Aperçu des produits pour anti-RPS6KA3 (RPS6KA3) Anticorps

Full name:
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 Anticorps (RPS6KA3)
Chez www.anticorps-enligne.fr sont 153 Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) Anticorps de 19 de différents fournisseurs disponibles. De plus, nous expédions RPS6KA3 Protéines (13) et RPS6KA3 Kits (1) et beaucoup plus de produits pour cette protéine. Un total de 178 RPS6KA3 produits sont actuellement listés.
CLS, HU-3, ISPK-1, MAPKAPK1B, MPK-9, MRX19, p90-RSK2, pp90RSK2, RSK, RSK2, S6K-alpha3
afficher tous les anticorps Gène GeneID UniProt
RPS6KA3 110651 P18654
RPS6KA3 6197 P51812

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anti-Mouse (Murine) RPS6KA3 Anticorps:

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anti-RPS6KA3 Anticorps mieux référencés

  1. Human Polyclonal RPS6KA3 Primary Antibody pour EIA - ABIN358394 : Yang, Matsuda, Bialek, Jacquot, Masuoka, Schinke, Li, Brancorsini, Sassone-Corsi, Townes, Hanauer, Karsenty: ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. dans Cell 2004 (PubMed)
    Show all 5 references for 358394

  2. Human Monoclonal RPS6KA3 Primary Antibody pour ICC, FACS - ABIN969386 : Dehan, Bassermann, Guardavaccaro, Vasiliver-Shamis, Cohen, Lowes, Dustin, Huang, Taunton, Pagano: betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis. dans Molecular cell 2009 (PubMed)
    Show all 2 references for 969386

  3. Human Monoclonal RPS6KA3 Primary Antibody pour EIA, IF - ABIN1108903 : Koutsilieris, Mitsiades, Bogdanos, Dimopoulos, Karamanolakis, Milathianakis, Tsintavis: Combination of somatostatin analog, dexamethasone, and standard androgen ablation therapy in stage D3 prostate cancer patients with bone metastases. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2004 (PubMed)

Plus d’anticorps contre RPS6KA3 partenaires d’interaction

Mouse (Murine) Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) interaction partners

  1. The purified protein can be fully activated in vitro by phosphorylation with protein kinases ERK2 (Montrer MAPK1 Anticorps) and PDK1 (Montrer PDPK1 Anticorps).

  2. Downregulation of Rps6ka3 is a promising strategy for the treatment of multiple sclerosis.

  3. Data show that the phosphoinositide-dependent kinase 1 (PDK1 (Montrer PDPK1 Anticorps))-p90 (Montrer GPAM Anticorps) kDa ribosomal S6 kinases (Rsks) Rsk1 (Montrer RPS6KA1 Anticorps)/2 pathway is critical for establishment and maintenance of a normal Langerhans cells (LC) network.

  4. RSK2 regulates craniofacial development including tooth development and patterning via novel transcriptional targets

  5. The results of this study show that RSK2 loss-of-function is associated in the dentate gyrus with multi-level alterations that encompass modifications of glutamate (Montrer GRIN1 Anticorps) receptor channel properties, synaptic transmission.

  6. We propose that loss of function mutations in RSK2 that lead to Coffin-Lowry syndrome are related to defects in neuronal growth due to impaired RSK2-dependent PLD1 activity resulting in a reduced vesicle fusion rate and membrane supply.

  7. RSK2 interacted and phosphorylated GSK-3beta (Montrer GSK3b Anticorps) at Ser9. Notably, GSK-3beta (Montrer GSK3b Anticorps) phosphorylation at Ser9 was suppressed in RSK2(-/-) mouse embryonic fibroblasts.

  8. Pin1 (Montrer PIN1 Anticorps) plays a critical role in tumorigenesis plausibly via physical interaction with RSK2 and reciprocal phosphorylation

  9. This study showed that RSK2 signaling contributes to morphine analgesia in the tail withdrawal response.

  10. Results show increased protein levels of Rsk1 (Montrer RPS6KA1 Anticorps) and Rsk2 in the striatum of Huntington disease (Montrer HTT Anticorps) mice and and striatal cells transfected with full-length mutant Huntingtin (Montrer HTT Anticorps).

Human Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) interaction partners

  1. we discuss the function of the RSK2 signaling axis by interactions with binding partners in cancer development--{REVIEW}

  2. Results showed that RSK2 gene was overexpressed in osteosarcoma patients cells and its knockdown increased cell apoptosis, enhanced cell chemosensitivity, inhibits proliferation and migration, and weakened tumor formation.

  3. Upregulated expression of RSK2 is associated with breast cancer.

  4. Data show that the 90 kDa ribosomal protein S6 (Montrer RPS6 Anticorps) kinases RSK1 (Montrer RPS6KA1 Anticorps) and RSK2 play a key role in the homing of ovarian cancer cells in metastatic sites by regulating cell adhesion and invasion.

  5. RSK1 (Montrer RPS6KA1 Anticorps) and 3 but not RSK2 are down-regulated in breast tumour and are associated with disease progression. RSK (Montrer RPS6KA1 Anticorps) may be a key component in the progression and metastasis of breast cancer.

  6. This case is one of the few examples where RPS6KA3 mutations are associated with a non-specific X-linked mental retardation.

  7. Results indicate that the phosphorylation of EphA2 (Montrer EPHA2 Anticorps) at Ser (Montrer SIGLEC1 Anticorps)-897 is controlled by RSK (Montrer RPS6KA1 Anticorps) and the RSK (Montrer RPS6KA1 Anticorps)-EphA2 (Montrer EPHA2 Anticorps) axis might contribute to cell motility and promote tumour malignant progression.

  8. miR (Montrer MLXIP Anticorps)-191 represses proliferation in primary human fibroblasts via targeting multiple proto-oncogenes, including CDK9 (Montrer CDK9 Anticorps), NOTCH2 (Montrer NOTCH2 Anticorps), and RPS6KA3.

  9. This is the first report of exon skipping from an exonic mutation of RPS6KA3, demonstrating that a missense mutation and concomitant disruption of normal splicing contribute to the manifestation of CLS (Montrer CLS Anticorps)

  10. SL0101 and BI-D1870 induce distinct off-target effects in mTORC1-p70S6K (Montrer RPS6KB1 Anticorps) signaling, and thus, the functions previously ascribed to RSK1 (Montrer RPS6KA1 Anticorps)/2 based on these inhibitors should be reassessed.

RPS6KA3 profil antigène

Antigen Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

Alternative names and synonyms associated with RPS6KA3

  • ribosomal protein S6 kinase polypeptide 3 (Rps6ka3) anticorps
  • ribosomal protein S6 kinase, 90kDa, polypeptide 3 (RPS6KA3) anticorps
  • CLS anticorps
  • HU-3 anticorps
  • ISPK-1 anticorps
  • MAPKAPK1B anticorps
  • MPK-9 anticorps
  • MRX19 anticorps
  • p90-RSK2 anticorps
  • pp90RSK2 anticorps
  • RSK anticorps
  • RSK2 anticorps
  • S6K-alpha3 anticorps

Protein level used designations for RPS6KA3

90 kDa ribosomal protein S6 kinase 3 , MAP kinase-activated protein kinase 1b , MAPK-activated protein kinase 1b , MAPKAP kinase 1b , MAPKAPK-1b , RSK-2 , S6K-alpha-3 , p90-RSK 3 , p90RSK3 , ribosomal S6 kinase 2 , ribosomal protein S6 kinase 2 , ribosomal protein S6 kinase alpha-3 , insulin-stimulated protein kinase 1

110651 Mus musculus
6197 Homo sapiens
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