Aperçu des produits pour anti-MAP3K7 (MAP3K7) Anticorps

Full name:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 Anticorps (MAP3K7)
Chez www.anticorps-enligne.fr sont 177 Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Anticorps de 16 de différents fournisseurs disponibles. De plus, nous expédions MAP3K7 Kits (10) et MAP3K7 Protéines (7) et beaucoup plus de produits pour cette protéine. Un total de 214 MAP3K7 produits sont actuellement listés.
Synonymes:
B430101B05, C87327, MEKK7, si:ch211-225h9.1, TAK1, TGF1a, zgc:110612

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anti-MAP3K7 Anticorps mieux référencés

  1. Human Polyclonal MAP3K7 Primary Antibody pour EIA - ABIN358291 : Ono, Ohtomo, Ninomiya-Tsuji, Tsuchiya: A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta. dans Biochemical and biophysical research communications 2003 (PubMed)
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  2. Human Polyclonal MAP3K7 Primary Antibody pour DB, EIA - ABIN358312 : Smit, Baas, Kuipers, Korswagen, van de Wetering, Clevers: Wnt activates the Tak1/Nemo-like kinase pathway. dans The Journal of biological chemistry 2004 (PubMed)
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  3. Human Polyclonal MAP3K7 Primary Antibody pour EIA, IHC (p) - ABIN360354 : Takaesu, Surabhi, Park, Ninomiya-Tsuji, Matsumoto, Gaynor: TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway. dans Journal of molecular biology 2003 (PubMed)
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  4. Human Polyclonal MAP3K7 Primary Antibody pour ELISA, WB - ABIN185640 : Omori, Matsumoto, Sanjo, Sato, Akira, Smart, Ninomiya-Tsuji: TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis. dans The Journal of biological chemistry 2006 (PubMed)
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  5. Human Polyclonal MAP3K7 Primary Antibody pour IHC, ELISA - ABIN1532056 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... dans Nature 2003 (PubMed)
    Show all 2 references for 1532056

  6. Human Polyclonal MAP3K7 Primary Antibody pour ELISA, WB - ABIN1532055 : Shibuya, Yamaguchi, Shirakabe, Tonegawa, Gotoh, Ueno, Irie, Nishida, Matsumoto: TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. dans Science (New York, N.Y.) 1996 (PubMed)
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Plus d’anticorps contre MAP3K7 partenaires d’interaction

Human Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) interaction partners

  1. TAK1 regulates Nrf2 (Montrer GABPA Anticorps) through modulation of Keap-p62/SQSTM1 (Montrer SQSTM1 Anticorps) interaction. This regulation is important for homeostatic antioxidant protection in the intestinal epithelium.

  2. Overexpression of TAK1 was strongly associated with positive lymph node metastasis in pancreatic ductal adenocarcinoma.

  3. dysregulation of the TAK1 complex produces a close phenocopy of Frontometaphyseal Dysplasia caused by FLNA (Montrer FLNA Anticorps) mutations; furthermore, the pathogenesis of some of the filaminopathies caused by FLNA (Montrer FLNA Anticorps) mutations might be mediated by misregulation of signaling coordinated through the TAK1 signaling complex

  4. although TAK1 is located at the crossroad of inflammation, immunity, and cancer, this study reports MAP3K7 mutations in a developmental disorder affecting mainly cartilage, bone, and heart

  5. This study suggests that aberrant activity of TAK1 impairs autophagy and subsequently leads to alterations in the vitality of retinal pigment epithelial cells.

  6. TAK1 may be an important factor involved in the pathogenesis of thyroid cancer, and targeted down-regulation of TAK1 may improve the prognosis of patients with thyroid cancer.

  7. Loss of MAP3K7 are associated with esophageal squamous cell carcinoma.

  8. This paper highlights that targeting the BMP and TGFbeta (Montrer TGFB1 Anticorps) type I and type II receptors causes a downregulation of XIAP (Montrer XIAP Anticorps), TAK1, and Id1 (Montrer ID1 Anticorps) leading to cell death of lung cancer cells.

  9. Polyubiquitination of Transforming Growth Factor beta-activated Kinase 1 (TAK1) at Lysine 562 Residue Regulates TLR4 (Montrer TLR4 Anticorps)-mediated JNK (Montrer MAPK8 Anticorps) and p38 MAPK (Montrer MAPK14 Anticorps) Activation

  10. The data emphasize the central role of TAK1 in controlling signaling cascades and functional responses in primary neutrophils, making it a promising target for therapeutic intervention in view of the role of neutrophils in chronic inflammatory conditions.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) interaction partners

  1. Transforming growth factor-beta activated kinase 1 (TAK1) regulation of sterol-regulatory element-binding proteins (SREBPs) critically contributes to the maintenance of liver homeostasis to prevent steatosis, which is a potentially important mechanism to prevent hepatocellular carcinoma (HCC (Montrer FAM126A Anticorps)) development.

  2. TAK1 (Montrer NR2C2 Anticorps) regulates Nrf2 (Montrer NFE2L2 Anticorps) through modulation of Keap-p62/SQSTM1 (Montrer SQSTM1 Anticorps) interaction. This regulation is important for homeostatic antioxidant protection in the intestinal epithelium.

  3. Mekk1 (Montrer MAP2K1 Anticorps) (encoded by Map3k1 (Montrer MAP3K1 Anticorps)) signaling activates Mapks to regulate Cdkn1b (Montrer CDKN1B Anticorps) (encoding p27(Kip1 (Montrer CDKN1B Anticorps))) expression and p27(Kip1 (Montrer CDKN1B Anticorps))-dependent proliferative expansion in response to antigen.

  4. TRADD (Montrer TRADD Anticorps) knockout blunts pressure overload-induced cardiac hypertrophy through mediating TAK1 (Montrer NR2C2 Anticorps)/p38 MAPK (Montrer MAPK14 Anticorps) but not AKT (Montrer AKT1 Anticorps) phosphorylation

  5. this study demonstrates a pivotal role of TAK1 (Montrer NR2C2 Anticorps) in dendritic cells in controlling trichloroethylene-induced contact hypersensitivity response and suggests that targeting TAK1 (Montrer NR2C2 Anticorps) function in DCs may be a viable approach to preventing and treating TCE-related occupational health hazards

  6. The E3 ligase TRIM8 (Montrer TRIM8 Anticorps) is a potent regulator that exacerbates steatohepatitis and metabolic disorders dependent on its binding and ubiquitinating capacity on transforming growth factor-beta-activated kinase 1.

  7. Angiotensin-II up-regulates the Ampkalpha1 (Montrer PRKAA1 Anticorps) isoform in renal tissue. Ampkalpha1 (Montrer PRKAA1 Anticorps) participates in renal Tak1 (Montrer NR2C2 Anticorps) activation and Tak1 (Montrer NR2C2 Anticorps)-dependent signaling induced by angiotensin-II.

  8. TRIM8 (Montrer TRIM8 Anticorps) could promote K63-linked polyubiquitination of transforming growth factor beta-activated kinase 1 (TAK1), leading to the activation of TAK1 (Montrer NR2C2 Anticorps) and enhanced inflammatory responses.

  9. TAK1 (Montrer NR2C2 Anticorps) signaling preserved the viability of lambda-chain-positive B cells by maintaining Bcl-2 (Montrer BCL2 Anticorps) expression through IKK (Montrer CHUK Anticorps)-NF-kappaB (Montrer NFKB1 Anticorps) signaling

  10. Data show that TGFbeta (Montrer TGFB1 Anticorps)-activated kinase-1 (TAK1 (Montrer NR2C2 Anticorps)) activated nuclear factor of activated T-cells (NFAT (Montrer NFATC1 Anticorps))/NF-kappa B (NFkappaB (Montrer NFKB1 Anticorps)), downregulated BCL2-adenovirus E1B interacting protein 3 (Bnip3 (Montrer BNIP3 Anticorps)), and inhibited cardiac cell death.

MAP3K7 profil antigène

Antigen Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with MAP3K7

  • mitogen activated protein kinase kinase kinase 7 (map3k7) anticorps
  • mitogen activated protein kinase kinase kinase 7 (Map3k7) anticorps
  • mitogen-activated protein kinase kinase kinase 7 (MAP3K7) anticorps
  • mitogen-activated protein kinase kinase kinase 7 (Map3k7) anticorps
  • B430101B05 anticorps
  • C87327 anticorps
  • MEKK7 anticorps
  • si:ch211-225h9.1 anticorps
  • TAK1 anticorps
  • TGF1a anticorps
  • zgc:110612 anticorps

Protein level used designations for MAP3K7

mitogen-activated protein kinase kinase kinase 7 , tak1 , TGF-beta-activated kinase TAK1 , TGF-beta activated kinase 1 , TGF-beta-activated kinase 1 , transforming growth factor-beta-activated kinase 1 , mitogen activated protein kinase kinase kinase 7 , transforming growth factor beta-activated kinase 1

GENE ID SPECIES
553788 Danio rerio
313121 Rattus norvegicus
6885 Homo sapiens
26409 Mus musculus
529146 Bos taurus
100171454 Pongo abelii
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