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Aperçu des produits pour anti-IKBKG (IKBKG) Anticorps

Full name:
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma Anticorps (IKBKG)
Chez www.anticorps-enligne.fr sont 318 Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) Anticorps de 30 de différents fournisseurs disponibles. De plus, nous expédions IKBKG Kits (13) et IKBKG Protéines (11) et beaucoup plus de produits pour cette protéine. Un total de 360 IKBKG produits sont actuellement listés.
Synonymes:
1110037D23Rik, AI848108, AI851264, AMCBX1, AW124339, CG16910, dIKK, dIKK-gamma, Dmel\\CG16910, DmIKK-gamma, dmIKKgamma, FIP-3, FIP3, Fip3p, fj33c07, IKBKG, IKBKG_1, IKBKG_2, IKK, IKK-gamma, IKKg, IKKgamma, IKK[g], IKK[[gamma]], IP, IP1, IP2, IPD2, Kenny, Key, MGC97885, Nemo, wu:fj33c07, ZC2HC9, zgc:113492

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anti-Human IKBKG Anticorps:

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anti-IKBKG Anticorps mieux référencés

  1. Human Monoclonal IKBKG Primary Antibody pour WB - ABIN387828 : Mooster, Cancrini, Simonetti, Rossi, Di Matteo, Romiti, Di Cesare, Notarangelo, Geha, McDonald: Immune deficiency caused by impaired expression of nuclear factor-kappaB essential modifier (NEMO) because of a mutation in the 5' untranslated region of the NEMO gene. dans The Journal of allergy and clinical immunology 2010 (PubMed)
    Show all 6 references for ABIN387828

  2. Human Monoclonal IKBKG Primary Antibody pour FACS, WB - ABIN252492 : Harhaj, Sun: IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein. dans The Journal of biological chemistry 1999 (PubMed)
    Show all 5 references for ABIN252492

  3. Human Monoclonal IKBKG Primary Antibody pour WB - ABIN567773 : Iha, Kibler, Yedavalli, Peloponese, Haller, Miyazato, Kasai, Jeang: Segregation of NF-kappaB activation through NEMO/IKKgamma by Tax and TNFalpha: implications for stimulus-specific interruption of oncogenic signaling. dans Oncogene 2003 (PubMed)
    Show all 2 references for ABIN567773

  4. Human Monoclonal IKBKG Primary Antibody pour IHC (p), IP - ABIN567775 : Chu, Shin, Yang, DiDonato, Ballard: IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1. dans The Journal of biological chemistry 1999 (PubMed)
    Show all 2 references for ABIN567775

  5. Human Polyclonal IKBKG Primary Antibody pour IF, ELISA - ABIN1532742 : Rothwarf, Zandi, Natoli, Karin: IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex. dans Nature 1998 (PubMed)

  6. Human Polyclonal IKBKG Primary Antibody pour ELISA, WB - ABIN1534228 : Xiao, Sun: Activation of IKKalpha and IKKbeta through their fusion with HTLV-I tax protein. dans Oncogene 2000 (PubMed)

  7. Cow (Bovine) Polyclonal IKBKG Primary Antibody pour WB - ABIN2779233 : Salminen, Suuronen, Huuskonen, Kaarniranta: NEMO shuttle: a link between DNA damage and NF-kappaB activation in progeroid syndromes? dans Biochemical and biophysical research communications 2008 (PubMed)

  8. Cow (Bovine) Polyclonal IKBKG Primary Antibody pour WB - ABIN2779232 : Hai, Yeung, Wood, Wei, Yamaoka, Gatalica, Jeang, Brasier: An alternative splice product of IkappaB kinase (IKKgamma), IKKgamma-delta, differentially mediates cytokine and human T-cell leukemia virus type 1 tax-induced NF-kappaB activation. dans Journal of virology 2006 (PubMed)

Plus d’anticorps contre IKBKG partenaires d’interaction

Human Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) interaction partners

  1. Consistent with experimental evidence, the zinc ion is essential for mechanical stabilization of the functional, folded conformation of NEMO.

  2. Autoubiquitination of TRIM26 (Montrer TRIM26 Anticorps) links TBK1 (Montrer TBK1 Anticorps) to NEMO in RLR (Montrer DHX58 Anticorps)-mediated innate antiviral immune response

  3. Herein, our simulations of the zinc finger NEMO (2JVX) using multiple simulations of length 15, 30, 1000, and 3000 ns are analyzed to provide clarity on this point.

  4. Deletion of exons 4 to 10 (NEMODelta4-10) accounts for about 80% of cases (familial and sporadic) of Incontinentia pigmenti.

  5. results further reveal that cFLIPLrequires the linear ubiquitin chain assembly complex and the kinase TAK1 (Montrer MAP3K7 Anticorps) for activation of the IKK (Montrer CHUK Anticorps) kinase

  6. USP18 (Montrer USP18 Anticorps) negatively regulates NF-kappaB (Montrer NFKB1 Anticorps) signaling by targeting TAK1 (Montrer MAP3K7 Anticorps) and NEMO for deubiquitination through distinct mechanisms.

  7. A missense mutation in IKBKG causes a Nager syndrome or an atypical incontinentia pigmenti phenotype. IKBKG mutations are typically associated with preterm male death, but this variant is associated with survival for 8-15 days.

  8. Recruitment of A20 (Montrer TNFAIP3 Anticorps) to the C-terminal domain of NEMO represents a novel mechanism limiting NF-kappaB (Montrer NFKB1 Anticorps) activation by NEMO, and its absence results in autoinflammatory disease.

  9. Authors show that Rab11 (Montrer RAB11A Anticorps)-GMPPNP-FIP3-Rabin8 (Montrer RAB3IP Anticorps) is more stable than Rab11 (Montrer RAB11A Anticorps)-GMPPNP-Rabin8 (Montrer RAB3IP Anticorps), owing to direct interaction between Rabin8 (Montrer RAB3IP Anticorps) and FIP3 within the dual effector-bound complex.

  10. Somatic mosaicism of a novel IKBKG nonsense mutation in a male patient with incontinentia pigmenti.

Pig (Porcine) Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) interaction partners

  1. Nsp4 interfered with the NF-kappaB (Montrer NFKB1 Anticorps) signaling pathway through the cleavage of IKBKG at the E349-S350 site, leading to the downregulation of IFN-beta (Montrer IFNB1 Anticorps) production.

  2. Foot-and-mouth disease virus 3C protease cleaves NEMO to impair innate immune signaling.

Mouse (Murine) Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) interaction partners

  1. Whereas Parkin (Montrer PARK2 Anticorps) has been reported to positively regulate the expression of OPA1 (Montrer MED12 Anticorps) through NEMO, herein we found that PARK2 (Montrer PARK2 Anticorps) overexpression did not modify the expression of OPA1 (Montrer MED12 Anticorps).

  2. prevents colon inflammation by NF-kappaB (Montrer NFKB1 Anticorps)-independent functions

  3. Thyrocyte-specific NEMO knock-out mice gradually develop hypothyroidism after birth, which leads to reduced body weight and shortened life span.

  4. SENP1 (Montrer SENP1 Anticorps) deletion in adipocytes causes Type 1 diabetes mellitus via enhanced SUMOylation of NEMO, leading to increased NF-kappaB (Montrer NFKB1 Anticorps) activity, cytokine production and pancreatic inflammation.

  5. Crucial functions of inflammatory TAK1 (Montrer NR2C2 Anticorps)-NEMO signaling in protecting the brain endothelium and maintaining normal brain function.

  6. Data show that NEMO protein prevents hepatocarcinogenesis by inhibiting receptor (TNFRSF)-interacting serine-threonine kinase 1 (RIPK1 (Montrer RIPK1 Anticorps)) kinase activity-driven hepatocyte apoptosis.

  7. Data show that the in utero death of NF-NF (Montrer NFASC Anticorps)-kappaB (Montrer NFKB1 Anticorps) essential modulator (NEMO) and cylindromatosis protein double mutant mice is mediated by TNF (Montrer TNF Anticorps) receptor 1 (TNFR1 (Montrer TNFRSF1A Anticorps)) signaling and can be rescued by TNFR1 (Montrer TNFRSF1A Anticorps) deficiency.

  8. signaling through NEMO might not only be involved in the production of NF-kappaB (Montrer NFKB1 Anticorps) proinflammatory chemokines but also regulates podocyte dynamics independently of NF-kappaB (Montrer NFKB1 Anticorps)

  9. The stability of the NEMO coiled coil is maintained by strong interhelix interactions in the region centered on residue 54.

  10. NEMO deficiency results in apoptosis, the development of liver fibrosis and hepatocellular carcinoma, all of which are substantially alleviated by allogeneic hepatocyte transplantation.

IKBKG profil antigène

Antigen Summary

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

Alternative names and synonyms associated with IKBKG

  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (ikbkg) anticorps
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG) anticorps
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (LOC782205) anticorps
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG_1) anticorps
  • kenny (key) anticorps
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (Ikbkg) anticorps
  • inhibitor of kappaB kinase gamma (Ikbkg) anticorps
  • 1110037D23Rik anticorps
  • AI848108 anticorps
  • AI851264 anticorps
  • AMCBX1 anticorps
  • AW124339 anticorps
  • CG16910 anticorps
  • dIKK anticorps
  • dIKK-gamma anticorps
  • Dmel\\CG16910 anticorps
  • DmIKK-gamma anticorps
  • dmIKKgamma anticorps
  • FIP-3 anticorps
  • FIP3 anticorps
  • Fip3p anticorps
  • fj33c07 anticorps
  • IKBKG anticorps
  • IKBKG_1 anticorps
  • IKBKG_2 anticorps
  • IKK anticorps
  • IKK-gamma anticorps
  • IKKg anticorps
  • IKKgamma anticorps
  • IKK[g] anticorps
  • IKK[[gamma]] anticorps
  • IP anticorps
  • IP1 anticorps
  • IP2 anticorps
  • IPD2 anticorps
  • Kenny anticorps
  • Key anticorps
  • MGC97885 anticorps
  • Nemo anticorps
  • wu:fj33c07 anticorps
  • ZC2HC9 anticorps
  • zgc:113492 anticorps

Protein level used designations for IKBKG

NF-kappa-B essential modulator , ikky , inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma , inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform 1 , inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform 2 , NF-kappa-B essential modulator-like , CG16910-PA , CG16910-PB , key-PA , key-PB , I-kappa-B kinase subunit gamma , IKKAP1 , IKKG , IkB kinase gamma subunit , NF-kappa-B essential modifier , NFkappaB essential modulator , ikB kinase subunit gamma , ikB kinase-associated protein 1 , incontinentia pigmenti , inhibitor of nuclear factor kappa-B kinase subunit gamma , I-kappa-B kinase gamma , IKK-gamma , NEMO , NF-kappa B essential modulator , inhibitor of kappaB kinase gamma , mFIP-3

GENE ID SPECIES
541530 Danio rerio
701237 Macaca mulatta
735069 Xenopus laevis
743415 Pan troglodytes
782205 Bos taurus
100137553 Papio anubis
100145270 Xenopus (Silurana) tropicalis
100470223 Ailuropoda melanoleuca
37967 Drosophila melanogaster
8517 Homo sapiens
612576 Canis lupus familiaris
100127355 Sus scrofa
281855 Bos taurus
100328905 Oryctolagus cuniculus
309295 Rattus norvegicus
16151 Mus musculus
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