Aperçu des produits pour anti-SQSTM1 (SQSTM1) Anticorps

Full name:
anti-Sequestosome 1 Anticorps (SQSTM1)
Chez www.anticorps-enligne.fr sont 307 Sequestosome 1 (SQSTM1) Anticorps de 22 de différents fournisseurs disponibles. De plus, nous expédions SQSTM1 Protéines (14) et SQSTM1 Kits (8) et beaucoup plus de produits pour cette protéine. Un total de 344 SQSTM1 produits sont actuellement listés.
Synonymes:
A170, MGC79491, OSF-6, Osi, OSIL, p60, p62, p62B, PDB3, sb:cb621, sqstm1, STAP, zgc:85784, ZIP, ZIP3

Réactivités les plus populaires pour anti-SQSTM1 (SQSTM1) Anticorps

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anti-Human SQSTM1 Anticorps:

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anti-SQSTM1 Anticorps mieux référencés

  1. Human Polyclonal SQSTM1 Primary Antibody pour IF, IHC (p) - ABIN388979 : Seibenhener, Babu, Geetha, Wong, Krishna, Wooten: Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation. dans Molecular and cellular biology 2004 (PubMed)
    Show all 22 references for 388979

  2. Human Polyclonal SQSTM1 Primary Antibody pour DB - ABIN1881831 : Visconti, Langston, Alonso, Goodman, Selby, Fraser, Ralston: Mutations of SQSTM1 are associated with severity and clinical outcome in paget disease of bone. dans Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010 (PubMed)
    Show all 5 references for 1881831

  3. Human Polyclonal SQSTM1 Primary Antibody pour WB - ABIN1881829 : Ding, Ni, Li, Liao, Chen, Stolz, Dorn, Yin: Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming. dans The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for 1881829

  4. Human Polyclonal SQSTM1 Primary Antibody pour IF (p), IHC (p) - ABIN682153 : Cui, Luo, Li, Li, Wang: Changes of intracellular Ca2+ in quercetin-induced autophagy progression. dans Acta biochimica et biophysica Sinica 2015 (PubMed)
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  5. Human Monoclonal SQSTM1 Primary Antibody pour IF, ELISA - ABIN393579 : Xia, Liu, Xie, Zhu, Guerra, Shen, Yeddula, Fischer, Low, Zhou, Zhang, Oldfield, Verma: A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin. dans Science translational medicine 2014 (PubMed)

  6. Human Polyclonal SQSTM1 Primary Antibody pour ICC, IF - ABIN449246 : Zhang, Gui, Huang, Deng, Fang, Ke, He, Li, Fang: Neuroprotective Effects of β-Asarone Against 6-Hydroxy Dopamine-Induced Parkinsonism via JNK/Bcl-2/Beclin-1 Pathway. dans Molecular neurobiology 2016 (PubMed)

  7. Human Polyclonal SQSTM1 Primary Antibody pour ICC, IF - ABIN449244 : Eason, Bell, Marshall, Rodgers, Pineda, Steiger, Al-Riyami, Harnett, Harnett: The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ. dans Scientific reports 2016 (PubMed)

  8. Human Monoclonal SQSTM1 Primary Antibody pour ELISA, FACS - ABIN4343162 : Shen, Chen, He, Chen, Song, Xiao, Wan, Dai, Pan, Wang: Inhibition of ERα/ERK/P62 cascades induces "autophagic switch" in the estrogen receptor-positive breast cancer cells exposed to gemcitabine. dans Oncotarget 2016 (PubMed)

Plus d’anticorps contre SQSTM1 partenaires d’interaction

Human Sequestosome 1 (SQSTM1) interaction partners

  1. Authors found that p62/SQSTM1, a protein upregulated in liver parenchymal cells but downregulated in HCC (Montrer FAM126A Anticorps)-associated HSCs, negatively controls hepatic stellate cells activation.

  2. necessary for retinal pigmented epithelial cytoprotection under oxidative stress; NFkappaB p65 activity may be critical upstream initiator of p62 expression in retinal pigmented epithelial cells under oxidative stress

  3. p62/SQSTM1, which accumulates in autophagy-defective cells, directly binds to and inhibits nuclear RNF168 (Montrer RNF168 Anticorps), an E3 ligase essential for histone H2A ubiquitination and DNA damage responses. As a result, DNA repair proteins such as BRCA1, RAP80 (Montrer UIMC1 Anticorps), and Rad51 (Montrer RAD51 Anticorps) cannot be recruited to the sites of DNA double-strand breaks (DSBs), which impairs DSB repair.

  4. propose that the interplay between LRRK2 (Montrer LRRK2 Anticorps) and p62 (Montrer GTF2H1 Anticorps) may contribute to the pathophysiological function and homeostasis of LRRK2 (Montrer LRRK2 Anticorps) protein

  5. Frontotemporal dementia -linked mutations in gene p62/SQSTM1 encoding autophagy adaptor proteins , indicate that impaired autophagy might cause Frontotemporal dementia.

  6. These data suggest that SQSTM1 mutations are not a common cause of normal tension glaucoma.

  7. These results demonstrated that p62-dependent mitophagy has an immunosuppressive role to innate immune response and might serve as a potential immunomodulatory target for inflammation-associated diseases.

  8. siRNA-mediated knockdown of p62 clearly increased the efficiency of transfection of murine embryonic stem (mES) cells and human HeLa cells. These data indicate that p62 acts as a key regulator of gene delivery.

  9. These studies suggest that p62 is involved in the genesis of nuclear factor kappaB-induced proinflammatory and prolabor mediators.

  10. In this review, we discuss p62-mediated signaling pathways and their roles in liver pathophysiology, especially nonalcoholic steatohepatitis and hepatocellular carcinoma

Mouse (Murine) Sequestosome 1 (SQSTM1) interaction partners

  1. Authors found that p62/SQSTM1, a protein upregulated in liver parenchymal cells but downregulated in HCC (Montrer FAM126A Anticorps)-associated HSCs, negatively controls hepatic stellate cells activation.

  2. SQSTM1 or damaged proteins may be transported from the nose to the brain. These findings strongly implicate widespread protein damage in the etiology of flavorings-related lung disease.

  3. Promoting amino acid sensitivity of the mTOR pathway is dependent on p62 accumulation by inhibition of autophagy and this process plays an important role in the hepatic differentiation of stem/progenitor cells.

  4. role of p62 (Montrer GTF2H1 Anticorps) in MDB (Montrer ABR Anticorps) maturation and stability

  5. two ALS-linked factors, SQSTM1 and ALS2 (Montrer ALS2 Anticorps), have distinct but additive protective roles against mutant SOD1 (Montrer SOD1 Anticorps)-mediated toxicity by modulating neuronal proteostasis possibly through the autophagy-endolysosomal system.

  6. These results demonstrated that p62-dependent mitophagy has an immunosuppressive role to innate immune response and might serve as a potential immunomodulatory target for inflammation-associated diseases.

  7. results indicate that autophagy is important for the removal of excess Endoplasmic Reticulum and hepatic CYP enzymes in mouse livers, a process associated with the autophagy receptor protein p62.

  8. p62 (Montrer GTF2H1 Anticorps) reduces UVB-induced apoptosis by modulating intrinsic apoptotic signaling through Src (Montrer SRC Anticorps) phosphorylation.

  9. Our results indicate that JEV replication is impaired in p62-deficient MEFs, suggesting that p62 positively regulates JEV replication in host cells.

  10. Results demonstrate that p62 (Montrer GTF2H1 Anticorps) facilitates activation of NRF2 (Montrer NFE2L2 Anticorps) and mTORC1 and is essential for hepatocellular carcinomas (HCC (Montrer FAM126A Anticorps)) initiation.

Zebrafish Sequestosome 1 (SQSTM1) interaction partners

  1. Loss-of-function of SQSTM1 may cause phenotypic features characterized by locomotor deficits and motor neuron axonal defects that are associated with a misregulation of autophagic processes.

SQSTM1 profil antigène

Antigen Summary

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Alternative names and synonyms associated with SQSTM1

  • sequestosome 1 (SQSTM1) anticorps
  • sequestosome 1 (LOC100342157) anticorps
  • sqstm1 protein (sqstm1) anticorps
  • sequestosome 1 (Sqstm1) anticorps
  • sequestosome 1 (sqstm1) anticorps
  • A170 anticorps
  • MGC79491 anticorps
  • OSF-6 anticorps
  • Osi anticorps
  • OSIL anticorps
  • p60 anticorps
  • p62 anticorps
  • p62B anticorps
  • PDB3 anticorps
  • sb:cb621 anticorps
  • sqstm1 anticorps
  • STAP anticorps
  • zgc:85784 anticorps
  • ZIP anticorps
  • ZIP3 anticorps

Protein level used designations for anti-Sequestosome 1 (SQSTM1) Anticorps

sequestosome 1 , sequestosome-1 , sequestosome-1-like , sqstm1 protein , EBI3-associated protein of 60 kDa , EBI3-associated protein p60 , EBIAP , oxidative stress induced like , phosphotyrosine independent ligand for the Lck SH2 domain p62 , phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa , ubiquitin-binding protein p62 , STONE14 , oxidative stress induced , PKC-zeta-interacting protein , protein kinase C-zeta-interacting protein

GENE ID SPECIES
462333 Pan troglodytes
705481 Macaca mulatta
770805 Gallus gallus
100135450 Ovis aries
100342157 Oryctolagus cuniculus
100385650 Callithrix jacchus
493277 Xenopus (Silurana) tropicalis
100067231 Equus caballus
8878 Homo sapiens
18412 Mus musculus
113894 Rattus norvegicus
406452 Danio rerio
379610 Xenopus laevis
338045 Bos taurus
481459 Canis lupus familiaris
100172461 Pongo abelii
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