anti-Souris PAK2 anticorps pour Enzyme Immunoassay

Recommended PAK2 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
P21-Activated Kinase 2 (PAK2) Anticorps
  • pak2
  • cb422
  • kinase
  • zgc:91798
  • wu:fb71h01
  • si:dz198m22.1
  • pak65
  • pakgamma
  • PAK65
  • PAKgamma
  • 5330420P17Rik
  • A130002K10Rik
  • AI836325
  • D16Ertd269e
  • PAK-2
  • mKIAA4182
  • gamma-PAK
  • PAKI
  • Pak3
  • p21 (CDKN1A)-activated kinase 2a
  • p21 protein (Cdc42/Rac)-activated kinase 2
  • pak2a
  • pak2
  • PAK2
  • Pak2
Épitope
C-Term
42
20
12
11
6
5
5
4
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
185
96
91
12
8
1
Hôte
Lapin
166
19
Clonalité
Polyclonal
Conjugué
Cet anticorp PAK2 est non-conjugé
4
4
4
4
4
4
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
166
101
76
35
19
6
6
4
2
2
2
1
Fournisseur
Connectez-vous pour afficher
Supplier Product No.
Connectez-vous pour afficher
Request

Recevoir ce produit gratuitement

Envoyez-nous votre proposition de validation. J'aimerais valider ce produit

Savoir plus

N° du produit ABIN5555094
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN5555095 EIA IHC (p) WB Rabbit IgG N-Term Connectez-vous pour afficher Polyclonal

General

Antigène P21-Activated Kinase 2 (PAK2) Anticorps
Épitope C-Term
(42), (20), (12), (11), (6), (5), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(185), (96), (91), (12), (8), (1)
Hôte Lapin
(166), (19)
Clonalité
Polyclonal
Conjugué Cet anticorp PAK2 est non-conjugé
(4), (4), (4), (4), (4), (4)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(166), (101), (76), (35), (19), (6), (6), (4), (2), (2), (2), (1)
Fournisseur Connectez-vous pour afficher

Détail du produit anti-PAK2 anticorps

Détail du antigène PAK2 Information d'application Stockage Images
Specificité This antibody detects PAK2 at C-term.
Réactivité croisée (Details) Species reactivity (tested):Human, mouse, rat
Purification Peptide affinity chromatography
Immunogène 14 amino acid peptide from near the carboxy terminus of human PAK2
Isotype IgG

Détail du antigène PAK2

Détail du produit anti-PAK2 anticorps Information d'application Stockage Images Haut de la page
Antigène
Autre désignation PAK2 (PAK2 Antibody Extrait)
Sujet The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6, and are not activated by Cdc42/Rac binding. Of the six PAK proteins, only PAK2 is ubiquitously expressed and cleaved by caspase-3. This cleavage removes the amino-terminal regulatory domain and generates a constitutively active kinase fragment. Recent experiments have shown that following cleavage, the active fragment is myristoylated and directed to the plasma membrane and membrane ruffles where it promotes cell death via increased signaling through the c-Jun N-terminal kinase pathway, but without compromising mitochondrial integrity.Synonyms: Gamma-PAK, PAK 2, PAK gamma, PAK-2, PAK65, Serine/threonine-protein kinase PAK 2, p21-activated kinase 2, p58
ID gène 5062
NCBI Accession NP_002568
UniProt Q13177
Domaine de recherche Apoptosis/Necrosis, Cancer, Kinases/Phosphatases, Tyrosine Kinases
Pathways Signalisation MAPK, Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha

Information d'application

Détail du produit anti-PAK2 anticorps Détail du antigène PAK2 Stockage Images Haut de la page
Indications d'application ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-PAK2 anticorps Détail du antigène PAK2 Information d'application Images Haut de la page
Concentration 1 mg/mL
Buffer PBS containing 0.02 % sodium azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store at 2 - 8 °C.