Aperçu des produits pour anti-KHDRBS1 (KHDRBS1) Anticorps

Full name:
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 Anticorps (KHDRBS1)
Chez www.anticorps-enligne.fr sont 128 KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) Anticorps de 19 de différents fournisseurs disponibles. De plus, nous expédions KHDRBS1 Protéines (11) et KHDRBS1 Kits (9) et beaucoup plus de produits pour cette protéine. Un total de 154 KHDRBS1 produits sont actuellement listés.
Synonymes:
A170, fj90g10, KHDRBS1, OSIL, p60, P62, p62B, p68, PDB3, Sam68, wu:fa18g12, wu:fa56c01, wu:fc91b01, wu:fj90g10, zgc:113899, ZIP3

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anti-Human KHDRBS1 Anticorps:

anti-Mouse (Murine) KHDRBS1 Anticorps:

anti-Rat (Rattus) KHDRBS1 Anticorps:

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anti-KHDRBS1 Anticorps mieux référencés

  1. Human Polyclonal KHDRBS1 Primary Antibody pour ICC, IF - ABIN4351941 : Lawrence, Schafer, Rieder: The nuclear protein Sam68 is cleaved by the FMDV 3C protease redistributing Sam68 to the cytoplasm during FMDV infection of host cells. dans Virology 2012 (PubMed)
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  2. Cow (Bovine) Polyclonal KHDRBS1 Primary Antibody pour IHC, WB - ABIN2778999 : Duran, Linares, Galvez, Wikenheiser, Flores, Diaz-Meco, Moscat: The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis. dans Cancer cell 2008 (PubMed)

  3. Human Polyclonal KHDRBS1 Primary Antibody pour EIA, IHC (fro) - ABIN1108931 : Grange, Belly, Dupas, Trembleau, Sadoul, Goldberg: Specific interaction between Sam68 and neuronal mRNAs: implication for the activity-dependent biosynthesis of elongation factor eEF1A. dans Journal of neuroscience research 2008 (PubMed)

  4. Cow (Bovine) Polyclonal KHDRBS1 Primary Antibody pour WB - ABIN2779966 : Paronetto, Zalfa, Botti, Geremia, Bagni, Sette: The nuclear RNA-binding protein Sam68 translocates to the cytoplasm and associates with the polysomes in mouse spermatocytes. dans Molecular biology of the cell 2005 (PubMed)

Plus d’anticorps contre KHDRBS1 partenaires d’interaction

Human KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) interaction partners

  1. SQSTM1-Nup214, although mostly cytoplasmic, also forms nuclear bodies and inhibits nuclear protein but not poly(A)(+) RNA export.

  2. autophagy upregulation by Sequestosome 1 (p62 (Montrer SQSTM1 Anticorps)/SQSM1) knockdown ameliorated this cell injury and relieved insulin (Montrer INS Anticorps) resistance

  3. This work suggests that UVA-induced p62 (Montrer GTF2H1 Anticorps) acts through COX-2 (Montrer COX2 Anticorps) to promote skin tumor growth and progression.

  4. we provide evidence that p62 (Montrer GTF2H1 Anticorps) is implicated in the activation of NF-kappaB (Montrer NFKB1 Anticorps) signaling that is partly dependent on RIP1 (Montrer UQCRFS1 Anticorps)

  5. In this study, we first observed that p62-positive intranuclear aggregates also appeared in controls and were not specific for the Neuronal Intranuclear Hyaline Inclusion Disease cases.

  6. Data suggest that phosphorylation of SQSTM1 (Montrer SQSTM1 Anticorps) by AMP-activated protein kinase (AMPK (Montrer PRKAA2 Anticorps)) and translocation of SQSTM1 (Montrer SQSTM1 Anticorps) to mitochondria drives autophagic cell death in adult hippocampal neural stem cells; activation of AMPK (Montrer PRKAA1 Anticorps) promotes autophagic cell death; inhibition of AMPK (Montrer PRKAA1 Anticorps) (by enzyme inhibitor or RNA interference) suppresses autophagic cell death. (SQSTM1 (Montrer SQSTM1 Anticorps) = sequestosome 1 (Montrer SQSTM1 Anticorps))

  7. Data suggest that the first 22 bp of exon 3 in BIRC5 (Montrer BIRC5 Anticorps) contain cis (Montrer CISH Anticorps)-acting elements that enhance the exclusion of exon 3 to generate the survivin (Montrer BIRC5 Anticorps) DEx3 mRNA isoform via exclusion/deletion of exon 3; Sam68 is a possible trans-acting factor that binds to this cis (Montrer CISH Anticorps)-acting element and regulates exon 3 splicing. (BIRC5/survivin (Montrer BIRC5 Anticorps) = baculoviral IAP repeat containing 5 (Montrer BIRC5 Anticorps); Sam68 = GAP-associated tyrosine phosphoprotein p62)

  8. our results indicated that Sam68 modulates apoptosis of intestinal epithelial cells via mediating NF-kappaB (Montrer NFKB1 Anticorps) activation in ulcerative colitis

  9. Authors found that p62/SQSTM1 (Montrer SQSTM1 Anticorps), a protein upregulated in liver parenchymal cells but downregulated in HCC (Montrer FAM126A Anticorps)-associated HSCs, negatively controls hepatic stellate cells activation.

  10. necessary for retinal pigmented epithelial cytoprotection under oxidative stress; NFkappaB p65 activity may be critical upstream initiator of p62 expression in retinal pigmented epithelial cells under oxidative stress

Mouse (Murine) KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) interaction partners

  1. our results indicated that Sam68 modulates apoptosis of intestinal epithelial cells via mediating NF-kappaB (Montrer NFKB1 Anticorps) activation in ulcerative colitis

  2. Sam68 may function as an immune rheostat that balances the activation of NF-kappaB (Montrer NFKB1 Anticorps) p65 (Montrer NFkBP65 Anticorps) and c-Rel (Montrer NFkBP65 Anticorps), as well as MAPK (Montrer MAPK1 Anticorps), revealing a potential novel target to manipulate TLR signaling.

  3. Sam68 plays a crucial role in DNA damage response via regulating DNA damage-initiated PAR (Montrer AFG3L2 Anticorps) production.

  4. Sam68 is essential for DNA damage-induced NF-kappaB (Montrer NFKB1 Anticorps) activation and colon tumorigenesis.

  5. Sam68 and T-STAR (Montrer KHDRBS3 Anticorps) could regulate alternative splicing of some pre-mRNAs by bringing two distant UAA motifs into proximity and looping out regions of the pre-mRNA.

  6. SAM68 is a physiological regulator of SMN2 (Montrer SMN1 Anticorps) splicing in a spinal muscular atrophy mouse model.

  7. Data (including data from knockout mice) suggest expression of Sam68 plays role in adipogenesis of white adipose tissue versus brown adipose tissue; Sam68 appears to regulate adiposity and energy homeostasis (balance of energy intake/expenditure).

  8. Depletion of p31S6K1 with small interfering RNAs (siRNAs) partially restored adipogenesis of Sam68-deficient preadipocytes.

  9. Emerging roles for Sam68 in adipogenesis and neuronal development.

  10. Our research identifies a role for Sam68 in synaptodendritic posttranscriptional regulation of actb (Montrer ACTB PLURAL_@14456@) and may provide insight into the pathophysiology of fragile X (Montrer FMR1 PLURAL_@14456@) tremor/ataxia (Montrer USP14 PLURAL_@14456@) syndrome

KHDRBS1 profil antigène

Antigen Summary

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Alternative names and synonyms associated with KHDRBS1

  • KH domain containing, RNA binding, signal transduction associated 1a (khdrbs1a) anticorps
  • KH domain containing, RNA binding, signal transduction associated 1 (KHDRBS1) anticorps
  • KH domain containing, RNA binding, signal transduction associated 1 (khdrbs1) anticorps
  • KH domain containing, RNA binding, signal transduction associated 1 (Khdrbs1) anticorps
  • sequestosome 1 (SQSTM1) anticorps
  • A170 anticorps
  • fj90g10 anticorps
  • KHDRBS1 anticorps
  • OSIL anticorps
  • p60 anticorps
  • P62 anticorps
  • p62B anticorps
  • p68 anticorps
  • PDB3 anticorps
  • Sam68 anticorps
  • wu:fa18g12 anticorps
  • wu:fa56c01 anticorps
  • wu:fc91b01 anticorps
  • wu:fj90g10 anticorps
  • zgc:113899 anticorps
  • ZIP3 anticorps

Protein level used designations for KHDRBS1

GAP-associated phosphoprotein p62 , KH domain containing, RNA binding, signal transduction associated 1 , fa18g12 , fa56c01 , fc91b01 , GAP-associated tyrosine phosphoprotein p62 (Sam68) , KH domain-containing, RNA-binding, signal transduction-associated protein 1 , p21 Ras GTPase-activating protein-associated p62 , src-associated in mitosis 68 kDa protein , GAP-associated tyrosine phosphoprotein p62 , src associated in mitosis, 68 kDa , p68 , KH domain RNA-binding protein Sam68 , sam68 , EBI3-associated protein of 60 kDa , EBI3-associated protein p60 , EBIAP , oxidative stress induced like , phosphotyrosine independent ligand for the Lck SH2 domain p62 , phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa , sequestosome-1 , ubiquitin-binding protein p62

GENE ID SPECIES
30082 Danio rerio
456705 Pan troglodytes
487316 Canis lupus familiaris
549799 Xenopus (Silurana) tropicalis
100025483 Monodelphis domestica
10657 Homo sapiens
538775 Bos taurus
20218 Mus musculus
117268 Rattus norvegicus
398660 Xenopus laevis
374071 Gallus gallus
8878 Homo sapiens
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