Aperçu des produits pour anti-TRAF6 (TRAF6) Anticorps

Full name:
anti-TNF Receptor-Associated Factor 6 Anticorps (TRAF6)
Chez www.anticorps-enligne.fr sont 156 TNF Receptor-Associated Factor 6 (TRAF6) Anticorps de 31 de différents fournisseurs disponibles. De plus, nous expédions TRAF6 Kits (17) et TRAF6 Protéines (14) et beaucoup plus de produits pour cette protéine. Un total de 207 TRAF6 produits sont actuellement listés.
Synonymes:
2310003F17Rik, AI851288, C630032O20Rik, CG10961, Dmel\\CG10961, dtraf2, dTRAF6, fi15f02, GB10539, MGC:3310, RNF85, TRAF, Traf2, TRAF6, wu:fi15f02, xtraf6, zgc:63704

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anti-TRAF6 Anticorps mieux référencés

  1. Human Polyclonal TRAF6 Primary Antibody pour WB - ABIN1881900 : Hinz, Stilmann, Arslan, Khanna, Dittmar, Scheidereit: A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation. dans Molecular cell 2010 (PubMed)
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  2. Cow (Bovine) Polyclonal TRAF6 Primary Antibody pour WB - ABIN2779305 : Jazdzewski, Murray, Franssila, Jarzab, Schoenberg, de la Chapelle: Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma. dans Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

  3. Human Polyclonal TRAF6 Primary Antibody pour IF (p) - ABIN918441 : Qi, Pradipta, Li, Zhao, Lu, Fu, Wei, Hsung, Tanaka, Zhou: Cinchonine induces apoptosis of HeLa and A549 cells through targeting TRAF6. dans Journal of experimental & clinical cancer research : CR 2017 (PubMed)

Plus d’anticorps contre TRAF6 partenaires d’interaction

Fruit Fly (Drosophila melanogaster) TNF Receptor-Associated Factor 6 (TRAF6) interaction partners

  1. we found that reactive oxygen species-induced autophagy acts as a negative feedback regulator of JNK (Montrer MAPK8 Anticorps) activity by dissociating Atg9 (Montrer ATG9A Anticorps)/mAtg9 (Montrer ATG9A Anticorps) from dTRAF2/TRAF6 in Drosophila.

  2. null mutant of DTRAF2 showed immune deficiencies in which NF-kappaB nuclear translocation and antimicrobial gene transcription against microbial infection were severely impaired

Mouse (Murine) TNF Receptor-Associated Factor 6 (TRAF6) interaction partners

  1. TRAF6 mediates lysine-63 ubiquitination within the SH2 (Montrer MYO15 Anticorps) domain of STAT3 (Montrer STAT3 Anticorps), which is an essential step for STAT3 (Montrer STAT3 Anticorps) membrane recruitment and phosphorylation in response to S Typhimurium infection; results reveal a strategy in which S Typhimurium T3SS effectors broaden their functions through the activation of host proteins in a ubiquitination-dependent manner to manipulate host cells into becoming a Salmonella-friendly zone

  2. this study shows that an interaction of TRAF6 with cullin-5 (Montrer CUL5 Anticorps) promotes TRAF6 polyubiquitination and lipopolysaccharide signaling

  3. Consistent with cellular studies, icaritin downregulated TRAF6 and NFATc1 protein expression in CD11b(+) /Gr-1(-/low) osteoclast precursors

  4. Data (including data from studies using knockout mice) suggest that RANKL (Montrer TNFSF11 Anticorps) enhances TNF (Montrer TNF Anticorps)-induced osteoclast formation from precursor spleen cells and enhances bone resorption independently of Traf6 by degrading Traf3 (Montrer TRAF3 Anticorps), a known inhibitor of osteoclastogenesis. (RANKL (Montrer TNFSF11 Anticorps) = osteoclast differentiation factor (Montrer TNFSF11 Anticorps); TNF (Montrer TNF Anticorps) = tumor necrosis factor (Montrer TNF Anticorps); Traf (Montrer TRAF1 Anticorps) = TNF (Montrer TNF Anticorps) receptor-associated factor)

  5. the SH3 domain (Montrer ITSN1 Anticorps) of NOSTRIN (Montrer NOSTRIN Anticorps) is involved in the NOSTRIN (Montrer NOSTRIN Anticorps)-TRAF6 interaction and is required for NOSTRIN (Montrer NOSTRIN Anticorps)-induced down-regulation of endothelial cell proteins

  6. this study shows that TRAF6 overexpression in hematopoietic stem/progenitor cells results in impaired hematopoiesis and bone marrow failure

  7. TRAF6 and H2AX (Montrer H2AFX Anticorps) overexpression and gammaH2AX (Montrer H2AFX Anticorps)-mediated HIF1alpha (Montrer HIF1A Anticorps) enrichment in the nucleus of cancer cells lead to overactivation of HIF1alpha (Montrer HIF1A Anticorps)-driven tumorigenesis, glycolysis and metastasis.

  8. By studying the response of T (Montrer IFT122 Anticorps)raf6(+/+) and Traf6(-/-)mouse embryonic fibroblasts to S. typhimurium infection, this study showed that TRAF6 promoted apoptosis by increasing reactive oxygen species accumulation, which led to increased Bax/Bcl-2 ratio, Bax recruitment to mitochondrial membrane, and release of Cyt c into the cytoplasm.

  9. BAT3 (Montrer BAT3 Anticorps) negatively regulates lipopolysaccharide-induced NF-kappaB (Montrer NFKB1 Anticorps) signaling through TRAF6.

  10. these data identify Trim13 (Montrer TRIM13 Anticorps) as a positive regulator of NF-kappaB (Montrer NFKB1 Anticorps) activation and suggest that lysine 29-linked polyubiquitination is a specific ubiquitin-linked pattern involved in the control of TLR2 (Montrer TLR2 Anticorps) signaling.

Zebrafish TNF Receptor-Associated Factor 6 (TRAF6) interaction partners

  1. we have now analyzed the in vivo function of Traf6 in the innate immune response without interference of adaptive immunity

  2. Full-length traf6 was functionally characterized.

Human TNF Receptor-Associated Factor 6 (TRAF6) interaction partners

  1. The E3 ligase TRAF6 binds to DCP1a (Montrer DCP1A Anticorps) and indirectly regulates DCP1a (Montrer DCP1A Anticorps) phosphorylation, expression of decapping factors, and gene-specific mRNA decay.

  2. Study showed that patients without a history of atrial fibrillation who develop postoperative atrial fibrillation have a higher percentage of left atrial fibrosis, increased expression of TRAF6, higher serum Ang II (Montrer AGT Anticorps) levels, and changes in the activities of the MAPKs/TGF-beta1 (Montrer TGFB1 Anticorps)/TRAF6 pathway.

  3. Low TRAF6 expression is associated with graft-versus-host disease.

  4. Consistent with cellular studies, icaritin downregulated TRAF6 and NFATc1 protein expression in CD11b(+) /Gr-1(-/low) osteoclast precursors

  5. Results suggest that overexpression of miR (Montrer MLXIP Anticorps)-146a could promote IDD (Montrer COL9A3 Anticorps) through the TRAF (Montrer TRAF1 Anticorps)/NF-kappaB (Montrer NFKB1 Anticorps) pathway.

  6. TRAF6 and H2AX (Montrer H2AFX Anticorps) overexpression and gammaH2AX (Montrer H2AFX Anticorps)-mediated HIF1alpha (Montrer HIF1A Anticorps) enrichment in the nucleus of cancer cells lead to overactivation of HIF1alpha (Montrer HIF1A Anticorps)-driven tumorigenesis, glycolysis and metastasis.

  7. These findings show that SopB (Montrer IFT122 Anticorps) suppresses host cell apoptosis by binding to TRAF6 and preventing mitochondrial reactive oxygen species generation.

  8. HCV infection suppressed the host innate immune response through the induction of autophagic degradation of TRAF6. This finding provided important information for further understanding how HCV evades host immunity to establish persistence

  9. Vav3 (Montrer VAV3 Anticorps) is a novel TRAF6 interaction partner that functions in the activation of cooperative signaling between T6BSs and the IVVY motif in the RANK signaling complex.

  10. TRAF6 expression was decreased in tympanic membrane of otitis media patients.

TRAF6 profil antigène

Antigen Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.

Alternative names and synonyms associated with TRAF6

  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (traf6-b) anticorps
  • TNF-receptor-associated factor 6 (Traf6) anticorps
  • TNF receptor-associated factor 6 (TRAF6) anticorps
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (traf6) anticorps
  • TNF receptor-associated factor 6 (traf6) anticorps
  • TNF receptor-associated factor 6 (Traf6) anticorps
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6) anticorps
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (Traf6) anticorps
  • 2310003F17Rik anticorps
  • AI851288 anticorps
  • C630032O20Rik anticorps
  • CG10961 anticorps
  • Dmel\\CG10961 anticorps
  • dtraf2 anticorps
  • dTRAF6 anticorps
  • fi15f02 anticorps
  • GB10539 anticorps
  • MGC:3310 anticorps
  • RNF85 anticorps
  • TRAF anticorps
  • Traf2 anticorps
  • TRAF6 anticorps
  • wu:fi15f02 anticorps
  • xtraf6 anticorps
  • zgc:63704 anticorps

Protein level used designations for TRAF6

TNF receptor-associated factor 6-B , E3 ubiquitin-protein ligase TRAF6 , CG10961-PA , TNF-receptor-associated factor 2 , Traf6-PA , TNF receptor-associated factor 6 , TNF receptor-associated factor 6-like , RING finger protein 85 , interleukin-1 signal transducer , TNF-receptor associated factor 6

GENE ID SPECIES
444777 Xenopus laevis
31746 Drosophila melanogaster
423163 Gallus gallus
451702 Pan troglodytes
493524 Xenopus (Silurana) tropicalis
551819 Apis mellifera
100010055 Monodelphis domestica
100174890 Gasterosteus aculeatus
100395364 Callithrix jacchus
100449432 Pongo abelii
100510771 Anolis carolinensis
100544809 Meleagris gallopavo
100595327 Nomascus leucogenys
22034 Mus musculus
539124 Bos taurus
554561 Danio rerio
7189 Homo sapiens
311245 Rattus norvegicus
100688110 Canis lupus familiaris
396629 Sus scrofa
716907 Macaca mulatta
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