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anti-Human MAPK12 Anticorps:
anti-Mouse (Murine) MAPK12 Anticorps:
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Cow (Bovine) Polyclonal MAPK12 Primary Antibody pour WB - ABIN611036
Fulda, Meyer, Debatin: Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression. dans Oncogene 2002
Show all 3 Pubmed References
Human Polyclonal MAPK12 Primary Antibody pour PLA, WB - ABIN520005
Liu, Chen, Chau, Jan, Chen, Hsu, Lin, Juang, Lu, Cheng, Chen, Chang, Ting, Kao, Hsiao, Huang: Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma. dans Molecular & cellular proteomics : MCP 2013
Study propose a model for sequential roles of MPK12, HT1, and GHR1 in the ABA-independent regulation of SLAC1 during CO2-induced stomatal closure.
MPK9 (Montrer MAPK9 Anticorps) and MPK12 are positive regulators of salicylic acid signaling in Arabidopsis guard cells.
MPK9 (Montrer MAPK9 Anticorps) and MPK12 are key regulators mediating both abscisic acid (ABA) and Methyl jasmonate (MeJA) signalling in guard cells.
MPK9 (Montrer MAPK9 Anticorps) and MPK12 function redundantly downstream of extracellular reactive oxygen production and intracellular accumulation, cytosolic alkalisation and Ca(2 (Montrer CA2 Anticorps)+)cytosolic oscillation in yeast elcictor-induced stomatal closure
MPK9 (Montrer MAPK9 Anticorps) and MPK12 act downstream of ROS (Montrer ROS1 Anticorps) and cytosolic Ca2 (Montrer CA2 Anticorps)+ and upstream of anion channels in the guard cell abscisic acid signaling cascade.
MAP kinases MPK9 (Montrer MAPK9 Anticorps) and MPK12 are preferentially expressed in guard cells and positively regulate ROS (Montrer ROS1 Anticorps)-mediated ABA signaling.
MPK12 is both a physiological substrate of IBR5 and a novel negative regulator of auxin signaling.
There was significant association between p38gamma expression and esophageal squamous cell carcinoma clinical stage, lymph nodes metastases, and tumor volume. p38delta (Montrer MAPK1/3 Anticorps) overexpression can promote tumorigenesis in nude mice model xenografted with Eca109 cells whose basal level of p38delta (Montrer MAPK1/3 Anticorps) was stably over-expressed and p38gamma was stably knocked down.
This study reveals a novel pathway that directly links ErbB4 (Montrer ERBB4 Anticorps) and p38gamma to the transcriptional machinery of NKx2.5 (Montrer NKX2-5 Anticorps)-GATA4 (Montrer GATA4 Anticorps) complex which is critical for cardiomyocyte formation during mammalian heart development.
during interphase ERK3 (Montrer MAPK4 Anticorps) is mainly resident in the nucleoplasm in association with ribonuclear proteins involved in early pre-mRNA splicing, it undergoes cell cycle-dependent redistribution and, during apoptosis
Taken together our data suggest that as cells initiate adhesion to matrix increasing levels of ERK3 (Montrer MAPK4 Anticorps) at the cell periphery are required to orchestrate cell morphology changes which can then drive migratory behavior.
p38gamma and p38delta (Montrer MAPK1/3 Anticorps) reprogram liver metabolism by modulating neutrophil infiltration and provide a potential target for NAFLD (Montrer TSC2 Anticorps) therapy
analysis of how allosteric regulation of p38gamma and PTPN3 (Montrer PTPN3 Anticorps) involves a PDZ domain (Montrer INADL Anticorps)-modulated complex formation
Thus, in endothelial cells p38alpha (Montrer MAPK14 Anticorps) mediates apoptotic signaling, whereas p38beta (Montrer MAPK11 Anticorps) and p38gamma transduce survival signaling
p38gamma Mitogen-activated protein kinase signals through phosphorylating its phosphatase PTPH1 in regulating ras protein oncogenesis and stress response.
SEPW1 (Montrer SEPW1 Anticorps) silencing increases MKK4 (Montrer MAP2K4 Anticorps), which activates p38gamma, p38delta (Montrer MAPK1/3 Anticorps), and JNK2 (Montrer MAPK9 Anticorps) to phosphorylate p53 (Montrer TP53 Anticorps) on Ser (Montrer SIGLEC1 Anticorps)-33 and cause a transient G(1) arrest.
phosphorylation at Ser (Montrer SIGLEC1 Anticorps)-118 is required for ER to bind both p38gamma and c-Jun (Montrer JUN Anticorps), thereby promoting ER relocation from ERE to AP-1 (Montrer FOSB Anticorps) promoter sites.
p38gamma mitogen-activated protein kinase (Montrer MAPK1 Anticorps) mediates inflammatory signaling to promote colon tumorigenesis
p38gamma and p38delta (Montrer MAPK1/3 Anticorps) control heart growth by modulating mTOR (Montrer FRAP1 Anticorps) pathway through DEPTOR (Montrer DEPTOR Anticorps) phosphorylation and subsequent degradation.
Findings provide genetic evidence that p38gamma and p38delta (Montrer MAPK1/3 Anticorps) have essential roles in skin tumour development.
Together, our results establish that p38gamma and p38delta (Montrer MAPK1/3 Anticorps) are central to colitis-associated colon cancer formation through regulation of hematopoietic cell response to injury, and validate p38gamma and p38kappa as potential targets for cancer therapy.
An energetic signal may trigger phosphorylation of the p38-gamma isoform which may explain how contractions differentially activate signaling pathways.
p38gamma and p38delta (Montrer MAPK1/3 Anticorps) are crucial regulators of inflammatory joint destruction in collagen-induced arthritis.
p38gamma and p38delta (Montrer MAPK1/3 Anticorps) kinases regulate the Toll-like receptor 4 (TLR4 (Montrer TLR4 Anticorps))-induced cytokine production by controlling ERK1/2 (Montrer MAPK1/3 Anticorps) protein kinase (Montrer CDK7 Anticorps) pathway activation
results indicate that p38gamma and p38delta (Montrer MAPK1/3 Anticorps) have a role in the suppression of tumor development
Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.
mitogen-activated protein kinase 12
, MAP kinase 12
, MAPK 12
, extracellular signal-regulated kinase 6
, stress-activated protein kinase 3
, MAP kinase p38 gamma
, mitogen-activated protein kinase 3
, mitogen-activated protein kinase p38 gamma
, mitogen activated protein kinase 12
, stress activated protein kinase 3
, SAP kinase-3