anti-Boeuf (Vache) MAPK14 anticorps pour Immunoprecipitation

Recommended MAPK14 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Mitogen-Activated Protein Kinase 14 (MAPK14) Anticorps
  • AP22.98
  • AP22_98
  • ATMPK14
  • mitogen-activated protein kinase 14
  • 186F5S
  • BG:DS00797.3
  • CG7393
  • D-p38
  • D-p38 MAPK
  • D-p38b
  • Dm p38b
  • Dmel\\CG7393
  • Dmp38b
  • Dp38
  • Dp38b
  • ESTS:186F5S
  • Mpk34C
  • anon-sts23
  • dp38b
  • p38
  • p38 MAPK
  • p38 beta
  • p38B
  • p38Kb
  • p38beta
  • CSBP
  • CSBP1
  • CSBP2
  • CSPB1
  • EXIP
  • Mxi2
  • PRKM14
  • PRKM15
  • RK
  • SAPK2A
  • p38ALPHA
  • Crk1
  • Csbp1
  • p38-alpha
  • p38MAPK
  • p38a
  • p38alpha
  • SAPK2a
  • CRK1
  • Csbp2
  • Exip
  • Hog
  • Prkm14
  • Prkm15
  • Sapk2A
  • p38Hog
  • csbp
  • mapk14a
  • mxi2
  • sapk2
  • sapk2a
  • mitogen-activated protein kinase 14
  • CG7393 gene product from transcript CG7393-RA
  • mitogen activated protein kinase 14
  • MPK14
  • MAPK14
  • Mapk14
  • p38b
  • mapk14
Épitope
AA 341-360
51
43
24
17
16
10
10
9
9
9
8
8
8
8
7
5
5
5
4
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Poulet, Boeuf (Vache), Chien, Cobaye, Hamster, Humain, Singe, Souris, Porc, Lapin, Rat (Rattus), Mouton
298
135
128
25
16
15
12
10
10
9
7
4
4
4
3
3
3
2
1
1
1
Hôte
Lapin
240
60
2
2
Clonalité
Polyclonal
Conjugué
Cet anticorp MAPK14 est non-conjugé
12
9
9
9
9
7
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
277
126
74
56
38
38
13
9
9
7
6
2
2
1
1
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N° du produit ABIN5551337
$ 375.38
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN1911926 IP WB Rabbit IgG AA 300-360, C-Term Connectez-vous pour afficher Polyclonal
1 ABIN1911924 IP WB Rabbit IgG AA 1-50 Connectez-vous pour afficher Polyclonal
1 ABIN307668 IP ELISA WB Rabbit AA 347-360 Connectez-vous pour afficher Polyclonal
1 ABIN1102944 IP IHC WB Rabbit Connectez-vous pour afficher Polyclonal
1 ABIN302107 IP WB Rabbit AA 341-360 Connectez-vous pour afficher Polyclonal

General

Antigène Mitogen-Activated Protein Kinase 14 (MAPK14) Anticorps
Épitope AA 341-360
(51), (43), (24), (17), (16), (10), (10), (9), (9), (9), (8), (8), (8), (8), (7), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Poulet, Boeuf (Vache), Chien, Cobaye, Hamster, Humain, Singe, Souris, Porc, Lapin, Rat (Rattus), Mouton
(298), (135), (128), (25), (16), (15), (12), (10), (10), (9), (7), (4), (4), (4), (3), (3), (3), (2), (1), (1), (1)
Hôte Lapin
(240), (60), (2), (2)
Clonalité
Polyclonal
Conjugué Cet anticorp MAPK14 est non-conjugé
(12), (9), (9), (9), (9), (7), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
(277), (126), (74), (56), (38), (38), (13), (9), (9), (7), (6), (2), (2), (1), (1)
Fournisseur Connectez-vous pour afficher

Détail du produit anti-MAPK14 anticorps

Détail du antigène MAPK14 Information d'application Stockage Images
Specificité Detects ~43 kDa corresponding to the molecular mass of p38 on SDS-PAGE immunoblots.
Purification Serum
Immunogène A 20 residue synthetic peptide based on the Human p38 (residues 341-360) with the Cysteine residue added and coupled to KLH
Isotype IgG

Détail du antigène MAPK14

Détail du produit anti-MAPK14 anticorps Information d'application Stockage Images Haut de la page
Antigène
Autre désignation MAP Kinase p38 alpha / MAPK14 (MAPK14 Antibody Extrait)
Sujet The MAPK (mitogen activated protein kinase) comprises a family of ubiquitous praline-directed, protein-serine/threonine kinases which signal transduction pathways that control intracellular events including acute responses to hormones and major developmental changes in organisms (1). This super family consists of stress activated protein kinases (SAPKs), extracellular signal-regulated kinases (ERKs), and p38 kinases, each of which forms a separate pathway (2). The kinase members that populate each pathway are sequentially activated by phosphorylation. Upon activation, p38 MAPK/SAPK2α translocates into the nucleus where it phosphorylates one or more nuclear substrates, effecting transcriptional changes and other cellular processes involved in cell growth, division, differentiation, inflammation, and death (3). Specifically p38 always acts as a pro-apoptotic factor with its activation leading to the release of cytochrome c from mitochondria and cleavage of caspase 3 and its downstream effector, PARP (4). p38 MAPK is activated by a variety of chemical stress inducers including hydrogen peroxide, heavy metals, anisomycin, sodium salicylate, LPS, and biological stress signals such as tumor necrosis factor, interleukin-1, ionizing and UV irradiation, hyperosmotic stress and chemotherapeutic drugs (5). As a result, p38 alpha has been widely validated as a target for inflammatory disease including rheumatoid arthritis, COPD and psoriasis (6) and has also been implicated in cancer, CNS and diabetes (7).Synonyms: CSBP, CSBP1, CSBP2, CSPB1, Cytokine suppressive anti-inflammatory drug-binding protein, MAX-interacting protein 2, MXI2, Mitogen-activated protein kinase 14, SAPK2A, p38 alpha
ID gène 1432
NCBI Accession NP_001306
UniProt Q16539
Domaine de recherche Kinases/Phosphatases
Pathways Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling

Information d'application

Détail du produit anti-MAPK14 anticorps Détail du antigène MAPK14 Stockage Images Haut de la page
Indications d'application Western blot: A 1/5000 dilution of this antibody was sufficient for detection of p38 in 20 μgof HeLa cell lysate by ECL Immunoblot analysis. Immunoprecipitation: 1/250. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-MAPK14 anticorps Détail du antigène MAPK14 Information d'application Images Haut de la page
Format Liquid
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.