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Aperçu des produits pour anti-TRADD (TRADD) Anticorps

Full name:
anti-TNFRSF1A-Associated Via Death Domain Anticorps (TRADD)
Chez www.anticorps-enligne.fr sont 114 TNFRSF1A-Associated Via Death Domain (TRADD) Anticorps de 23 de différents fournisseurs disponibles. De plus, nous expédions TRADD Protéines (14) et TRADD Kits (3) et beaucoup plus de produits pour cette protéine. Un total de 139 TRADD produits sont actuellement listés.
Synonymes:
9130005N23Rik, AA930854, Hs.89862, tradd, wu:fc59e02, zgc:103556
afficher tous les anticorps Gène GeneID UniProt
TRADD 8717 Q15628
TRADD 71609 Q3U0V2
TRADD 246756  

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Réactivités les plus populaires pour anti-TRADD (TRADD) Anticorps

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anti-Human TRADD Anticorps:

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anti-TRADD Anticorps mieux référencés

  1. Human Monoclonal TRADD Primary Antibody pour IF, IP - ABIN968045 : He, Ting: A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells. dans Molecular and cellular biology 2002 (PubMed)
    Show all 5 references for ABIN968045

  2. Human Monoclonal TRADD Primary Antibody pour WB - ABIN967541 : Hsu, Shu, Pan, Goeddel: TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. dans Cell 1996 (PubMed)
    Show all 3 references for ABIN967541

  3. Human Polyclonal TRADD Primary Antibody pour EIA, FACS - ABIN955307 : Pointon, Harvey, Karaderi, Appleton, Farrar, Stone, Sturrock, Reveille, Weisman, Ward, Brown, Wordsworth: The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-associated death domain (TRADD). dans Annals of the rheumatic diseases 2010 (PubMed)
    Show all 2 references for ABIN955307

  4. Human Polyclonal TRADD Primary Antibody pour IHC (p), IHC - ABIN407974 : Chakraborty, Li, Tang, Xie, Puliyappadamba, Raisanen, Burma, Boothman, Cochran, Wu, Habib: Cytoplasmic TRADD confers a worse prognosis in glioblastoma. dans Neoplasia (New York, N.Y.) 2013 (PubMed)

  5. Human Polyclonal TRADD Primary Antibody pour IP, IHC - ABIN223257 : Chen, Texada, Duggan, Liang, Reden, Kooragayala, Langford: Surface calreticulin mediates muramyl dipeptide-induced apoptosis in RK13 cells. dans The Journal of biological chemistry 2005 (PubMed)

  6. Human Polyclonal TRADD Primary Antibody pour IF (p), IHC (p) - ABIN673314 : Chen, Zhang, Zhang, Li, Sun: Hydrogen sulfide protects against TNF-α induced neuronal cell apoptosis through miR-485-5p/TRADD signaling. dans Biochemical and biophysical research communications 2016 (PubMed)

  7. Dog (Canine) Polyclonal TRADD Primary Antibody pour WB - ABIN2792121 : Miyagawa, Yamai, Sakaguchi, Kiyohara, Tsukamoto, Kimoto, Nakamura, Lee, Tsai, Chiang, Shimoda, Harada, Tahira, Hayashi, Horiuchi: Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus. dans Rheumatology (Oxford, England) 2008 (PubMed)

Plus d’anticorps contre TRADD partenaires d’interaction

Human TNFRSF1A-Associated Via Death Domain (TRADD) interaction partners

  1. By reducing the levels of TRADD, wild type CFTR suppresses downstream proinflammatory NFkappaB signaling.

  2. NPM (Montrer NPM1 Anticorps)-RAR (Montrer RARA Anticorps) binding to TRADD selectively inhibits caspase (Montrer CASP3 Anticorps) activation, while allowing activation of NFkappaB (Montrer NFKB1 Anticorps) and JNK (Montrer MAPK8 Anticorps)

  3. The release of extracellular vesicles was triggered by TNFA (Montrer TNF Anticorps) from BEAS-2b cells.TNFA-triggered extracellular vesicles contained TNFR1 (Montrer TNFRSF1A Anticorps) and TRADD.

  4. MicroRNA-30c-2-3p negatively regulates NF-kappaB (Montrer NFKB1 Anticorps) signaling and cell cycle progression through downregulation of TRADD and CCNE1 (Montrer CCNE1 Anticorps) in breast cancer.

  5. domains of calmodulin (Montrer CALM1 Anticorps) mediate FADD (Montrer FADD Anticorps) and TRADD interaction

  6. PA induced the apoptosis of HUVECs by initiating the death pathway (TNF-R1 (Montrer TNFRSF1A Anticorps)/TRADD/caspases 8 pathway), whereas AA enhanced cell survival to protect vascular endothelial cells by activating the survival pathway (TNF-R1 (Montrer TNFRSF1A Anticorps)/RIP (Montrer HRB Anticorps)/NF-kappaB (Montrer NFKB1 Anticorps) 50/NF-kappaB (Montrer NFKB1 Anticorps) 65).

  7. Biologic assessment found that NPM (Montrer NPM1 Anticorps)-RAR (Montrer RARA Anticorps) expression impaired TNF (Montrer TNF Anticorps)-induced signaling through TRADD, blunting TNF (Montrer TNF Anticorps)-mediated activation of caspase-3 (CASP3 (Montrer CASP3 Anticorps)) and caspase-8 (CASP8 (Montrer CASP8 Anticorps)), to ultimately block apoptosis.

  8. TRADD gene expression was knocked down by an antisense oligonucleotide.

  9. structure-based mutations of TNFR-1 (Montrer TNFRSF1A Anticorps) (P367A and P368A), TRADD (F266A), and RIP1 (Montrer UQCRFS1 Anticorps) (M637A and R638A) disrupted formation of the death domain (DD) complex and prevented stable interactions among those DDs

  10. Data indicate that the (Montrer MAP3K5 Anticorps)ASK1-FoxO3a-TRADD-caspase 8 pathway is present in neural tube defects (Montrer FOXO3 Anticorps)(NTDs)-affected tissues.

Mouse (Murine) TNFRSF1A-Associated Via Death Domain (TRADD) interaction partners

  1. Data indicate that ASK1 (Montrer MAP3K5 Anticorps) activation stimulated the activity of the transcription factor FoxO3a (Montrer FOXO3 Anticorps), which increased the abundance of the apoptosis-promoting adaptor protein TRADD, leading to activation of caspase 8 (Montrer CASP8 Anticorps).

  2. data indicate that TRADD shuttles dynamically from the cytoplasm into the nucleus to modulate the interaction between p19(Arf (Montrer CDKN2A Anticorps)) and its E3 ubiquitin ligase (Montrer MUL1 Anticorps) ULF (Montrer TRIP12 Anticorps), thereby promoting p19(Arf (Montrer CDKN2A Anticorps)) protein stability and tumour suppression

  3. Data suggest that deficiency of TRADD sensitizes cells to TRAIL-induced apoptosis, and that enhanced cell death in TRADD(-/-) MEFs is associated with defective NF-kappaB (Montrer NFKB1 Anticorps) activation.

  4. TRADD is required for recruitment of receptor interacting protein 1 (Montrer RIPK1 Anticorps) and TNFR (Montrer TNFRSF1A Anticorps)-associated factor 2 to the DR3 (Montrer TNFRSF25 Anticorps) signaling complex and for the ubiquitination of receptor interacting protein 1 (Montrer RIPK1 Anticorps)

  5. We show that TRADD is recruited to the TRAIL-receptor complex, and RIP1 (Montrer RALBP1 Anticorps) recruitment is mediated by TRADD.

  6. TRADD may be involved in IFN-gamma (Montrer IFNG Anticorps) signaling by forming a complex with STAT1 (Montrer STAT1 Anticorps)-alpha within the nucleus and regulating IFN-gamma (Montrer IFNG Anticorps)-mediated STAT1 (Montrer STAT1 Anticorps)-alpha activation.

  7. Tradd activates distinct mechanisms of apoptosis from the nucleus and the cytoplasm.

  8. silencing TRADD expression with small-interfering RNA reduced neuronal apoptosis and subsequent microglial and astroglial activation

  9. TRADD is a multifunctional protein crucial both for TNFR1 (Montrer TNFRSF1A Anticorps) signaling and other signaling pathways relevant to immune responses.

Cow (Bovine) TNFRSF1A-Associated Via Death Domain (TRADD) interaction partners

  1. TNF (Montrer TNF Anticorps) binding induces release of AIP1 (DAB2IP (Montrer DAB2IP Anticorps)) from TNFR1 (Montrer TNFRSF1A Anticorps), resulting in cytoplasmic translocation and concomitant formation of an intracellular signaling complex comprised of TRADD, RIP1 (Montrer RALBP1 Anticorps), TRAF2 (Montrer TRAF2 Anticorps), and AIPl.

TRADD profil antigène

Antigen Summary

The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.

Alternative names and synonyms associated with TRADD

  • TNFRSF1A-associated via death domain (TRADD) anticorps
  • TNFRSF1A-associated via death domain (LOC100337888) anticorps
  • conjugal transfer protein D (traDd) anticorps
  • TNFRSF1A-associated via death domain (Tradd) anticorps
  • TNFRSF1A-associated via death domain (tradd) anticorps
  • tnfrsf1a-associated via death domain (tradd) anticorps
  • tnfrsf1a-associated via death domain protein (LOC100136668) anticorps
  • 9130005N23Rik anticorps
  • AA930854 anticorps
  • Hs.89862 anticorps
  • tradd anticorps
  • wu:fc59e02 anticorps
  • zgc:103556 anticorps

Protein level used designations for TRADD

TNFRSF1A-associated via death domain , conjugal transfer protein D , TNFR1-associated death domain protein , tumor necrosis factor receptor type 1 associated death domain protein , tumor necrosis factor receptor type 1-associated DEATH domain protein , tumor necrosis factor receptor-1-associated protein , TNF receptor 1 associated signal transducer , TNFR1-associated DEATH domain protein , Tumor necrosis factor receptor type 1-associated DEATH domain protein , TNFRSF1A-associated via death domain protein

GENE ID SPECIES
415700 Gallus gallus
454154 Pan troglodytes
100337888 Oryctolagus cuniculus
7369642 Agrobacterium radiobacter K84
8717 Homo sapiens
71609 Mus musculus
246756 Rattus norvegicus
611262 Canis lupus familiaris
504707 Bos taurus
733418 Xenopus laevis
58130 Danio rerio
100136668 Oncorhynchus mykiss
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