suppresses MLK3-mediated apoptosis sensitivity in ER+ breast cancer cells. dans Cancer research 2010 (PubMed)
    Show all 3 references for 651367

  3. Cow (Bovine) Polyclonal MAP3K11 Primary Antibody pour WB - ABIN2786655 : Muniyappa, Das: Activation of c-Jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: a MLK-3-MKK7-dependent mechanism. dans Cellular signalling 2008 (PubMed)

  4. Human Polyclonal MAP3K11 Primary Antibody pour WB - ABIN4334888 : Chien, Lin, Wang, Lee, Chen, Fong, Shih: Acacetin inhibits the invasion and migration of human non-small cell lung cancer A549 cells by suppressing the p38α MAPK signaling pathway. dans Molecular and cellular biochemistry 2011 (PubMed)

  5. Human Polyclonal MAP3K11 Primary Antibody pour IHC, ELISA - ABIN1533179 : Ing, Leung, Heng, Tsui, Lassam: MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain. dans Oncogene 1994 (PubMed)

Plus d’anticorps contre MAP3K11 partenaires d’interaction

Human Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) interaction partners

  1. Data indicate that BTG2 (Montrer BTG2 Anticorps), MAP3K11, RPS6KA1 (Montrer RPS6KA1 Anticorps) and PRDM1 (Montrer PRDM1 Anticorps) as putative targets of microRNA miR (Montrer MLXIP Anticorps)-125b.

  2. Increased expression of MAP3K11 is associated with esophageal cancer.

  3. During hepatocyte lipotoxicity, activated MLK3 induces the release of CXCL10 (Montrer CXCL10 Anticorps)-bearing vesicles from hepatocytes, which are chemotactic for macrophages.

  4. MLK3 serves as a common upstream kinase of AMPK (Montrer PRKAA1 Anticorps) and JNK (Montrer MAPK8 Anticorps) and functions as a direct upstream kinase for AMPK (Montrer PRKAA1 Anticorps) independent of LKB1 (Montrer STK11 Anticorps)

  5. MLK3 represents a newly recognized integral component of HER2 (Montrer ERBB2 Anticorps) biology in HER2 (Montrer ERBB2 Anticorps)+ breast tumors.

  6. MLK3 is a critical factor controlling the activity of kinase networks that control the cellular responses to different concentrations of reactive oxygen species.

  7. Signaling pathways associated with the Pro252His mutation in MLK3 are located in the kinase domain which is an important domain for the regulation of downstream signaling pathways.

  8. CHIP modulates MLK3 protein levels in response to Geldanamycin and stress stimuli, and CHIP-dependent regulation of MLK3 is required for suppression of SKOV3 ovarian cancer cell invasion.

  9. Data indicate URMC-099 as an orally bioavailable, potent mixed lineage kinase 3 MLK3 inhibitor.

  10. CTGF acting through Rac1 activates the MLK3/JNK signaling pathway, which in turn initiates AP-1 activation and recruitment of c-Jun and c-Fos to the collagen I promoter and ultimately induces collagen I expression in human lung fibroblasts

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) interaction partners

  1. MAP3K11 might function as an important tumor suppressor neutralized by oncomiR-125b in B-cell leukemia.

  2. During hepatocyte lipotoxicity, activated MLK3 (Montrer KCNK7 Anticorps) induces the release of CXCL10 (Montrer CXCL10 Anticorps)-bearing vesicles from hepatocytes, which are chemotactic for macrophages.

  3. TRB3 (Montrer TRIB3 Anticorps)(-/-) islets show a decrease in both the amplitude and duration of cytokine-stimulated MLK3 (Montrer KCNK7 Anticorps) induction and JNK (Montrer MAPK8 Anticorps) activation.

  4. MLK3 (Montrer KCNK7 Anticorps) limits RhoA (Montrer RHOA Anticorps) activation and injury-induced neointima formation by binding to and inhibiting the activation of p63Rho guanine nucleotide exchange factor (Montrer ARHGEF12 Anticorps), a RhoA (Montrer RHOA Anticorps) activator.

  5. Genetic or pharmacologic inhibition of MLK3 (Montrer KCNK7 Anticorps) blocks fMLP (Montrer FPR1 Anticorps)-mediated motility of neutrophils both in vitro and in vivo, suggesting that MLK3 (Montrer KCNK7 Anticorps) may be a therapeutic target in human diseases characterized by exuberant neutrophil migration.

  6. Data indicate URMC-099 as an orally bioavailable, potent mixed lineage kinase 3 MLK3 inhibitor.

  7. Data from knockout mice suggest that MLK3 (Montrer KCNK7 Anticorps) plays role in saturated fatty acid-induced activation of MAP kinase (Montrer MAPK1 Anticorps) signaling; MLK3 (Montrer KCNK7 Anticorps) appears to be involved in pathogenesis of obesity, adipose tissue in fl ammation, insulin (Montrer INS Anticorps) resistance, and fatty liver disease.

  8. Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 (Montrer MAPK8IP1 Anticorps) scaffold protein (Montrer HOMER1 Anticorps) in cytokine-induced pancreatic beta cell death

  9. These results reveal a novel role for MLK3 (Montrer KCNK7 Anticorps) signaling in the regulation of intestinal epithelial migration in vivo and suggest that MLK3 (Montrer KCNK7 Anticorps) may be an important target for the regulation of intestinal mucosal healing.

  10. mice with a targeted deletion of Mlk3 (Montrer KCNK7 Anticorps) displayed multiple skeletal defects, including dental abnormalities, deficient calvarial mineralization, and reduced bone mass

MAP3K11 profil antigène

Antigen Summary

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.

Alternative names and synonyms associated with MAP3K11

  • mitogen-activated protein kinase kinase kinase 11 (MAP3K11) anticorps
  • mitogen-activated protein kinase kinase kinase 11 (Map3k11) anticorps
  • 2610017K16Rik anticorps
  • MEKK11 anticorps
  • Mlk-3 anticorps
  • Mlk3 anticorps
  • PTK1 anticorps
  • RHOE anticorps
  • SPRK anticorps

Protein level used designations for MAP3K11

SH3 domain-containing proline-rich kinase , mixed lineage kinase 3 , protein-tyrosine kinase PTK1 , src-homology 3 domain-containing proline-rich kinase , mitogen activated protein kinase kinase kinase 11

GENE ID SPECIES
4296 Homo sapiens
26403 Mus musculus
309168 Rattus norvegicus
483732 Canis lupus familiaris
514210 Bos taurus
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