Aperçu des produits pour anti-IKBKG (IKBKG) Anticorps

Full name:
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma Anticorps (IKBKG)
Chez www.anticorps-enligne.fr sont 340 Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) Anticorps de 31 de différents fournisseurs disponibles. De plus, nous expédions IKBKG Kits (16) et IKBKG Protéines (11) et beaucoup plus de produits pour cette protéine. Un total de 385 IKBKG produits sont actuellement listés.
Synonymes:
1110037D23Rik, AI848108, AI851264, AMCBX1, AW124339, CG16910, dIKK, dIKK-gamma, Dmel\\CG16910, DmIKK-gamma, dmIKKgamma, FIP-3, FIP3, Fip3p, fj33c07, IKBKG, IKBKG_1, IKBKG_2, IKK, IKK-gamma, IKKg, IKKgamma, IKK[g], IKK[[gamma]], IP, IP1, IP2, IPD2, Kenny, Key, MGC97885, Nemo, wu:fj33c07, ZC2HC9, zgc:113492

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anti-IKBKG Anticorps mieux référencés

  1. Human Monoclonal IKBKG Primary Antibody pour WB - ABIN387828 : Mooster, Cancrini, Simonetti, Rossi, Di Matteo, Romiti, Di Cesare, Notarangelo, Geha, McDonald: Immune deficiency caused by impaired expression of nuclear factor-kappaB essential modifier (NEMO) because of a mutation in the 5' untranslated region of the NEMO gene. dans The Journal of allergy and clinical immunology 2010 (PubMed)
    Show all 6 references for 387828

  2. Human Monoclonal IKBKG Primary Antibody pour FACS, WB - ABIN252492 : Harhaj, Sun: IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein. dans The Journal of biological chemistry 1999 (PubMed)
    Show all 5 references for 252492

  3. Human Monoclonal IKBKG Primary Antibody pour WB - ABIN567773 : Iha, Kibler, Yedavalli, Peloponese, Haller, Miyazato, Kasai, Jeang: Segregation of NF-kappaB activation through NEMO/IKKgamma by Tax and TNFalpha: implications for stimulus-specific interruption of oncogenic signaling. dans Oncogene 2003 (PubMed)
    Show all 2 references for 567773

  4. Human Monoclonal IKBKG Primary Antibody pour IHC (p), IP - ABIN567775 : Chu, Shin, Yang, DiDonato, Ballard: IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1. dans The Journal of biological chemistry 1999 (PubMed)
    Show all 2 references for 567775

  5. Human Polyclonal IKBKG Primary Antibody pour ELISA, WB - ABIN1534228 : Xiao, Sun: Activation of IKKalpha and IKKbeta through their fusion with HTLV-I tax protein. dans Oncogene 2000 (PubMed)

  6. Human Polyclonal IKBKG Primary Antibody pour IF, ELISA - ABIN1532742 : Rothwarf, Zandi, Natoli, Karin: IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex. dans Nature 1998 (PubMed)

  7. Cow (Bovine) Polyclonal IKBKG Primary Antibody pour WB - ABIN2779232 : Hai, Yeung, Wood, Wei, Yamaoka, Gatalica, Jeang, Brasier: An alternative splice product of IkappaB kinase (IKKgamma), IKKgamma-delta, differentially mediates cytokine and human T-cell leukemia virus type 1 tax-induced NF-kappaB activation. dans Journal of virology 2006 (PubMed)

  8. Cow (Bovine) Polyclonal IKBKG Primary Antibody pour WB - ABIN2779233 : Salminen, Suuronen, Huuskonen, Kaarniranta: NEMO shuttle: a link between DNA damage and NF-kappaB activation in progeroid syndromes? dans Biochemical and biophysical research communications 2008 (PubMed)

Plus d’anticorps contre IKBKG partenaires d’interaction

Human Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) interaction partners

  1. Authors show that NEMO stabilizes HIFalpha via direct interaction and independently of NF-kappaB (Montrer NFKB1 Anticorps) signaling in vitro. NEMO prolongs tumor cell survival via regulation of apoptosis and activation of epithelial-to-mesenchymal transition, facilitating tumor metastasis.

  2. The results demonstrate the the first example of father-to-daughter transmission of IP in which a pathogenic mutation in IKBKG has been demonstrated

  3. Molluscum contagiosum virus MC005 inhibited NF-kappaB (Montrer NFKB1 Anticorps) proximal to the IkappaB kinase (Montrer CHUK Anticorps) (IKK (Montrer CHUK Anticorps)) complex, and unbiased affinity purification revealed that MC005 interacts with the IKK (Montrer CHUK Anticorps) subunit NEMO (NF-kappaB (Montrer NFKB1 Anticorps) essential modulator).

  4. These data suggest that molluscum contagiosum virus MC159 competitively binds to NEMO to prevent cIAP1 (Montrer BIRC2 Anticorps)-induced NEMO polyubiquitination.

  5. High IKBKG expression is associated with multiple myeloma.

  6. Our findings shed light on the nature of the interaction between NEMO and poly-ubiquitin, suggesting that NEMO is differentially regulated by poly-ubiquitin chain length and that this regulation occurs via a modulation of the available equilibrium of conformational states, rather than gross structural change

  7. FADD (Montrer FADD Anticorps), as well as NEMO, is a substrate for LUBAC ubiquitin ligase (E3) complex, composed of the HOIP (Montrer RNF31 Anticorps), HOIL-1L (Montrer RBCK1 Anticorps), and SHARPIN (Montrer SHARPIN Anticorps) subunits.

  8. Consistent with experimental evidence, the zinc ion is essential for mechanical stabilization of the functional, folded conformation of NEMO.

  9. Autoubiquitination of TRIM26 (Montrer TRIM26 Anticorps) links TBK1 (Montrer TBK1 Anticorps) to NEMO in RLR (Montrer DHX58 Anticorps)-mediated innate antiviral immune response

  10. Herein, our simulations of the zinc finger NEMO (2JVX) using multiple simulations of length 15, 30, 1000, and 3000 ns are analyzed to provide clarity on this point.

Pig (Porcine) Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) interaction partners

  1. Porcine deltacoronavirus nsp5 (Montrer SPECC1 Anticorps), the 3C-like protease, inhibits interferon-beta (Montrer IFNB1 Anticorps) production through the cleavage of NEMO.

  2. Nsp4 interfered with the NF-kappaB (Montrer NFKB1 Anticorps) signaling pathway through the cleavage of IKBKG at the E349-S350 site, leading to the downregulation of IFN-beta (Montrer IFNB1 Anticorps) production.

  3. Foot-and-mouth disease virus 3C protease cleaves NEMO to impair innate immune signaling.

Mouse (Murine) Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) interaction partners

  1. lymphocyte-specific deletion of IKK2 (Montrer IKBKB Anticorps) or NEMO aggravated kidney injury after ischemia-reperfusion injury, and, in both conditions, the percentage of Th17 cells was increased.

  2. Whereas Parkin (Montrer PARK2 Anticorps) has been reported to positively regulate the expression of OPA1 (Montrer MED12 Anticorps) through NEMO, herein we found that PARK2 (Montrer PARK2 Anticorps) overexpression did not modify the expression of OPA1 (Montrer MED12 Anticorps).

  3. prevents colon inflammation by NF-kappaB (Montrer NFKB1 Anticorps)-independent functions

  4. Thyrocyte-specific NEMO knock-out mice gradually develop hypothyroidism after birth, which leads to reduced body weight and shortened life span.

  5. SENP1 (Montrer SENP1 Anticorps) deletion in adipocytes causes Type 1 diabetes mellitus via enhanced SUMOylation of NEMO, leading to increased NF-kappaB (Montrer NFKB1 Anticorps) activity, cytokine production and pancreatic inflammation.

  6. Crucial functions of inflammatory TAK1 (Montrer NR2C2 Anticorps)-NEMO signaling in protecting the brain endothelium and maintaining normal brain function.

  7. Data show that NEMO protein prevents hepatocarcinogenesis by inhibiting receptor (TNFRSF)-interacting serine-threonine kinase 1 (RIPK1 (Montrer RIPK1 Anticorps)) kinase activity-driven hepatocyte apoptosis.

  8. Data show that the in utero death of NF-NF (Montrer NFASC Anticorps)-kappaB (Montrer NFKB1 Anticorps) essential modulator (NEMO) and cylindromatosis protein double mutant mice is mediated by TNF (Montrer TNF Anticorps) receptor 1 (TNFR1 (Montrer TNFRSF1A Anticorps)) signaling and can be rescued by TNFR1 (Montrer TNFRSF1A Anticorps) deficiency.

  9. signaling through NEMO might not only be involved in the production of NF-kappaB (Montrer NFKB1 Anticorps) proinflammatory chemokines but also regulates podocyte dynamics independently of NF-kappaB (Montrer NFKB1 Anticorps)

  10. The stability of the NEMO coiled coil is maintained by strong interhelix interactions in the region centered on residue 54.

IKBKG profil antigène

Antigen Summary

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

Alternative names and synonyms associated with IKBKG

  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (ikbkg) anticorps
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG) anticorps
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (LOC782205) anticorps
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG_1) anticorps
  • kenny (key) anticorps
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (Ikbkg) anticorps
  • inhibitor of kappaB kinase gamma (Ikbkg) anticorps
  • 1110037D23Rik anticorps
  • AI848108 anticorps
  • AI851264 anticorps
  • AMCBX1 anticorps
  • AW124339 anticorps
  • CG16910 anticorps
  • dIKK anticorps
  • dIKK-gamma anticorps
  • Dmel\\CG16910 anticorps
  • DmIKK-gamma anticorps
  • dmIKKgamma anticorps
  • FIP-3 anticorps
  • FIP3 anticorps
  • Fip3p anticorps
  • fj33c07 anticorps
  • IKBKG anticorps
  • IKBKG_1 anticorps
  • IKBKG_2 anticorps
  • IKK anticorps
  • IKK-gamma anticorps
  • IKKg anticorps
  • IKKgamma anticorps
  • IKK[g] anticorps
  • IKK[[gamma]] anticorps
  • IP anticorps
  • IP1 anticorps
  • IP2 anticorps
  • IPD2 anticorps
  • Kenny anticorps
  • Key anticorps
  • MGC97885 anticorps
  • Nemo anticorps
  • wu:fj33c07 anticorps
  • ZC2HC9 anticorps
  • zgc:113492 anticorps

Protein level used designations for IKBKG

NF-kappa-B essential modulator , ikky , inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma , inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform 1 , inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform 2 , NF-kappa-B essential modulator-like , CG16910-PA , CG16910-PB , key-PA , key-PB , I-kappa-B kinase subunit gamma , IKKAP1 , IKKG , IkB kinase gamma subunit , NF-kappa-B essential modifier , NFkappaB essential modulator , ikB kinase subunit gamma , ikB kinase-associated protein 1 , incontinentia pigmenti , inhibitor of nuclear factor kappa-B kinase subunit gamma , I-kappa-B kinase gamma , IKK-gamma , NEMO , NF-kappa B essential modulator , inhibitor of kappaB kinase gamma , mFIP-3

GENE ID SPECIES
541530 Danio rerio
701237 Macaca mulatta
735069 Xenopus laevis
743415 Pan troglodytes
782205 Bos taurus
100137553 Papio anubis
100145270 Xenopus (Silurana) tropicalis
100470223 Ailuropoda melanoleuca
37967 Drosophila melanogaster
8517 Homo sapiens
612576 Canis lupus familiaris
100127355 Sus scrofa
281855 Bos taurus
100328905 Oryctolagus cuniculus
309295 Rattus norvegicus
16151 Mus musculus
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